Q. What is Razona extended-release(ER) tablet?
Razona extended release (ER) means the pill is formulated in such a manner that the drug is released slowly over time and blood levels of a drug are more consistent. This has the advantage of taking fewer pills and also with a lesser gastrointestinal side effect.
Q. Do Razona and trimetazidine act in the same way?
No. Both Razona and trimetazidine are used for the treatment of angina but they work by a different mechanism. Razona works by blocking late sodium current channel during ischemia and thereby lessens the intracellular sodium and calcium overload. This relaxes heart muscles and decreases the oxygen requirement. This helps to prevent angina. Trimetazidine works by improves glucose utilisation of heart cells through inhibition of fatty acid metabolism.
Q. What is the effect of Razona in patients with coronary artery disease?
The researcher has studied Razona in patients with non-ST-elevation coronary artery disease. It did not reduce the risk of death or recurrent heart attacks in patients, but it improves angina symptoms. It is approved for use in angina.
Q. Can I use rivaroxaban with Razona?
Yes. Combining these medications can increase the blood levels of rivaroxaban and increase the risk of serious bleeding complications. You may need a dose adjustment. If you have kidney disease, you should inform your doctor before using rivaroxaban together with Razona.
Q. Can I take Razona for type 2 diabetes?
No. Razona is not approved for treatment of type 2 diabetes. Study have demonstrated its ability to decrease HbA1c (glycosylated haemoglobin) in patients with or without diabetes. This property may be useful in the treatment of patients having diabetes mellitus and angina.
Q. Can I take Razona with quetiapine?
No. Using Quetiapine with Ranolazine can increase the risk of an irregular heart rhythm that may be serious and potentially life-threatening.
Q. Is Razona good for the heart?
Razona is used in a disease of the heart known as angina. It has been shown to improve exercise-induced chest pain and severity of angina.
Q. Are any alternatives to Razona?
Yes, there are alternative to Razona e.g.Ivabradine, nicorandil and trimetazidine for effective control of anginal symptoms.
Q. Can I take Razona with atorvastatin?
Yes. Razona may significantly increase the blood levels of atorvastatin. This can increase the risk of side effects such as liver damage and the breakdown of skeletal muscle tissue. It can be used with atorvastatin but with dose limitation (atorvastatin) and appropriate clinical monitoring. In some cases, this can cause kidney damage and even death.
Q. Can I use Razona for the treatment of atrial fibrillation?
No. Razona is not approved for treatment of atrial fibrillation (AF). The researcher has demonstrated, its usefulness in patients with Atrial Fibrillation(AF) and in nonsustained ventricular tachycardia (VT) in the experimental model.
Q. Is Razona a beta blocker?
No, Razona is not a beta blocker. It is used in the treatment of angina.
Q. Can I take Razona with haloperidol?
No. Razona should not be used with haloperidol. It may increase the risk of an irregular heart rhythm that may be serious and potentially life-threatening.
Q. Is Razona effective in arrhythmia?
No. Razona is not approved for use in any of arrhythmia. The researcher has demonstrated, its usefulness in patients with Atrial Fibrillation(AF) and in nonsustained ventricular tachycardia (VT) in the experimental model.
Q. What are the contraindications to Razona?
Razona is contraindicated in patients with liver damage (cirrhosis). It should not be given with medicine like ketoconazole, itraconazole, clarithromycin, nefazodone, nelfinavir, ritonavir, indinavir, saquinavir, carbamazepine, phenobarbital, phenytoin, rifampin.
Q. Can I use Razona for the treatment of diastolic heart failure?
No. Razona is not used in the treatment of diastolic heart failure. It is used in the treatment of angina.