Prota 10mg Injection is a medicine which is used in the treatment of heparin overdose. It neutralizes the anti-blood clotting effect of heparin and stops excessive bleeding.

Prota 10mg Injection is generally administered by a healthcare professional. You should not self administer this medicine. Inform your doctor if you have undergone heart surgery, have had a vasectomy, have diabetes, have received protamine insulin, or allergic to fish.

Using of Prota 10mg Injection can cause few side effects such as decreasing your blood pressure, slow heart rate, or reactions at the site of injection. It is important to monitor the clotting levels if you are receiving multiple doses or prolonged administration of protamine.

Uses of Prota Injection

Heparin overdose

Benefits of Prota Injection

In Heparin overdose

Heparin is an anticoagulant that prevents the formation of blood clots. Heparin overdose is when a person takes more than the normal or recommended amount of heparin. Prota 10mg Injection helps to control excessive bleeding that takes place due to this high intake of heparin. It is given as an injection by a doctor or nurse and should not be self-administered. Follow your doctor’s instructions carefully and let your doctor know about any surgeries you may have undergone in the past.

Side effects of Prota Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Prota

Decreased blood pressure
Slow heart rate
Injection site reactions (pain, swelling, redness)

How to use Prota Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Prota Injection works

Prota 10mg Injection is used to counteract the anticoagulant effect of heparin and is used to stop bleeding in patients caused by heparin.

Safety advice

Alcohol

CONSULT YOUR DOCTOR

It is not known whether it is safe to consume alcohol with Prota 10mg Injection. Please consult your doctor.

Pregnancy

CONSULT YOUR DOCTOR

Prota 10mg Injection may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

Breast feeding

SAFE IF PRESCRIBED

Prota 10mg Injection is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.

Driving

SAFE

Prota 10mg Injection does not usually affect your ability to drive.

Kidney

SAFE IF PRESCRIBED

Prota 10mg Injection is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Prota 10mg Injection may not be needed in these patients. Please consult your doctor.

Liver

SAFE IF PRESCRIBED

Prota 10mg Injection is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of Prota 10mg Injection may not be needed in these patients. Please consult your doctor.

What if you forget to take Prota Injection?

If you miss a dose of Prota 10mg Injection, please consult your doctor.\n

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.

Prota 10mg Injection

₹50.2/Injection

Neutrahep 10mg Injection

Gland Pharma Limited

₹49.8/injection

3% cheaper

Quick tips

Prota 10mg Injection helps neutralize the effect of anti-clotting medicine heparin.
It should not be used to reverse the effects of other anti-clotting medicines (anticoagulants) such as warfarin.
It should be used under medical supervision. Do not self-administer.
Inform your doctor if you experience a sudden fall in blood pressure, breathlessness, or chest and abdominal pain when receiving Prota 10mg Injection.

Fact Box

Chemical Class

Blood Factor

Habit Forming

Therapeutic Class

OTHERS

Action Class

Heparin Antagonist

Patient concerns

I am not getting pregnant while dnc has done Because there was miscarriage 4 month back

Dr. Sonu Balhara Ahlawat

Obstetrics and Gynaecology

Low molecular weight heparin

Why low molecular weight heparin used in pregnancy

Dr. Suman Rao

Obstetrics and Gynaecology

It's used only in high risk pregnancy and in certain condition like APLA to prevent miscarriage

PATIENT a heart attack before 2days luckily we saved him by taken him to the nearest hospital where a cardiologist has given complete first aid treatment he was under observation in icu for 2 days now shifted to general ward now the complication is he has hypertension and his platet counts is lower to 85000. Now my question is will the bypass surgery or angioplasty will help him to be normal as the platet count is low the cardiologist advises us not to undergo any operation Pls advice Thank you Khaja Your advice and help will be highly appreciated

Dr. Nabajit Talukdar

Cardiology

Angioplasty is better however need to see cause of low pkateletsWas he on heparin

What will happen if any child 1 year old intake overdose of iron syrup i.e. 5 ml in place of 5 drops? Also tell me the common side effect and treatment to face probkem What will happen if any child 1 year old intake overdose of iron syrup i.e. 5 ml in place of 5 drops? Also tell me the common side effect and treatment to face problem.

Dr. Gopal Bansilal Samdani

Paediatrics

Please consult Pediatric intensivist or Pediatrician expert in toxicology

User feedback

How much was the improvement?

Poor

100%

What were the side-effects while using Prota 10mg Injection?

No Side Effec*

100%

*No Side Effect

How do you take Prota Injection?

With food

100%

FAQs

Q. Is protamine sulphate the antidote for lovenox?

Yes. Protamine sulphate is used as an antidote in the case of overdose of lovenox.

Q. Is protamine an anticoagulant?

When administered alone, protamine has an anticoagulant effect. However, when it is given in the presence of heparin, a stable salt is formed and the anticoagulant activity of both drugs is lost

Related lab tests

Activated Partial Thromboplastin Time

Prothrombin Time

Want to share the information?

Disclaimer:

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 1167-68.
Medscape. Protamine. [Accessed 6 Apr. 2019] (online) Available from:
Protamine. Lake Zurich, Illinois: Fresenius Kabi; 2016. [Accessed 06 Apr. 2019] (online) Available from:
Howland MA. Antidotes in Depth. In: Hoffman RS, Howland MA, Lewin NA, et al., editors. Goldfrank's Toxicologic Emergencies. 10th ed. New York, New York: McGraw-Hill Education; 2015. [Accessed 30 Jan. 2019]. (online) Available from:
Protamine sulfate. Wrexham: Wockhardt UK Ltd.; 1991 [revised 4 May 2018]. [Accessed 6 Apr. 2019] (online) Available from:
Drugs.com. Protamine Pregnancy and Breastfeeding Warnings. [Accessed 6 Apr. 2019] (online) Available from:

Marketer details

Name: Samarth Life Sciences Pvt Ltd

Address: Samarth House, 168, Bangur Nagar, Off Link Road, Near Ayappa Temple & Kallol Kali Temple, Goregaon (W), Mumbai - 400 090.

Country of origin: India

The list of available options shown with the same composition has been prepared upon the advice of registered medical practitioners, pharmacists affiliated with TATA 1MG. TATA 1MG does not promote any pharmaceutical product of any particular company, and all recommendations are based on the medical opinion, advisories from specialist medical and pharmaceutical professionals.