Alprostadil is similar to a natural substance found in the body called prostaglandin E1 and belongs to a class of drugs known as vasodilators. It widens blood vessels and increases blood flow to the penis making it easier to have an erection.
Alprostadil is either injected into the penis or used as a urethral suppository (pellet to be placed into the urinary opening of the penis) to produce an erection before a sexual intercourse. Consult your doctor regarding administration of alprostadil.
Do not use more than one dose of alprostadil in a 24-hour period.
If you experience an erection that lasts for > 4 hours, consult your doctor immediately, as it can lead to permanent sexual problems such as impotence.
Alprostadil will not protect you or your partner from sexually transmitted diseases (e.g. AIDS) or blood-borne diseases (eg, hepatitis B). Take necessary precautions to prevent such infections.
Alprostadil will not protect your partner from pregnancy. Use a reliable and appropriate contraceptive.
You will need to have regular check-ups with your doctor while you are using alprostadil.
Do not drive or perform other possibly unsafe tasks as alprostadil may cause dizziness.
Do not drink alcohol as it worsens the side effects of alprostadil.
Tell your doctor if your partner is pregnant or breastfeeding.
Interaction with alcohol is unknown. Please consult your doctor.
WEIGH RISKS VS BENEFITS
PROSTIN VR 500MCG INJECTION is unsafe to use during pregnancy. There is positive evidence of human fetal risk, but the benefits from use in pregnant women may be acceptable despite the risk, for example in life-threatening situations. Please consult your doctor.
No information is available on the use of PROSTIN VR 500MCG INJECTION during lactation. Please consult your doctor.
Do not drive unless you are feeling well. PROSTIN VR 500MCG INJECTION may make you feel dizzy or faint. This may affect your driving ability.
There is limited information available on the use of PROSTIN VR 500MCG INJECTION in patients with kidney disease. Please consult your doctor.
There is limited information available on the use of PROSTIN VR 500MCG INJECTION in patients with liver disease. Please consult your doctor.
Prostin vr injections (with suspensions) can be stored below or at 25°C for 24 hrs. Urethral stick in unopened pouches is stored in a refrigerator (2-8oC). Prior to use you may remove them from the refrigerator and store them at room temperature (not above 30oC) for a maximum of 14 days.
Information last updated by Dr. Varun Gupta, MD Pharmacology on 16th Mar 2018.