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Risperidone(3 mg),Trihexyphenidyl(2 mg)

food interaction for RISCALM PLUS

alcohol interaction for RISCALM PLUS

pregnancy interaction for RISCALM PLUS

lactation interaction for RISCALM PLUS

There is no data available. Please consult doctor before consuming the drug.
Riscalm plus 3mg/2mg tablet may cause excessive drowsiness and calmness with alcohol.
Riscalm plus 3mg/2mg tablet may be unsafe to use during pregnancy.
Animal studies have shown adverse effects on the foetus, however, there are limited human studies. The benefits from use in pregnant women may be acceptable despite the risk. Please consult your doctor.
Riscalm plus 3mg/2mg tablet is probably unsafe to use during breastfeeding. Please consult your doctor.


Risperidone(3 mg)


Risperidone is used in the treatment of schizophrenia (mental disorder in which patient interpret reality abnormally) and mania (abnormally elevated mood)

How it works

Risperidone work by modulating the action of certain chemical messengers in the brain that affects thoughts and mood.

Common side effects

Rash, Joint pain, Headache, Dizziness, Fainting, Blurred vision, Increased appetite, Increased heart rate, Breast enlargement, Vision disorder, Muscle pain, Altered menstrual cycle, Insomnia, Sleepiness, Vomiting, Weakness, Orthostatic hypotension (sudden lowering of blood pressure on standing), Eczema, Dry mouth, Nausea, Abdominal pain, Extra pyramidal symptom, Agitation, Loss of appetite, Upper respiratory tract infection, Dyspepsia, Decreased white blood cell count, Parkinsonism, Weight gain, Fatigue, Anxiety, Akathisia, Fever, Swelling, Increased liver enzymes, Stomach pain, Dry skin, Diarrhoea, Heartburn, Increased blood pressure, Rhinitis, Cough, Dystonia, Altered taste, Drowsiness, Decreased sexual function, Urinary retention, Increased saliva production, Frequent dreams, Respiratory tract infection, Difficulty in urination, Ecg changes, Constipation, Urinary incontinence, Restlessness, Abnormal vision, Skin reaction, Tremor, Seizure
Trihexyphenidyl(2 mg)


Trihexyphenidyl is used in the treatment of parkinson's disease (a disorder of the nervous system that causes difficulties with movement and balance) and drug induced abnormal movements

How it works

Trihexyphenidyl is an anticholinergic agent, which works by blocking the action of a chemical called acetylcholine on the nerves which results in relaxing of smooth muscles; thereby, reducing the rigidity of muscle spasm (sudden involuntary contraction of a muscle or group of muscles), tremor (uncontrolled shaking) and excessive salivation associated with Parkinson’s disease.

Common side effects

Dry mouth, Dry skin, Increased heart rate, Arrhythmia, Excessive thirst, Reduced bronchial secretions, Palpitations, Photophobia, Loss of accommodation, Slow heart rate, Flushing, Dilatation of pupil, Difficulty in urination, Constipation


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Expert advice FOR RISCALM PLUS

  • You will be regularly monitored for increase in weight, blood glucose level (if you are suffering from diabetes), and for signs and symptoms of fever and infection if you are having history of low white blood cell count.
  • Children and adolescents should be carefully monitored to check the sleepiness (sedative) effects of risperidone.
  • Your child will be regularly monitored for measurements of height, weight, sexual maturation, monitoring of menstrual functioning, and other potential prolactin-related effects.
  • Use with caution if you have history of fits (seizures).
  • If you are a men taking risperidone, you may be at a risk of getting priapism (persistent and painful erection of the penis). Seek for medical advice if you develop such signs and symptoms.
  • Use risperidone with caution in patients with heart disorders such as heart failure, heart attack, conduction abnormalities, dehydration or decrease in blood volume.
  • Do not take risperidone if you develop tardive dyskinesia (twitching or jerking movements that you cannot control in your face, tongue, or other parts of your body). 
  • Do not consume alcohol along with risperidone as it may worsen the side effects.
  • Do not take risperidone along with furosemide, as it may lead to death.
  • Tell your doctor if you are or planning to become pregnant or are breastfeeding.

Frequently asked questions FOR RISCALM PLUS



Is risperidone addictive/controlled substance?
No. Risperidone is neither addictive nor controlled substance


Is risperidone an antipsychotic/ sedative/SSRI/ neuroleptic?
Risperidone is an atypical antagonist which may show sedative effects. It has affinity towards serotonin. Few studies have shown that risperidone induces neuroleptic malignant syndrome


Is risperidone used for anxiety?
No. Risperidone is not used for anxiety

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Is risperidone a benzo?
No. Risperidone is not a benzo


Is risperidone the same as risperdal?
Yes. Risperdal is a brand name of drug risperidone


Can I take risperidone with nyquil?
No. Taking risperidone with Nyquil (dextromethorphan and doxylamine) may increase the side effects such as drowsiness, blurred vision, dry mouth, heat intolerance, flushing, decreased sweating, difficulty urinating, abdominal cramping, constipation, rapid heartbeats, confusion, and memory problems


Can I take vicodin/tramadol/ ambien/diazepam with risperidone?
Using Vicodin (acetaminophen and hydrocodone), Ambien (zolpidem) or diazepam together with risperidone may increase side effects such as dizziness, drowsiness, and difficulty concentrating. Tramadol may increase the risk of seizures when given with risperidone


Can I take ibuprofen/ trazodone/melatonin/ Tylenol with risperidone?
Yes. Taking ibuprofen/ trazodone/melatonin/ Tylenol (acetaminophen) with risperidone does not cause any harmful effects. Please follow your doctor's advice regarding its use


Does risperidone cause depression/ weight loss/ high prolactin levels/ weight gain/ lower blood pressure/ make you high or drowsy/ help you sleep?
These side effects are commonly observed with risperidone use. Stop taking risperidone and consult your doctor immediately if you experience any of these symptoms.



Does trihexyphenidyl get you high/ cause weight gain?
Trihexyphenidyl doesn't make you feel high. It does not cause weight gai


Does trihexyphenidyl work?
Trihexyphenidyl works by blocking the action of a chemical called acetylcholine on the nerves which results in relaxing of smooth muscles; thereby, reducing the rigidity of muscle spasm (sudden involuntary contraction of a muscle or group of muscles), tremor (uncontrolled shaking) and excessive salivation associated with Parkinson's disease.


Content on this page was last updated on 03 February, 2017, by Dr. Varun Gupta (MD Pharmacology)