R2 20mg Tablet

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Abbott

Composition for R2 20mg Tablet

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Primarily used for

Potentiallyunsafewith
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Alcohol
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Pregnancy
279.8
₹27.98/Tablet
10 tablets in 1 strip
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Medicine Overview of R2 Tablet

uses

Uses of R2 Tablet

R2 20mg Tablet is used in the treatment of increased cholesterol, increased triglycerides and increased LDL levels.
uses

Side effects of R2 Tablet

Common

Musculoskeletal (bone, muscle or joint) pain, Allergic reaction, Headache, Nausea, Dyspepsia, Nasopharyngitis, Increased liver enzymes, Increased creatine phosphokinase (CPK) level in blood, Diarrhoea, Flatulence, Constipation, Joint swelling, Increased glucose level in blood.

uses

How to use R2 Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. It can be taken with or without food, but it is better to take R2 20mg Tablet at a fixed time.

How R2 Tablet works

R2 20mg tablet is a cholesterol-lowering medicine (statins). It works by blocking an enzyme (HMG-CoA-reductase) that is required in the body to make cholesterol. It thus lower "bad" cholesterol (LDL), triglycerides and raise "good" cholesterol (HDL).

In Depth Information on R2 Tablet

Expert advice for R2 Tablet

  • Inform your doctor if you have muscle pain, cramps, weekness, tiredness or dark coloured urine while taking R2.
  • R2 may increase blood sugar levels. Your doctor may ask to monitor your blood sugar levels regularly.
  • Inform your doctor if you regularly drink a large amount of alcohol.
  • Inform your doctor if you are pregnant or planning to conceive or breastfeeding.
  • Inform your doctor if you have ever been diagnosed with kidney or liver problems.
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Warnings
Special precautions for R2 20mg Tablet
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Alcohol
CAUTION
Taking alcohol with Rosuvastatin increases the chances of liver dysfunction.
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Pregnancy
CAUTION
R2 20mg Tablet is highly unsafe to use during pregnancy.

Human and animal studies have shown significant adverse effects on the foetus. Please consult your doctor.
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Lactation
CAUTION
R2 20mg Tablet is probably usafe to use during lactation. L
imited human data suggests that the drug could represent a significant risk to the baby.
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Driving
SAFE
R2 20mg Tablet does not usually affect your ability to drive.
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Kidney
CAUTION
R2 20mg Tablet should be used with caution in patients with kidney disease. Dose adjustment of R2 20mg Tablet may be needed. Please consult your doctor.

Use of R2 20mg Tablet is not recommended in patients with severe kidney disease.
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Liver
CAUTION
R2 20mg Tablet should be used with caution in patients with liver disease. Dose adjustment of R2 20mg Tablet may be needed. Please consult your doctor.

Use of R2 20mg Tablet is not recommended in patients with severe liver disease and active liver disease.
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Severely interacts with other drugs like
Flutis 150mg Tablet, Onitraz 100mg Capsule, AF 150mg Tablet DT, Flugee 150mg Tablet

Missed Dosageuses

If you miss a dose of Rosuvastatin, skip it and continue with your normal schedule. Do not double the dose.

Patient Concerns

Frequently asked questions for R2 20mg Tablet

Frequently asked questions for Rosuvastatin

Clinical studies have shown that R2 is well tolerated in patients even after long-term use and is relatively safe. However, it has its own side effects and hence should only be used in the dose, and for the duration as advised by your doctor.
No, R2 is not a blood thinner. It is a lipid-lowering medicine and belongs to a group of medicines known as HMG-CoA reductase inhibitors.
Q. Is R2 better than atorvastatin?
In clinical studies, R2, when compared to an equal dose of atorvastatin, had a better lipid lowering effect. There was no significant difference in the safety profile of both the drugs.
Q. Is R2 same as simvastatin?
R2 and simvastatin are different drugs. However, they belong to the same group of drugs called HMG-CoA reductase inhibitor and both are used for lowering high lipid levels in the blood.
Q. Can I take R2 with ibuprofen?
R2 can be safely taken with ibuprofen. There are no reported drug-drug interactions or harmful effects when they are used together.
Q. Can I take R2 with magnesium?
Magnesium taken as a health supplement is not known to have any interaction with R2. However, taking the drug with antacids containing magnesium hydroxide can decrease the amount of R2 in the body by half and the effectiveness of R2 may decrease. So, antacids should be taken at least two hours after taking R2.
Q. Can I take R2 with ranitidine?
R2 can be taken with ranitidine. There are no reported drug-drug interactions or harmful effects when they are used together.
Q. Can you take R2 with levothyroxine?
Levothyroxine is not known to have any interaction with R2. Consult your doctor before taking the two medicines together as the high cholesterol could be due to hypothyroidism for which you are given levothyroxine. R2 should be used with caution in patients having high cholesterol due to hypothyroidism especially if the underlying disease is not properly treated.
R2 is not known to have any effect on weight. Weight loss with this drug has only been reported by some patient and is seen in some animal studies. But there are no human research studies to show weight loss with R2. However, if you notice any change in body weight during therapy, consult your doctor as it could be due to some underlying condition that needs attention.
R2 use is seen to be associated with an increase in blood sugar levels in clinical studies. The increase is similar to as seen in a diabetic patient and you may need treatment for the same. Consult your doctor before taking R2 if you are a diabetic.
R2 use is not associated with erectile dysfunction. If you have this problem, this could be due to some other underlying condition and you may need to consult a doctor.
Yes, R2 can lower triglyceride levels. It also lowers total cholesterol and LDL cholesterol levels and increase the HDL levels.
R2 is not known to cause weight gain. However, if you notice any change in body weight during therapy, consult your doctor as there could be some other underlying condition that needs attention like fluid overload (water retention) in the body due to some heart, kidney or liver disease.
R2 is not known to cause dry mouth. Common side effects seen with its use are musculoskeletal (bone, muscle or joint) pain, allergic reaction, headache, nausea, dyspepsia, nasopharyngitis, increased liver enzymes, increased creatine phosphokinase (CPK) level in blood, diarrhea, flatulence, constipation, joint swelling and increased glucose level in blood
R2 is not known to increase blood pressure. Common side effects seen with its use are musculoskeletal (bone, muscle or joint) pain, allergic reaction, headache, nausea, dyspepsia, nasopharyngitis, increased liver enzymes, increased creatine phosphokinase (CPK) level in blood, diarrhea, flatulence, constipation, joint swelling and increased glucose level in blood.
R2 use is not associated with hair loss. Common side effects seen with its use are muscle damage, musculoskeletal (bone, muscle or joint) pain, allergic reaction, headache, nausea, dyspepsia, nasopharyngitis, increased liver enzymes, increased creatine phosphokinase (CPK) level in blood, diarrhea, flatulence, constipation, joint swelling and increased glucose level in blood.
Muscle pain is one of the common side effects associated with R2 use. Be careful and look for any muscle symptoms like muscle pain, tenderness, or weakness or dark colored urine. If you have any of these symptoms, stop taking R2 and immediately inform your doctor. These symptoms could be due to muscle breakdown and release of muscle proteins into the blood stream (this condition is known as rhabdomyolysis) and this can lead to problems like kidney failure.
Yes, R2 can be taken with grapefruit juice. No drug-drug interactions or any harmful effects have been reported when they are used together.
Q. Can I take R2 with clopidogrel?
R2 can be taken along with clopidogrel. R2 does not interfere with the antiplatelet action of clopidogrel.However, a high dose of clopidogrel can increase the R2 blood concentration by 2-fold causing more chances of the side effects, so a dose adjustment for R2 may be needed.
Q. Which is more beneficial in the management of cardiovascular diseases - R2 or atorvastatin?
Both R2 and Atorvastatin are seen to be equally safe and effective in lowering bad cholesterol, increasing good cholesterol and possibly reversing plaque formation when given in their maximum doses. However, R2 is seen to decrease LDL cholesterol better than Atorvastatin in many studies but the difference was not significant in terms of slowing disease progression and improving clinical outcomes.
Yes, R2 can be taken along with vitamin D. No drug-drug interactions or any harmful effects have been reported when they are used together.
Q. Can the use of R2 increase vitamin D levels in your body?
R2 has shown to increase vitamin D levels in many clinical research studies. In some studies, the rise has been up to three times the base level. However, the mechanism by which it increases the vitamin D levels is still not clear.
R2 acts by blocking an enzyme which is important for cholesterol synthesis in our body. The activity of this enzyme is more at night time, so, it is advisable to take R2 in the evening hours after a meal or just before going to bed to have maximum effect. However, R2 being a longer acting statin can be taken at any time of day.
Q. Would a combination of ezetimibe and simvastatin be better than R2 alone?
Ezetimibe and Simvastatin are used to treat high cholesterol and triglyceride levels along with a proper diet. Together they are useful in preventing conditions like heart attack and stroke by delaying the formation of plaques in the blood vessels. In one of the clinical studies, ezetimibe and simvastatin combination was found to be better than R2 alone in decreasing the LDL-cholesterol, other non-HDL-cholesterol, and total cholesterol especially in high-risk patients (uncontrolled hyperlipidemia or obese patients).
Q. How is R2 different from lovastatin?
Both R2 and lovastatin belong to the same class of drugs and are used to manage high blood cholesterol levels. However, R2 is more effective in lowering blood cholesterol and its action stays for a long time and it can be taken at any time of the day whereas lovastatin is to be taken only in the evening. The dose of lovastatin needs adjustment in patients with the moderate-to-severe renal disease while a dose of lovastatin needs adjustment only in severe renal disease.
Q. How is R2 better than pravastatin?
Both R2 and pravastatin belong to the same class of drugs and are used to manage high blood cholesterol levels. However, R2 is more effective in lowering blood cholesterol and its action stays for a long time and it can be taken at any time of the day whereas pravastatin is to be taken only in the evening. Also, R2 can be taken with or without food while food interferes with the absorption of pravastatin.
Q. Can I take R2 with quetiapine?
Yes, R2 can be used along with quetiapine. No drug-drug interactions or any harmful effects have been reported when they are used together.
Q. Can I take R2 with coenzyme q10?
R2 can be taken with coenzyme Q10. According to some clinical studies, coenzyme Q10 can help in decreasing the muscle damage caused by R2 while some of the studies say that it has no role in preventing muscle damage. Also, R2 has been thought to decrease the levels of coenzyme Q10. So, it is advised sometimes to use coenzyme Q10 along with R2 to decrease its side effects.
Q. Can I take R2 with diphenhydramine?
Yes, R2 can be used along with diphenhydramine. No drug-drug interactions or any harmful effects have been reported when they are used together.
Q. Can I take R2 with pantoprazole?
Yes, R2 can be used along with pantoprazole. No drug-drug interactions or any harmful effects have been reported when they are used together.
Q. Is it safe to take R2 with gemfibrozil?
Concomitant use of R2 with gemfibrozil should be avoided. Gemfibrozil can increase the blood levels of R2 and damage your muscles. If you are taking both the drugs, be careful and look for any muscle symptoms. Inform your doctor if you have muscle pain, tenderness, or weakness or dark colored urine.
Q. What is the benefit of taking R2 with ezetimibe?
R2, when used with ezetimibe, helps in a better decrease in LDLcholesterol and triglyceride levels compared to R2 alone and without any increase in side effects. This combination is very beneficial in high-risk cardiovascular disease patients as its use can decrease the risk of atherosclerotic plaque rupture and heart attack. However, ezetimibe can increase the blood levels of R2, so a dose adjustment may be needed when they are used together.
R2 is not approved for use in the treatment of cancer. Some research studies have shown that R2 can stop the growth of cancer cells and when given after surgery, it can kill the remaining cancer cells if any and can help in preventing cancer from coming back. Clinical research studies are going on for its use in patients of colon cancer as it may prevent the formation of polyps and the recurrence of colon cancer but this use is still under research and not approved.
R2 is not indicated for the treatment of weight loss (obesity). Weight loss with this drug has only been reported by some patient and is seen in some animal studies. But there are no human research studies to show weight loss with R2.
Yes, R2 is very useful in the treatment of dyslipidemia, a lipid disorder with very high or very low lipid levels in the blood. Most common lipid disorder is hyperlipidemia in which the patient has high levels of bad lipids (low-density lipoprotein, or LDL) and triglycerides, and low levels of good lipids (high-density lipoprotein, or HDL) in the blood. R2 along with exercise and a low-fat diet decreases the LDL levels and increases the HDL levels and decrease the risk of heart disease and stroke on long-term use.
R2 is seen to be useful in preventing new episodes of ischemic stroke in the brain. Ischemic stroke occurs when there is a blockage of the blood vessel of the brain decreasing blood flow to a particular area of the brain. This blockage occurs due to plaque formation (deposition in the arteries where cholesterol combines with fat, calcium, and fibrin). R2 decreases the chances of plaque formation by lowering the cholesterol levels in the body and hence low-fat the risk of new episodes of stroke. It is not routinely prescribed for the prevention of hemorrhagic stroke.
R2 is found to be useful in preventing new episodes of ischemic stroke in the brain. Ischemic stroke occurs when there is a blockage of the blood vessel of the brain decreasing blood flow to a particular area of the brain. This blockage occurs due to plaque formation (deposition in the arteries where cholesterol combines with fat, calcium, and fibrin). R2 decreases the chances of plaque formation by lowering the cholesterol levels in the body and hence lowers the risk of new episodes of stroke. It is not routinely prescribed for the prevention of hemorrhagic stroke.
Q. Can I take R2 with Febuxostat?
R2 can be taken with febuxostat. R2 is used to lower bad cholesterol and Febuxostat is used to lower uric acid levels in patients with gout. Many patients of high cholesterol levels also have high uric acid levels. There are no human studies available on this interaction. However, animal research shows that when given together, febuxostat can increase the blood levels of R2 causing a higher risk of its side effects like muscle pain and muscle damage. So, a dose adjustment of R2 may be needed when given along with febuxostat.
R2 is not used in the treatment of sepsis associated Acute respiratory distress syndrome (ARDS). ARDS is a condition in which there is inflammation of the lung leading to severe organ failure and this could be due to an underlying infection (sepsis). It is seen in some human research studies that there is no useful effect of R2 in treatment of the sepsis associated ARDS. Rather, it may cause damage to liver and kidney in these patients.
Q. Is there any benefit of taking vitamin C with R2?
R2 can be safely taken with vitamin C. There are no drug-drug interactions reported between the two and no harmful effects have been seen. R2 is a cholesterol lowering agent used to treat hyperlipidemia. Vitamin C also acts as an anti-oxidant and few studies have shown that vitamin C can also help to lower bad cholesterol. So, using them together can actually be beneficial to lower the blood cholesterol levels.
Q. Can I take calcium supplements with R2?
R2 should not be taken with calcium supplements as calcium can decrease its absorption and hence lowers the blood levels of R2. This can lead to a decrease in efficacy of R2 to lower blood cholesterol levels. To avoid this effect, there should be a gap of at least 2 hours between the two medicines.
No, R2 is not a narcotic substance. It's a prescription medicine and is available on providing a valid prescription by a doctor.
No, R2 is not a nitrate. It is a lipid-lowering medicine and belongs to a group of medicines known as HMG-CoA reductase inhibitors.
No, R2 is not a diuretic. It is a lipid-lowering medicine and is used to lower increased levels of cholesterol and triglycerides in the blood. A diuretic is a medicine, which removes excess water and electrolytes from the body through urine.
No, R2 is not a beta blocker. It is a lipid-lowering medicine and is used to lower increased levels of cholesterol and triglycerides in the blood.
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