Author Details
Written By
BCMAS, Pharm.D
Reviewed By
MD (Pharmacology), MBBS
Last updated:
18 Feb 2020 | 05:25 PM (IST)
Want to know more?
Read Our Editorial Policy
Have issue with the content?
Report Problem

Pyralfin 25 mg/500 mg Tablet


Overview

Introduction

Pyralfin 25 mg/500 mg Tablet is a combination medicine that is prescribed to treat malaria. It fights against the infection by preventing the growth of the parasites inside the body.

Pyralfin 25 mg/500 mg Tablet is a prescription medicine. It is to be taken with food and take it at a fixed time regularly. Take the medicine in the dose and duration advised by your doctor. Do not consume more than the recommended dose, as this may have harmful effects on your body. A missed dose should be taken as soon as you remember. The course of the treatment should be completed for better efficacy.

Some common side effects of this medicine are headaches, diarrhea, nausea, vomiting, weakness, indigestion, etc. You may also feel dizzy, thus it is advised not to drive or operate machinery. To overcome dizziness you should drink plenty of fluid. If any of the side effects get aggravated, contact your doctor immediately.

Before taking this medicine, you should tell your doctor if you are taking any medication for any health conditions. Pregnant or breastfeeding women should also consult with their doctor before taking it. Avoid drinking alcohol as it can cause excessive drowsiness with this medicine.

Uses of Pyralfin Tablet

Side effects of Pyralfin Tablet

Common
  • Nausea
  • Vomiting
  • Diarrhea
  • Fatigue
  • Feeling of fullness
  • Dizziness
  • Headache
  • Mouth sore
  • Skin rash

How to cope with side effects?

The occurrence of side effects varies from person to person. The following are a few ways of dealing with some of the common side effects. However, consult your doctor if these persist.

  • Coping with Nausea
    You can help yourself by eating small, frequent meals rather than large ones and drinking plenty of fluids. Eat slowly. Avoid fatty, fried, spicy and very sweet foods. Eat cold or slightly warm food if the smell of cooked or cooking food makes you feel sick. Get plenty of fresh air. You could also try chewing ginger or drinking ginger tea. Eat bananas to replace potassium in your blood which can drop if you are sick (vomit). Use oral rehydration salts to replace vitamins and minerals lost through being sick. There are some medicines that can help you stop from feeling sick. Speak to your doctor if your condition does not improve.
  • Coping with Vomiting
    You can help yourself by eating small, frequent meals rather than large ones and drinking plenty of fluids. Eat slowly. Avoid fatty, fried, spicy and very sweet foods. Eat cold or slightly warm food if the smell of cooked or cooking food makes you feel sick. Get plenty of fresh air. You could also try chewing ginger or drinking ginger tea. Eat bananas to replace potassium in your blood which can drop if you are sick (vomit). Use oral rehydration salts to replace vitamins and minerals lost through being sick. There are some medicines that can help you stop feeling sick. Speak to your doctor if your condition does not improve.
  • Coping with Diarrhea
    Keep up your intake of fluids and electrolytes (sugars and salts) to avoid getting dehydrated. Eat less fiber (avoid raw fruits, fruit juice and vegetables). Talk to your doctor about possible medication to manage diarrhea. Ask about reducing the dosage of your drug or other suitable treatments.
  • Coping with Dizziness
    This is usually short-lived and should go away within a few days. If this happens, stop what you are doing and sit or lie down until you feel better. Lying still in a dark, quiet room may help reduce the spinning feeling. Sleep with your head slightly raised on two or more pillows. Get up slowly from a lying or sitting position. Get plenty of rest and try to relax as being anxious can make it worse. Try taking this medicine at bedtime to reduce the symptoms. Drinking plenty of water and ginger tea may also help. Avoid alcohol, caffeine and smoking as it will make you feel worse. Avoid driving or using tools or machinery until you feel better.
  • Coping with Headache
    Make sure you rest and drink plenty of fluids. Rest in a quiet, dimly lit room. Do not sleep more than you normally would. Do not strain your eyes (for example by looking at a screen). Do not drink alcohol. Headaches are usually temporary and usually go away with time. But, if they last longer or get worse, ask your doctor to recommend a painkiller.
  • Coping with Mouth sore
    Avoiding things that irritate your ulcer will help speed up the healing process, reduce pain, and reduce its chances of coming back. Keep your mouth hydrated by drinking plenty of fluids and clean by rinsing it regularly with warm and slightly salted water. Eat softer foods and drink cold drinks through a straw. Try to avoid foods that are very hot, spicy, sour (acidic) or salty and rough, crunchy foods like potato chips or toast. Do not use chewing gum and do not smoke or drink alcohol. Keep your mouth clean using a soft-bristled toothbrush and get regular dental check-ups. Consult your doctor if your condition does not improve or lasts more than a few days.
  • Coping with Skin rash
    There are many treatments for a wide range of skin problems. Avoid hot showers or baths because hot water can irritate the skin. Make sure to pat dry your skin after a bath or shower. Do not rub or scratch the affected area. Leave the skin exposed to the air as much as possible. Do not use perfumed soaps or deodorants. Water containing chlorine can make most skin problems worse, so avoid swimming. Avoid spicy foods, alcohol, tobacco smoke and caffeine as it may also make itching worse. Avoid excessive sun exposure. Always use sunscreen and protective clothing when outdoors. Moisturizers can be used regularly to soothe and hydrate the affected area. If it does not get better within a week, speak to a pharmacist or doctor.

How to use Pyralfin Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Pyralfin 25 mg/500 mg Tablet is to be taken with food.

How Pyralfin Tablet works

Pyralfin 25 mg/500 mg Tablet is a combination of two medicines: Pyrimethamine and Sulphadoxine which treat malaria. Pyrimethamine is an antiparasitic medicine which works by increasing the levels of haeme in the blood, a substance toxic to the malarial parasite. This kills the parasite and stops the infection from spreading. Sulphadoxine is an antibiotic which stops the bacteria from producing folic acid, a nutrient required for bacterial multiplication.

Safety Advice

Alcohol
CAUTION
Caution is advised when consuming alcohol with Pyralfin 25 mg/500 mg Tablet. Please consult your doctor.
Pregnancy
CONSULT YOUR DOCTOR
Pyralfin 25 mg/500 mg Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breastfeeding
CONSULT YOUR DOCTOR
Pyralfin 25 mg/500 mg Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Driving
CONSULT YOUR DOCTOR
It is not known whether Pyralfin 25 mg/500 mg Tablet alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react.
Kidney
CAUTION
Pyralfin 25 mg/500 mg Tablet should be used with caution in patients with kidney disease. Dose adjustment of Pyralfin 25 mg/500 mg Tablet may be needed. Please consult your doctor.
Liver
CAUTION
Pyralfin 25 mg/500 mg Tablet should be used with caution in patients with liver disease. Dose adjustment of Pyralfin 25 mg/500 mg Tablet may be needed. Please consult your doctor.

Alternate Brands

For informational purposes only. Consult a doctor before taking any medicines.
Pyralfin 25 mg/500 mg Tablet
₹1.88/Tablet
Malasulf 25 mg/500 mg Tablet
Bombay Tablet Mfg Co Pvt Ltd
₹2.2/Tablet
17% costlier
Croydoxin FM 25 mg/500 mg Tablet
Glaxo SmithKline Pharmaceuticals Ltd
₹2.36/Tablet
26% costlier
Laridox Tablet
Ipca Laboratories Ltd
₹2.49/Tablet
33% costlier
Rimodar 25 mg/500 mg Tablet
Anglo-French Drugs & Industries Ltd
₹2.6/Tablet
38% costlier
Malocide Tablet
Torrent Pharmaceuticals Ltd
₹24.98/Tablet
1232% costlier

Patient Concerns

arrow
Can we offer avil 25 mg tablet
Dr. Gopal Samdani
Paediatrics
Your question is not clear
Symptoms of malaria. High fever generally in evening Local doctor has prescribed doxcof cv
Dr. Pushkar Mani
Physician
there is no role of antibiotic in malariaplz do the test for Malaria rapid card test, and Denguefor fever paracetamol 500 mg 3 times for 3 days
arrow
Do you have any questions related to Pyralfin 25 mg/500 mg Tablet ?

User Feedback


FAQs

Q. What if I don't get better after using Pyralfin?

Inform your doctor if you don't feel better after finishing the full course of treatment. Also, inform him if your symptoms are getting worse while using this medicine.

Q. Can I stop taking Pyralfin when I feel better?

No, do not stop taking Pyralfin and complete the full course of treatment even if you feel better. Your symptoms may improve before the infection is completely cured.

Q. What if I miss my dose?

Take Pyralfin as soon as you remember it. However, do not take it if it's almost time for your next dose. Also, do not take an extra dose to make up for your missed dose.

Related Products

Disclaimer: 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover all possible side effects, drug interactions or warnings or alerts. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.
References
  1. Pyrimethamine+Sulphadoxine. Basel, Switzerland: F. Hoffmann-La Roche Ltd. [Accessed 10 Apr. 2019] (online) Available from:External Link
  2. Pyrimethamine. Research Triangle Park, North Carolina: DSM Pharmaceuticals; 2003. [Accessed 10 Apr. 2019] (online) Available from:External Link
  3. ScienceDirect. Sulphadoxine. [Accessed 10 Apr. 2019] (online) Available from:External Link
Manufacturer/Marketer Address
Lupin Ltd, 3rd floor Kalpataru Inspire, Off. W E Highway, Santacruz (East), Mumbai 400 055. India
Best Price
₹15.94
MRP18.75  Get 15% OFF
This price is valid only on the orders above ₹500
10 tablets in 1 strip
SOLD OUT

INDIA’S LARGEST HEALTHCARE PLATFORM

150M+
Visitors
25M+
Orders Delivered
1000+
Cities
Get the link to download App
Reliable

All products displayed on 1mg are procured from verified and licensed pharmacies. All labs listed on the platform are accredited

Secure

1mg uses Secure Sockets Layer (SSL) 128-bit encryption and is Payment Card Industry Data Security Standard (PCI DSS) compliant

Affordable

Find affordable medicine substitutes, save up to 50% on health products, up to 80% off on lab tests and free doctor consultations.

India's only LegitScript and ISO/IEC 27001 certified online healthcare platform
Know More About 1mgdownArrow
Access medical and health information

1mg provides you with medical information which is curated, written and verified by experts, accurate and trustworthy. Our experts create high-quality content about medicines, diseases, lab investigations, Over-The-Counter (OTC) health products, Ayurvedic herbs/ingredients, and alternative remedies.

Order medicines online

Get free medicine home delivery in over 1000 cities across India. You can also order Ayurvedic, Homeopathic and other Over-The-Counter (OTC) health products. Your safety is our top priority. All products displayed on 1mg are procured from verified and licensed pharmacies.

Book lab tests

Book any lab tests and preventive health packages from certified labs and get tested from the comfort of your home. Enjoy free home sample collection, view reports online and consult a doctor online for free.

Consult a doctor online

Got a health query? Consult doctors online from the comfort of your home for free. Chat privately with our registered medical specialists to connect directly with verified doctors. Your privacy is guaranteed.