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MRP: Rs. 203.50 for 1 strip(s) (10 tablets each)
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Composition for PIRFENEX

Pirfenidone(200 mg)

food interaction for PIRFENEX

alcohol interaction for PIRFENEX

pregnancy interaction for PIRFENEX

lactation interaction for PIRFENEX

It is better to take Pirfenex 200 mg tablet with food.
Avoid Pirfenex 200 mg tablet with grapefruit juice.
Interaction with alcohol is unknown. Please consult your doctor.
Pirfenex 200 mg tablet may be unsafe to use during pregnancy.
Either animal studies have shown adverse effect on fetus and there are no human studies or studies in human and animals are not available. It should be given only if potential benefits justifies risk to the fetus. Please consult your doctor.
Unknown. Human and animal studies are not available. Please consult your doctor.


Pirfenidone(200 mg)


Pirfenex 200 mg tablet is used in the treatment of mild to moderate Idiopathic Pulmonary Fibrosis (IPF). IPF is chronic fibrotic and inflammatory lung disease where the lungs tissues become swollen and scarred over time due to synthesis and release of certain chemicals (pro-inflammatory cytokines such as tumor necrosis factor-alpha [TNF-?] and interleukin-1-beta [IL-1?]), causing difficulty in breathing.

How it works

Pirfenex 200 mg tablet is an anti-fibrotic and anti-inflammatory agent and belongs to a class of medications called pyridones. Pirfenex 200 mg tablet relieves conditions of idiopathic pulmonary fibrosis by reducing fibroblast growth (cells of the connective tissue which produce collagen and other fibres), reducing production of inflammatory chemicals and preventing accumulation of cell contents (extracellular matrix), thereby relieving swelling and inflammation of the lungs.

Common side effects

Vomiting, Nausea, Abdominal pain, Skin rash, Allergic reaction, Joint pain, Diarrhoea, Dizziness, Gastro-esophageal reflux disease, Headache, Indigestion, Insomnia, Sinus inflammation, Upper respiratory tract infection, Weight loss


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Expert advice for PIRFENEX

  • Pirfenidone makes you more sensitive to sunlight (photosensitivity). Avoid the sun (including sunlamps) whilst taking pirfenidone. Wear sunblock daily and cover your arms, legs and head to reduce exposure to sunlight.
  • Do not take pirfenidone if you are currently taking any other medicine such as tetracycline antibiotics, as they can make you more photo sensitive.
  • Do not take pirfenidone if you are currently taking any other medicine such as fluvoxamine, it should be discontinued prior to the initiation of pirfenidone therapy and avoided during pirfenidone therapy.
  • Avoid using pirfenidone if you are pregnant, breastfeeding or planning to get pregnant.
  • Avoid smoking or use tobacco products.
  • Stop smoking while on and before beginning pirfenidone, as it can reduce the effect of pirfenidone.
  • Pirfenidone may cause dizziness and tiredness. If you feel tired or dizzy be caution while driving or operating machinery.
  • Stop using pirfenidone and consult your doctor immediately if you experience a serious allergic (hypersensitivity) reaction characterized by swelling of the face, lips and/or tongue, difficulty breathing or wheezing; or skin reaction to sunlight or sunlamps such as blistering and/or marked peeling of the skin.
  • Avoid using pirfenidone if you feel ill and unwell and have yellowing of the eyes or skin, with or without dark urine, accompanied by itching of the skin; or if you get signs of an infection such as a sore throat, fever, mouth ulcers or flu-like symptoms.

Frequently asked questions for PIRFENEX


Q. Is pirfenidone approved by FDA?
Yes, pirfenidone is approved by the FDA for Idiopathic Pulmonary Fibrosis 
Q. Is pirfenidone a steroid?
No, pirfenidone is not a steroid.
Q. How much does pirfenidone cost?
The price of pirfenidone may vary depending upon the brand prescribed to you. Please read the instruction on the package for the correct price of the product.


Content on this page was last updated on 18 October, 2016, by Dr. Varun Gupta (MD Pharmacology)