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Prolinate Injection

Prescription Required
SALT COMPOSITION
Storage
Store below 30°C

Product introduction

Prolinate Injection is used in the treatment of schizophrenia. It may also be used to treat depression and bipolar disorder. It alters the thoughts and elevates the mood, improving the person’s ability to think, feel and behave.

Prolinate Injection is given as an injection under the supervision of a healthcare professional and should not be self-administered. Take it at the same time each day as this helps to maintain a consistent level of medicine in the body. Take this medicine in the dose and duration as advised by your doctor and if you have missed a dose, take it as soon as you remember it. Do not skip any doses and finish the full course of treatment even if you feel better. This medication mustn't be stopped suddenly without talking to your doctor as it may worsen your symptoms.

Some common side effects of this injection include dry mouth, abnormality of voluntary movements, urinary retention, constipation, and muscle rigidity. Initially, this medicine may cause a sudden drop in blood pressure when you change positions, rise slowly if you have been sitting or lying down. It may also cause dizziness and sleepiness, do not drive or do anything that requires mental focus until you know how this medicine affects you. This medicine can lead to weight gain, have a healthy balanced diet, and exercise regularly. You may also notice some injection site reactions such as pain, redness, or swelling. However, these are temporary and usually resolve on their own in some time. Please consult your doctor in case these do not subside or bother you.

Before taking it, inform your doctor if you are suffering from thyroid or kidney disease, epilepsy, Parkinson’s disease, glaucoma, or any heart disease. You should not take this medicine if you are under the influence of alcohol or any sleep-inducing, cough, and/ or allergy medication. This medicine can also lead to weight gain, eat a healthy balanced diet, avoid snacking with high-calorie food, and exercise regularly.

Benefits of Prolinate Injection

In Treatment of Schizophrenia

Schizophrenia is a mental disorder in which a person’s thinking ability, feelings, and behavior become abnormal. Prolinate Injection helps restore the chemical imbalances in the brain that are responsible for such changes. It improves thoughts, behavior and enhances the quality of life.

In Treatment of Depression

Prolinate Injection helps in maintaining the balance of certain chemicals in the brain that affect mood and behavior. This improves your mood, relieves anxiety, tension, helps you sleep better, and increases your energy levels. Prolinate Injection prevents extreme mood changes and helps you feel less agitated. You may experience fewer episodes of depression and low mood.

In Treatment of Bipolar disorder

Prolinate Injection works to restore the normal balance of nerve activity in your brain. It can help prevent extreme changes in mood and help you feel less agitated. You may experience fewer episodes of low mood. It can take several weeks for this medicine to work and you may still feel low during this time. You should continue to eat well and keep fit to reduce symptoms of bipolar disorder.

Side effects of Prolinate Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Prolinate

  • Abnormality of voluntary movements
  • Constipation
  • Dryness in mouth
  • Increased prolactin level in blood
  • Injection site reactions (pain, swelling, redness)
  • Muscle stiffness
  • Orthostatic hypotension (sudden lowering of blood pressure on standing)
  • Sleepiness
  • Tremors
  • Urinary retention
  • Weight gain

How to use Prolinate Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Prolinate Injection works

Prolinate Injection is a typical antipsychotic. It works by blocking the action of dopamine, a chemical messenger in the brain that affects thoughts and mood.

Safety advice

Alcohol
UNSAFE
Prolinate Injection may cause excessive drowsiness with alcohol.
Pregnancy
CONSULT YOUR DOCTOR
Prolinate Injection may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breast feeding
CONSULT YOUR DOCTOR
Prolinate Injection is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
If Prolinate Injection is given, monitor the baby for excessive sleepiness.
Driving
UNSAFE
Prolinate Injection may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Caution is advised when driving or operating machinery.
Kidney
CONSULT YOUR DOCTOR
There is limited information available on the use of Prolinate Injection in patients with kidney disease. Please consult your doctor.
Liver
CAUTION
Prolinate Injection should be used with caution in patients with liver disease. Dose adjustment of Prolinate Injection may be needed. Please consult your doctor.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.
No substitutes found for this medicine

Quick tips

  • It makes you feel sleepy. Do not drive or do anything requiring mental focus until you know how it affects you. 
  • Inform your doctor if you are pregnant, planning pregnancy or breastfeeding.

Fact Box

Chemical Class
Phenothiazine Derivative
Habit Forming
No
Therapeutic Class
NEURO CNS
Action Class
Typical Antipsychotics

Interaction with drugs

Taking Prolinate with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Brand(s): Clowil, Odis, Kamestin
Life-threatening
Brand(s): Geoflu, Con F, Fucan
Life-threatening
Brand(s): Itraspan, Itoz, Sitra
Life-threatening
Brand(s): Ketozoe
Life-threatening

Patient concerns

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Prolinate injection is not avlaible can u tell me the subsutuite
Dr. Jyoti Kapoor Madan
Psychiatry
There are other antipsychotic drugs but these are not substitutes. For starting a new antipsychotic, a proper psychiatric evaluation is needed.
Patient has been taking Prolinate injection for several years and it suits her well - no side effects. We have prescription for Prolinate but it is not available. The website shows Monazine is a substitute injection with same composition. Can you prescribe it for Ms PATIENT based on the original prescription? My order is getting cancelled since Monazine is not on the original prescription. Thanks, anjana
Dr. Jyoti Kapoor Madan
Psychiatry
Medicines are prescribed after clinical examination. This portal is to guide you regarding your problems and clarify doubts. Please see a psychiatrist for treatment.
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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

  1. Stahl SM, editor. Fluphenazine. In: Stahl's Essential Pschopharmacology: Prescriber's Guide. 5th ed. New York, New York: Cambridge University Press; 2014. pp. 259-63.
  2. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 572-73.
  3. Drugs.com. Fluphenazine. [Accessed 25 Mar. 2019] (online) Available from:External Link
  4. Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006. Fluphenazine. [Updated 2018 Oct 31]. [Accessed 20 Feb. 2020] (online) Available from:External Link
  5. Central Drugs Standard Control Organisation (CDSCO). [Accessed 25 Mar. 2019] (online) Available from:External Link

Marketer details

Name: Sun Pharmaceutical Industries Ltd
Address: Plot no 107/108,Namli block , Ranipool, East Sikkim 737135
Country of origin: India

DISCONTINUED
We do not facilitate sale of this product at present

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