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PROTAMINE SULPHATE 10MG INJECTION

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MRP: Rs. 95.23 for 1 vial(s) (5 ML injection each)
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Composition for PROTAMINE SULPHATE

Protamine(10 mg)

food interaction for PROTAMINE SULPHATE

alcohol interaction for PROTAMINE SULPHATE

pregnancy interaction for PROTAMINE SULPHATE

lactation interaction for PROTAMINE SULPHATE

food
alcohol
pregnancy
lactation
It can be taken with or without food, but it is better to take Protamine sulphate 10mg injection at a fixed time.
Interaction with alcohol is unknown. Please consult your doctor.
Protamine sulphate 10mg injection may be unsafe to use during pregnancy.
Animal studies have shown adverse effects on the foetus, however, there are limited human studies. The benefits from use in pregnant women may be acceptable despite the risk. Please consult your doctor.
WEIGH RISKS VS. BENEFITS
Unknown. Human and animal studies are not available. Please consult your doctor.

SALT INFORMATION for PROTAMINE SULPHATE

Protamine(10 mg)

Uses

Protamine sulphate 10mg injection is used in the treatment of heparin toxicity.

How it works

Protamine sulphate 10mg injection sulphate belongs to a class of drugs called as anticoagulants.  When Protamine sulphate 10mg injection sulphate is given in the presence of heparin (which is strongly acidic), it acts by neutralizing the effect resulting in the loss of anticoagulant activity of heparin.

Common side effects

Nausea, Allergic skin rash, Bradycardia, Low energy, Limb swelling, Vomiting, Fatigue

SUBSTITUTES for PROTAMINE SULPHATE

2 Substitutes
Sorted By
RelevancePrice
  • NEUTRAHEP 10MG INJECTION
    (5 ML injection in vial)
    Gland Pharma Limited
    Rs. 9.90/ML of injection
    generic_icon
    Rs. 49.50
    save 48% more per ML of injection
  • PROTA 10MG INJECTION
    (5 ML injection in vial)
    Samarth Life Sciences Pvt Ltd
    Rs. 8.38/ML of injection
    generic_icon
    Rs. 41.90
    save 56% more per ML of injection

Expert advice for PROTAMINE SULPHATE

  • Inform your doctor if you have undergone heart surgery, have diabetes and have received protamine insulin, are allergic to fish or have had a vasectomy or are infertile and may have antibodies to protamine, as you may be at an increased risk of experiencing allergic reaction to protamine.  
  • You will be monitored to confirm whether your blood clotting parameters are within normal limits if you are receiving multiple doses or prolonged administration of protamine.
  • You may experience sudden fall in blood pressure, breathlessness or chest and abdominal pain when receiving protamine.
  • Tell your doctor if you are pregnant or think you may become pregnant or breastfeeding.
  • Do not take if Patients is allergic to protamine sulphate or any of its ingredients.

Frequently asked questions for PROTAMINE SULPHATE

Protamine

Q.Is protamine an anticoagulant?
When administered alone, protamine has an anticoagulant effect. However, when it is given in the presence of heparin, a stable salt is formed and the anticoagulant activity of both drugs is lost

Q.Is protamine sulphate the antidote for lovenox?
Yes. Protamine sulphate is used as an antidote in the case of overdose of lovenox.

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Content on this page was last updated on 25 December, 2015, by Dr. Varun Gupta (MD Pharmacology)