Rozat 20mg Tablet

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Dr Reddy's Laboratories Ltd

Composition for Rozat 20mg Tablet

iconPrescription Required
Potentiallyunsafewith
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Alcohol
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Pregnancy
215.2
₹15.37/Tablet
14 tablets in 1 strip
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Medicine Overview of Rozat Tablet

uses

Uses of Rozat Tablet

Rozat 20mg Tablet is used in the treatment of increased cholesterol and increased triglycerides.
uses

Side effects of Rozat Tablet

Common

Headache, Stomach pain, Constipation, Feeling sick, Muscle pain, Weakness, Dizziness, Increased glucose level in blood.

uses

How to use Rozat Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Rozat 20mg Tablet may be taken with or without food, but it is better to take it at a fixed time.

How Rozat Tablet works

Rozat 20mg tablet is a lipid-lowering medication (statins). It works by blocking an enzyme (HMG-CoA-reductase) that is required in the body to make cholesterol. It thus lower "bad" cholesterol (LDL), triglycerides and raise "good" cholesterol (HDL).

In Depth Information on Rozat Tablet

Expert advice for Rozat Tablet

  • Rozat lowers "bad" cholesterol (LDL). It helps prevent heart attack and stroke.
  • Regular exercise and low-fat diet further help to lower levels of fat in the blood.
  • Rozat prevents one death in every 50 patients with heart disease treated over 4 to 5 years.
  • It is better to take in the evening.
  • In general, Rozat is safe. It may cause digestive problems like diarrhoea, gas. If any of these happen to you, take it with food.
  • Notify your doctor if you are more tired than usual, do not feel hungry, or if you have yellow eyes, skin or dark urine.
  • Notify your doctor if you experience muscle symptoms (pain or weakness), particularly if you have fever, a sick feeling or dark urine.
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Warnings
Special precautions for Rozat 20mg Tablet
Alcohol
CAUTION
Taking alcohol with Rosuvastatin increases the chances of liver dysfunction.
Pregnancy
CAUTION
Rozat 20mg Tablet is highly unsafe to use during pregnancy.

Human and animal studies have shown significant adverse effects on the foetus. Please consult your doctor.
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Lactation
CAUTION
Rozat 20mg Tablet is probably usafe to use during lactation.
Limited human data suggests that the drug could represent a significant risk to the baby.
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Driving
SAFE
Rozat 20mg Tablet does not usually affect your ability to drive.
Kidney
CAUTION
Rozat 20mg Tablet should be used with caution in patients with kidney disease. Dose adjustment of Rozat 20mg Tablet may be needed. Please consult your doctor.

Use of Rozat 20mg Tablet is not recommended in patients with severe kidney disease.
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Liver
CAUTION
Rozat 20mg Tablet should be used with caution in patients with liver disease. Dose adjustment of Rozat 20mg Tablet may be needed. Please consult your doctor.

Use of Rozat 20mg Tablet is not recommended in patients with severe liver disease and active liver disease.
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Severely interacts with other drugs like
Itragreat 200mg Capsule, Itragreat 100mg Capsule, Flutis 150mg Tablet, Azibey 200mg Suspension

Missed Dosageuses

If you miss a dose of Rosuvastatin, skip it and continue with your normal schedule. Do not double the dose.
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Patient Concerns

Frequently asked questions for Rozat 20mg Tablet

Frequently asked questions for Rosuvastatin

Cholesterol is a type of fat present in your blood. Your total cholesterol is made up of LDL and HDL cholesterol. LDL cholesterol is called “bad” cholesterol as it can build up in the wall of your blood vessels and slow or obstruct blood flow to your heart, brain, and other organs. This can cause heart diseases and stroke. HDL cholesterol is called “good” cholesterol as it prevents the bad cholesterol from building up in the blood vessels. Triglycerides also are harmful fats found in your blood.
Clinical studies have shown that Rozatw is well tolerated in patients even after long-term use and is relatively safe. However, it has its own side effects and hence should only be used in the dose, and for the duration as advised by your doctor.
No, Rozat is not a blood thinner. It is a lipid-lowering medicine and belongs to a group of medicines known as HMG-CoA reductase inhibitors.
Q. Is Rozat better than atorvastatin?
In clinical studies, Rozat, when compared to an equal dose of atorvastatin, had a better lipid lowering effect. There was no significant difference in the safety profile of both the drugs.
Q. Is Rozat same as simvastatin?
Rozat and simvastatin are different drugs. However, they belong to the same group of drugs called HMG-CoA reductase inhibitor and both are used for lowering high lipid levels in the blood.
Q. Can I take Rozat with ibuprofen?
Rozat can be safely taken with ibuprofen. There are no reported drug-drug interactions or harmful effects when they are used together.
Q. Can I take Rozat with magnesium?
Magnesium taken as a health supplement is not known to have any interaction with Rozat. However, taking the drug with antacids containing magnesium hydroxide can decrease the amount of Rozat in the body by half and the effectiveness of Rozat may decrease. So, antacids should be taken at least two hours after taking Rozat.
Q. Can I take Rozat with ranitidine?
Rozat can be taken with ranitidine. There are no reported drug-drug interactions or harmful effects when they are used together.
Q. Can you take Rozat with levothyroxine?
Levothyroxine is not known to have any interaction with Rozat. Consult your doctor before taking the two medicines together as the high cholesterol could be due to hypothyroidism for which you are given levothyroxine. Rozat should be used with caution in patients having high cholesterol due to hypothyroidism especially if the underlying disease is not properly treated.
Rozat is not known to have any effect on weight. Weight loss with this drug has only been reported by some patient and is seen in some animal studies. But there are no human research studies to show weight loss with Rozat. However, if you notice any change in body weight during therapy, consult your doctor as it could be due to some underlying condition that needs attention.
Rozat use is seen to be associated with an increase in blood sugar levels in clinical studies. The increase is similar to as seen in a diabetic patient and you may need treatment for the same. Consult your doctor before taking Rozat if you are a diabetic.
Rozat use is not associated with erectile dysfunction. If you have this problem, this could be due to some other underlying condition and you may need to consult a doctor.
Yes, Rozat can lower triglyceride levels. It also lowers total cholesterol and LDL cholesterol levels and increase the HDL levels.
Rozat is not known to cause weight gain. However, if you notice any change in body weight during therapy, consult your doctor as there could be some other underlying condition that needs attention like fluid overload (water retention) in the body due to some heart, kidney or liver disease.
Rozat is not known to cause dry mouth. Common side effects seen with its use are musculoskeletal (bone, muscle or joint) pain, allergic reaction, headache, nausea, dyspepsia, nasopharyngitis, increased liver enzymes, increased creatine phosphokinase (CPK) level in blood, diarrhea, flatulence, constipation, joint swelling and increased glucose level in blood
Rozat is not known to increase blood pressure. Common side effects seen with its use are musculoskeletal (bone, muscle or joint) pain, allergic reaction, headache, nausea, dyspepsia, nasopharyngitis, increased liver enzymes, increased creatine phosphokinase (CPK) level in blood, diarrhea, flatulence, constipation, joint swelling and increased glucose level in blood.
Rozat use is not associated with hair loss. Common side effects seen with its use are muscle damage, musculoskeletal (bone, muscle or joint) pain, allergic reaction, headache, nausea, dyspepsia, nasopharyngitis, increased liver enzymes, increased creatine phosphokinase (CPK) level in blood, diarrhea, flatulence, constipation, joint swelling and increased glucose level in blood.
Muscle pain is one of the common side effects associated with Rozat use. Be careful and look for any muscle symptoms like muscle pain, tenderness, or weakness or dark colored urine. If you have any of these symptoms, stop taking Rozat and immediately inform your doctor. These symptoms could be due to muscle breakdown and release of muscle proteins into the blood stream (this condition is known as rhabdomyolysis) and this can lead to problems like kidney failure.
Yes, Rozat can be taken with grapefruit juice. No drug-drug interactions or any harmful effects have been reported when they are used together.
Q. Can I take Rozat with clopidogrel?
Rozat can be taken along with clopidogrel. Rozat does not interfere with the antiplatelet action of clopidogrel.However, a high dose of clopidogrel can increase the Rozat blood concentration by 2-fold causing more chances of the side effects, so a dose adjustment for Rozat may be needed.
Q. Which is more beneficial in the management of cardiovascular diseases - Rozat or atorvastatin?
Both Rozat and Atorvastatin are seen to be equally safe and effective in lowering bad cholesterol, increasing good cholesterol and possibly reversing plaque formation when given in their maximum doses. However, Rozat is seen to decrease LDL cholesterol better than Atorvastatin in many studies but the difference was not significant in terms of slowing disease progression and improving clinical outcomes.
Yes, Rozat can be taken along with vitamin D. No drug-drug interactions or any harmful effects have been reported when they are used together.
Q. Can the use of Rozat increase vitamin D levels in your body?
Rozat has shown to increase vitamin D levels in many clinical research studies. In some studies, the rise has been up to three times the base level. However, the mechanism by which it increases the vitamin D levels is still not clear.
Rozat acts by blocking an enzyme which is important for cholesterol synthesis in our body. The activity of this enzyme is more at night time, so, it is advisable to take Rozat in the evening hours after a meal or just before going to bed to have maximum effect. However, Rozat being a longer acting statin can be taken at any time of day.
Q. Would a combination of ezetimibe and simvastatin be better than Rozat alone?
Ezetimibe and Simvastatin are used to treat high cholesterol and triglyceride levels along with a proper diet. Together they are useful in preventing conditions like heart attack and stroke by delaying the formation of plaques in the blood vessels. In one of the clinical studies, ezetimibe and simvastatin combination was found to be better than Rozat alone in decreasing the LDL-cholesterol, other non-HDL-cholesterol, and total cholesterol especially in high-risk patients (uncontrolled hyperlipidemia or obese patients).
Q. How is Rozat different from lovastatin?
Both Rozat and lovastatin belong to the same class of drugs and are used to manage high blood cholesterol levels. However, Rozat is more effective in lowering blood cholesterol and its action stays for a long time and it can be taken at any time of the day whereas lovastatin is to be taken only in the evening. The dose of lovastatin needs adjustment in patients with the moderate-to-severe renal disease while a dose of lovastatin needs adjustment only in severe renal disease.
Q. How is Rozat better than pravastatin?
Both Rozat and pravastatin belong to the same class of drugs and are used to manage high blood cholesterol levels. However, Rozat is more effective in lowering blood cholesterol and its action stays for a long time and it can be taken at any time of the day whereas pravastatin is to be taken only in the evening. Also, Rozat can be taken with or without food while food interferes with the absorption of pravastatin.
Q. Can I take Rozat with quetiapine?
Yes, Rozat can be used along with quetiapine. No drug-drug interactions or any harmful effects have been reported when they are used together.
Q. Can I take Rozat with coenzyme q10?
Rozat can be taken with coenzyme Q10. According to some clinical studies, coenzyme Q10 can help in decreasing the muscle damage caused by Rozat while some of the studies say that it has no role in preventing muscle damage. Also, Rozat has been thought to decrease the levels of coenzyme Q10. So, it is advised sometimes to use coenzyme Q10 along with Rozat to decrease its side effects.
Q. Can I take Rozat with diphenhydramine?
Yes, Rozat can be used along with diphenhydramine. No drug-drug interactions or any harmful effects have been reported when they are used together.
Q. Can I take Rozat with pantoprazole?
Yes, Rozat can be used along with pantoprazole. No drug-drug interactions or any harmful effects have been reported when they are used together.
Q. Is it safe to take Rozat with gemfibrozil?
Concomitant use of Rozat with gemfibrozil should be avoided. Gemfibrozil can increase the blood levels of Rozat and damage your muscles. If you are taking both the drugs, be careful and look for any muscle symptoms. Inform your doctor if you have muscle pain, tenderness, or weakness or dark colored urine.
Q. What is the benefit of taking Rozat with ezetimibe?
Rozat, when used with ezetimibe, helps in a better decrease in LDLcholesterol and triglyceride levels compared to Rozat alone and without any increase in side effects. This combination is very beneficial in high-risk cardiovascular disease patients as its use can decrease the risk of atherosclerotic plaque rupture and heart attack. However, ezetimibe can increase the blood levels of Rozat, so a dose adjustment may be needed when they are used together.
Rozat is not approved for use in the treatment of cancer. Some research studies have shown that Rozat can stop the growth of cancer cells and when given after surgery, it can kill the remaining cancer cells if any and can help in preventing cancer from coming back. Clinical research studies are going on for its use in patients of colon cancer as it may prevent the formation of polyps and the recurrence of colon cancer but this use is still under research and not approved.
Rozat is not indicated for the treatment of weight loss (obesity). Weight loss with this drug has only been reported by some patient and is seen in some animal studies. But there are no human research studies to show weight loss with Rozat.
Yes, Rozat is very useful in the treatment of dyslipidemia, a lipid disorder with very high or very low lipid levels in the blood. Most common lipid disorder is hyperlipidemia in which the patient has high levels of bad lipids (low-density lipoprotein, or LDL) and triglycerides, and low levels of good lipids (high-density lipoprotein, or HDL) in the blood. Rozat along with exercise and a low-fat diet decreases the LDL levels and increases the HDL levels and decrease the risk of heart disease and stroke on long-term use.
Rozat is seen to be useful in preventing new episodes of ischemic stroke in the brain. Ischemic stroke occurs when there is a blockage of the blood vessel of the brain decreasing blood flow to a particular area of the brain. This blockage occurs due to plaque formation (deposition in the arteries where cholesterol combines with fat, calcium, and fibrin). Rozat decreases the chances of plaque formation by lowering the cholesterol levels in the body and hence low-fat the risk of new episodes of stroke. It is not routinely prescribed for the prevention of hemorrhagic stroke.
Rozat is found to be useful in preventing new episodes of ischemic stroke in the brain. Ischemic stroke occurs when there is a blockage of the blood vessel of the brain decreasing blood flow to a particular area of the brain. This blockage occurs due to plaque formation (deposition in the arteries where cholesterol combines with fat, calcium, and fibrin). Rozat decreases the chances of plaque formation by lowering the cholesterol levels in the body and hence lowers the risk of new episodes of stroke. It is not routinely prescribed for the prevention of hemorrhagic stroke.
Q. Can I take Rozat with Febuxostat?
Rozat can be taken with febuxostat. Rozat is used to lower bad cholesterol and Febuxostat is used to lower uric acid levels in patients with gout. Many patients of high cholesterol levels also have high uric acid levels. There are no human studies available on this interaction. However, animal research shows that when given together, febuxostat can increase the blood levels of Rozat causing a higher risk of its side effects like muscle pain and muscle damage. So, a dose adjustment of Rozat may be needed when given along with febuxostat.
Rozat is not used in the treatment of sepsis associated Acute respiratory distress syndrome (ARDS). ARDS is a condition in which there is inflammation of the lung leading to severe organ failure and this could be due to an underlying infection (sepsis). It is seen in some human research studies that there is no useful effect of Rozat in treatment of the sepsis associated ARDS. Rather, it may cause damage to liver and kidney in these patients.
Q. Is there any benefit of taking vitamin C with Rozat?
Rozat can be safely taken with vitamin C. There are no drug-drug interactions reported between the two and no harmful effects have been seen. Rozat is a cholesterol lowering agent used to treat hyperlipidemia. Vitamin C also acts as an anti-oxidant and few studies have shown that vitamin C can also help to lower bad cholesterol. So, using them together can actually be beneficial to lower the blood cholesterol levels.
Q. Can I take calcium supplements with Rozat?
Rozat should not be taken with calcium supplements as calcium can decrease its absorption and hence lowers the blood levels of Rozat. This can lead to a decrease in efficacy of Rozat to lower blood cholesterol levels. To avoid this effect, there should be a gap of at least 2 hours between the two medicines.
No, Rozat is not a narcotic substance. It's a prescription medicine and is available on providing a valid prescription by a doctor.
No, Rozat is not a nitrate. It is a lipid-lowering medicine and belongs to a group of medicines known as HMG-CoA reductase inhibitors.
No, Rozat is not a diuretic. It is a lipid-lowering medicine and is used to lower increased levels of cholesterol and triglycerides in the blood. A diuretic is a medicine, which removes excess water and electrolytes from the body through urine.
No, Rozat is not a beta blocker. It is a lipid-lowering medicine and is used to lower increased levels of cholesterol and triglycerides in the blood.
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“The following are the results of on-going survey on 1mg.com for Rozat 20mg Tablet. These results only indicate the perceptions of the website users. Please base your medical decisions only on the advice of a doctor or a registered medical professional.”
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