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MD Pharmacology, MBBS
Last updated
25 Nov 2025 | 10:54 PM (IST)

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Pyrione Forte Tablet

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Product introduction

Pyrione Forte Tablet is a combination medicine used in the treatment of nausea or vomiting during pregnancy. It blocks signals to reach the brain that trigger the feeling of nausea and vomiting.

Pyrione Forte Tablet is taken with or without food in a dose and duration as advised by the doctor. The dose you are given will depend on your condition and how you respond to the medicine. You should keep taking this medicine for as long as your doctor recommends. If you stop treatment too early your symptoms may come back and your condition may worsen. Let your healthcare team know about all other medications you are taking as some may affect, or be affected by this medicine.

The most common side effects are dryness in the mouth, constipation, and lightheadedness. Most of these are temporary and usually resolve with time. Contact your doctor straight away if you are at all concerned about any of these side effects. This medicine can also cause dizziness and sleepiness, so do not drive or do anything that requires mental focus until you know how this medicine affects you. Avoid drinking alcohol while taking this medicine as it can worsen your sleepiness.


Benefits of Pyrione Forte Tablet

In Treatment of Nausea and vomiting in pregnancy

Pyrione Forte Tablet blocks the action of chemicals in the body that can make you feel or be sick during pregnancy. This medicine helps you cope up with nausea or vomiting that occurs due to hormonal changes during pregnancy and helps you complete the term without much discomfort. It also contains nutritional supplements that improve your baby’s immune system, enhance the baby’s brain development and also help reduce nausea and vomiting during pregnancy.

Side effects of Pyrione Forte Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Pyrione Forte

  • Sleepiness
  • Dizziness
  • Fatigue
  • Dryness in mouth
  • Constipation

How to use Pyrione Forte Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Pyrione Forte Tablet should be taken with or after food.

How Pyrione Forte Tablet works

Pyrione Forte Tablet is a combination of three medicines: doxylamine, vitamin B6 (pyridoxine) and folic acid, which treats nausea and vomiting associated with pregnancy.

Safety advice

Alcohol
UNSAFE
Do not drink alcohol while you are taking this medicine. Pyrione Forte Tablet may cause excessive drowsiness when taken with alcohol.
Pregnancy
SAFE IF PRESCRIBED
Pyrione Forte Tablet is safe to use during pregnancy. Most studies have shown low or no risk to the developing baby.
Breast feeding
CONSULT YOUR DOCTOR
Pyrione Forte Tablet may be unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby. It should be used only if the expected benefit outweighs the potential risk. Please consult your doctor.
Driving
CONSULT YOUR DOCTOR
It is not known whether Pyrione Forte Tablet alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react. Please consult your doctor.
Kidney
CONSULT YOUR DOCTOR
There is limited data available on the use of Pyrione Forte Tablet in patients with kidney disease. Please consult your doctor.
Liver
CONSULT YOUR DOCTOR
There is limited data available on the use of Pyrione Forte Tablet in patients with liver disease.

What if you forget to take Pyrione Forte Tablet?

If you miss a dose of Pyrione Forte Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.
Pyrione Forte Tablet
₹4.18/Tablet
Vomilast -OD Tablet
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₹11.3/tablet
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Doxinate Forte Tablet
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₹13.07/tablet
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Vominos Tablet
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₹6.01/tablet
44% costlier
Cor NVP OD 20mg/20mg/5mg Tablet
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₹7.8/tablet
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Sysfol-NVP Tablet
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₹7.85/tablet
88% costlier

Quick tips

  • Pyrione Forte Tablet helps treat nausea and vomiting in pregnant women whose symptoms did not improved using diet and lifestyle changes. 
  • Take it on an empty stomach with a glass of water.
  • It may cause dizziness. Do not drive or do anything requiring concentration until you know how it affects you.
  • Do not take it with other sedating medications such as cough and cold medications as the combination could worsen dizziness leading to falls or other accidents

Fact Box

Habit Forming
No
Therapeutic Class
GASTRO INTESTINAL

Patient concerns

Not eating. Vomiting wt we do.
Dr. Megha Tuli
Obstetrics and Gynaecology
Avoiding fluids including tea and water right early in the morning will help. Ginger also helps with the nausea and vomiting of pregnancy.
She miss her period since last 12 days & upt is postitive . Patient having abdominal pain , vomiting , nausea , weakness , fainting .
Dr. Suman Rao
Obstetrics and Gynaecology
These are the normal symptoms of pregnancy. She can take treatment for nausea and vomiting after consulting a Gynae

FAQs

What are the instructions for storage and disposal of Pyrione Forte Tablet?

Keep this medicine in the container or the pack it came in, tightly closed. Store it at as mentioned on the pack or label. Dispose of the unused medicine. Make sure it is not consumed by pets, children and other people.

Can I take a higher than the recommended dose of this medicine?

No, taking a higher than the recommended dose of Pyrione Forte Tablet can cause increased side effects. If you are experiencing increased severity of nausea or vomiting, which is not relieved by the recommended doses, please consult your doctor for re-evaluation.

Can the use of Pyrione Forte Tablet cause drowsiness or sleepiness?

Yes, one of the common side effects of Pyrione Forte Tablet is drowsiness. Do not drive, operate heavy machinery or engage in other activities that need your full attention. Do not drink alcohol or take any medicines that may depress the central nervous system like cough and cold medicines, certain pain medicines, and medicines that help you sleep, while you are taking Pyrione Forte Tablet. Severe drowsiness can happen or it can become worse and cause falls or accidents.

Can the use of Pyrione Forte Tablet cause dry mouth?

Yes, the use of Pyrione Forte Tablet can cause dry mouth. If you experience dry mouth, drink plenty of water. Take regular sips during the day and keep some water by your bed at night. Try to avoid foods that are acidic (like lemons), spicy and salty.

Can a pregnant woman take Pyrione Forte Tablet?

Yes, it is safe to take Pyrione Forte Tablet in pregnant women. In fact, this medicine is used to treat nausea and vomiting in pregnant women. It is mainly recommended to those women whose symptoms have not improved after changing their diet or using other non-medicine treatments.

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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

  1. Doxylamine succinate and pyridoxine hydrochloride. Blainville, Québec: Duchesnay Inc.; 1976 [revised Nov. 2016]. [Accessed 12 Apr. 2019] (online) Available from:External Link
  2. DailyMed. Doxylamine succinate and pyridoxine hydrochloride. [Accessed 12 Apr. 2019] (online) Available from:External Link
  3. ScienceDirect. Vitamin B6. [Accessed 12 Apr. 2019] (online) Available from:External Link
  4. DailyMed. Pyridoxine hydrochloride. [Accessed 12 Apr. 2019] (online) Available from:External Link

Marketer details

Name: Zeelab Pharmacy Pvt Ltd
Address: 913, D-104, Pitampura, Delhi-110034
Country of origin: India
Expires on or after: August, 2027

A licensed vendor partner from your nearest location will deliver Pyrione Forte Tablet. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.

In case of any issues, contact us

Email ID: [email protected]
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India

MRP45  7% OFF
41.8
Inclusive of all taxes
10.0 tablets in 1 strip
New GST benefit included in this MRP, may differ from label
Get by Tuesday, 2 December
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