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food interaction for POLYDAY

alcohol interaction for POLYDAY

pregnancy interaction for POLYDAY

lactation interaction for POLYDAY

There is no data available. Please consult doctor before consuming the drug.
Taking glimepiride with alcohol may affect blood glucose levels in patients with diabetes.
Taking metformin with alcohol may cause lactic acidosis and you may experience malaise, respiratory distress, slow or irregular heartbeat, somnolence, abdominal upset, or other unusual symptoms.
Taking Voglibose with alcohol reduce the blood sugar levels in diabetic patients.
Polyday 0.2mg/500mg/2mg tablet may be unsafe to use during pregnancy.
Either animal studies have shown adverse effect on fetus and there are no human studies or studies in human and animals are not available. It should be given only if potential benefits justifies risk to the fetus. Please consult your doctor.
Unknown. Human and animal studies are not available. Please consult your doctor.


Glimepiride(2 mg)


Glimepiride is used to lower the blood sugar levels in type 2 diabetes mellitus when diet, physical exercise and weight reduction alone are not adequate.

How it works

Glimepiride belongs to a blood sugar lowering group of medicines called sulfonylurea. Glimepiride increases the amount of insulin released by the pancreas, and thereby decreases the blood sugar level.

Common side effects

Nausea, Diarrhoea, Bruise, Bleeding, Blood in stool, Dark colored urine, Dizziness, Sore throat, Stomach pain / epigastric pain, Yellow discoloration of skin, Yellow discoloration of eye, Weakness, Fever
Metformin(500 mg)


Metformin is an antidiabetic medicine that helps to control blood sugar in people with type 2 diabetes mellitus.

How it works

Metformin belongs to class of medications called antidiabetics.It decreases the amount of glucose absorbed from the food and the amount ofglucose made by liver. Metformin also increases the body's response to insulin(a natural substance that controls the amount of glucose in the blood).

Common side effects

Flatulence, Muscle pain, Abdominal bloating, Chest pain, Skin rash, Flushing, Abdominal pain, Nail disorder, Diarrhoea, Headache, Indigestion, Bitter taste, Constipation, Allergic reaction, Heartburn
Voglibose(0.2 mg)


Voglibose is used to reduce high post meal glucose level in diabetes mellitus in patients who have been using other diabetic medications.

How it works

Voglibose belongs to the class of medications that lowers blood sugar called anti-hyperglycemics (alpha-glucosidase inhibitor). Voglibose delays the digestion and absorption of carbohydrate in the intestine by inhibiting intestinal enzyme (alpha glucosidase) which results in reduction of increase in blood glucose level after meal.

Common side effects

Numbness, Sweating, Rash, Abdominal pain, Abnormal blood cell count, Anemia, Blurred vision, Constipation, Diarrhoea, Flatulence, Hair loss, Heartburn, Hot flashes, Loss of appetite, Feeling of discomfort, Nausea, Facial swelling, Vomiting, Weakness


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Expert advice for POLYDAY

  • Take glimepiride just before or with the first main meal of the day.
  • Do not skip any meal while taking glimepiride.
  • Swallow the glimepiride tablet without crushing or chewing with at least half a glass of water.
  • Do not take glimepiride if you are allergic to  glimepiride, other sulfonylureas, sulfonamides
  • Glimepiride tablets should not be given to children and adolescents under 18 years of age.

Frequently asked questions for POLYDAY


 Q. Is glimepiride a generic drug?
Yes, glimepiride is a generic drug sold under several pharmaceutical brand names (Amaryl, Zoryl, etc.).
Q. Can I take glimepiride with metformin or insulin?
Glimepiride may be given in combination with metformin and/or insulin depending on your medical condition and as prescribed by the doctor.
Q. Does glimepiride cause fluctuations in weight,diarrhea, hair loss, erectile dysfunction, swelling, constipation?
Glimepiride is reported to cause low blood sugar level,weight gain, and swelling, but is not reported to cause diarrhea, constipation, hair loss, or erectile dysfunction.
Q. Is glimepiride a fast acting sulfa drug?
Glimepiride is a medium- to long-acting sulfonylurea drug against type 2 diabetes mellitus (action lasts for 24 hours). Its maximum effect is seen after 2-3 hours of drug intake.
Q. Is glimepiride same as glipizide, glyburide, metformin, or insulin?
They are not same. Glimepiride, glipizide and glyburide belong to the same class of drugs called sulfonylureas. Metformin belong to class called biguanides.Glimepiride causes release of insulin but it is not insulin.It should only be used if no other alternative drug is available. Please follow your doctor's advice regarding its use.


Q. Is Metformin a birth control pill/ insulin / statin/ banned drug?
Metformin (also available as glyciphage, glycomet, glycomet SR) is an antidiabetic drug used in treatment of type 2 diabetes mellitus, particularly in overweight patients, as an adjunct to the diet and exercise.
Q. Is metformin safe?
Metformin is generally safe if used at prescribed doses for the prescribed duration as advised by your doctor.
Q. Can I take metformin forever?
Metformin should be taken at prescribed doses for the prescribed duration as advised by your doctor.
Q. Is metformin good for weight loss / weight loss in non-diabetics?
Metformin is used for the treatment of type 2 diabetes mellitus, particularly in overweight patients. 


Q. Is voglibose/volixy approved by US FDA?
Voglibose is not approved by US FDA.

Q. Is voglibose better than acarbose?
No, voglibose and acarbose have similar overall effects but variation may exist depending on the individuals taking the drug. Always consult your doctor for an alternative drug of choice.

Q. Is voglibose safe?
Voglibose is safe if used at prescribed doses for the prescribed duration as advised by your doctor.


Content on this page was last updated on 20 April, 2014, by Dr. Varun Gupta (MD Pharmacology)