Take this medicine in the dose and duration as advised by your doctor. Wash and dry your vaginal area. Dip the tablet in lukewarm water just to moisten it. Lie on your back and gently insert the tablet into the vagina as high as possible with or without the use of an applicator as mentioned in the label. It is best to use it just before bedtime.
Dinoprostone will be inserted into an area high up in vagina. You may be asked to remain in lying down position for 20-30 minutes to keep the medication in place.
You may be monitored closely after administration of dinoprostone to check if the birth canal is opening, the contractions are not too strong, and to ensure the baby does not get distressed.
Special precautions need to be taken in women over 35 years, pregnancy of more than 40 weeks and women with pregnancy related complications.
Dinoprostone could cause an asthma attack. Inform your doctor if you are asthmatic and if you develop difficulty in breathing after the medication.
Inform your doctor if you have an eye problem (glaucoma), fits (epilepsy), diabetes, high blood pressure (hypertension) in the current or any previous pregnancies, Caesarean or any uterine surgery or if you have had abnormally strong contractions during previous labor or scarring of your womb from previous labor or are taking medicines for pain and/or inflammation (e.g. aspirin).
Dinoprostone will increase the effect of oxytocin which is used to increase the contractions of the womb. They should not be taken at the same time or close together.
PRIMIPROST 0.5MG Tablet VT may be unsafe to use during pregnancy.
Animal studies have shown adverse effects on the foetus, however, there are limited human studies. The benefits from use in pregnant women may be acceptable despite the risk. Please consult your doctor.
PRIMIPROST 0.5MG Tablet VT is probably unsafe to use during
Limited human data suggest that the drug could represent a significant risk to the baby.
PRIMIPROST 0.5MG Tablet VT does not usually affect your ability to drive.
PRIMIPROST 0.5MG Tablet VT should be used with caution in patients with kidney disease. Dose adjustment of PRIMIPROST 0.5MG Tablet VT may be needed. Please consult your doctor.
Use of PRIMIPROST 0.5MG Tablet VT is not recommended in patients with active kidney disease.
PRIMIPROST 0.5MG Tablet VT should be used with caution in patients with liver disease. Dose adjustment of PRIMIPROST 0.5MG Tablet VT may be needed. Please consult your doctor.
Use of PRIMIPROST 0.5MG Tablet VT is not recommended in patients with active liver disease.
Primiprost is a naturally occurring substance called prostaglandin. It softens and opens the part of the birth canal known as the cervix thereby inducting the labor (a process in which the womb (uterus) starts contracting).
Information last updated by Dr. Varun Gupta, MD Pharmacology on 1st Dec 2017.