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MRP: Rs. 85.71 for 1 strip(s) (10 tablets each)
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Composition for SAFELINE M

Gliclazide(80 mg),Metformin(500 mg)

food interaction for SAFELINE M

alcohol interaction for SAFELINE M

pregnancy interaction for SAFELINE M

lactation interaction for SAFELINE M

There is no data available. Please consult doctor before consuming the drug.
Taking metformin with alcohol may cause lactic acidosis and you may experience malaise, respiratory distress, slow or irregular heartbeat, somnolence, abdominal upset, or other unusual symptoms.
Human and animal studies are not available. Please consult your doctor.
Safeline m 80mg/500mg tablet is probably unsafe to use during breastfeeding. Please consult your doctor.


Gliclazide(80 mg)


Gliclazide is used to lower the blood sugar levels in type 2 diabetes mellitus when diet, physical exercise and weight reduction alone are not adequate. 

How it works

Gliclazide belongs to a blood sugar lowering group of medicines called sulfonylurea. Gliclazide increases the amount of insulin released by the pancreas, and thereby decreases the blood sugar level.

Common side effects

Nausea, Abdominal pain, Abnormal blood cell, Angioedema (swelling of deeper layers of skin), Blisters on skin, Skin peeling, Constipation, Decreased blood cell count, Diarrhoea, Decreased sugar level in blood, Indigestion, Rash, Visual impairment, Vomiting
Metformin(500 mg)


Metformin is an antidiabetic medicine that helps to control blood sugar in people with type 2 diabetes mellitus.

How it works

Metformin belongs to class of medications called antidiabetics.It decreases the amount of glucose absorbed from the food and the amount ofglucose made by liver. Metformin also increases the body's response to insulin(a natural substance that controls the amount of glucose in the blood).

Common side effects

Flatulence, Muscle pain, Abdominal bloating, Chest pain, Skin rash, Flushing, Abdominal pain, Nail disorder, Diarrhoea, Headache, Indigestion, Bitter taste, Constipation, Allergic reaction, Heartburn


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Expert advice for SAFELINE M

  • Do not chew the tablet, and swallow the whole tablet with a glass of water or non-alcoholic drink just before a meal.
  • Do not take gliclazide, if you have type 1 diabetes mellitus or have impaired consciousness due to severe diabetes, liver or kidney disease, or deficiency of an enzyme called glucose-6-phosphate dehydrogenase.
  • Do not take gliclazide if you are pregnant or breast-feeding.

Frequently asked questions for SAFELINE M


Q. Is gliclazide same or, better than metformin?
Gliclazide and metformin belong to different class of drugs and act but separate mechanism. No significant difference between gliclazide and metformin was reported in clinical studies as regards their ability to reduce blood sugar.
Q. Is gliclazide the same as glipizide?
No,gliclazide and glipizide belong to a class of drugs known as sulphonylureas.
Q. Is gliclazide a statin or, steroid?
No,gliclazide belongs to sulfonylurea category of antidiabetic drug class.
Q. What is Glizid M?
Glizid M is a combination product that contains gliclazide and metformin. Both drugs are used to lower blood glucose levels in adult with type 2 diabetes mellitus that is not controlled by diet and exercise alone.


Q. Is Metformin a birth control pill/ insulin / statin/ banned drug?
Metformin (also available as glyciphage, glycomet, glycomet SR) is an antidiabetic drug used in treatment of type 2 diabetes mellitus, particularly in overweight patients, as an adjunct to the diet and exercise.
Q. Is metformin safe?
Metformin is generally safe if used at prescribed doses for the prescribed duration as advised by your doctor.
Q. Can I take metformin forever?
Metformin should be taken at prescribed doses for the prescribed duration as advised by your doctor.
Q. Is metformin good for weight loss / weight loss in non-diabetics?
Metformin is used for the treatment of type 2 diabetes mellitus, particularly in overweight patients. 


Content on this page was last updated on 07 March, 2016, by Dr. Varun Gupta (MD Pharmacology)