Pioglit 15mg Tablet

icon
Sun Pharmaceutical Industries Ltd

Composition for Pioglit 15mg Tablet

iconPrescription Required

Primarily used for

Potentiallyunsafewith
icon
Alcohol
49
₹4.9/Tablet
10 tablets in 1 strip
ADD TO CART

Medicine Overview of Pioglit Tablet

uses

Uses of Pioglit Tablet

Pioglit 15mg Tablet is used in the treatment of type 2 diabetes.
uses

Side effects of Pioglit Tablet

Common

Blurred vision, Respiratory tract infection, Bone fracture, Numbness.

uses

How to use Pioglit Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. It can be taken with or without food, but it is better to take Pioglit 15mg Tablet at a fixed time.

How Pioglit Tablet works

Pioglit 15mg tablet is an anti-diabetic medicine. It works by increasing the body's sensitivity to insulin, a natural substance that helps control blood sugar levels.

In Depth Information on Pioglit Tablet

Expert advice for Pioglit Tablet

  • Highly effective in decreasing haemoglobin A1c level (Hemoglobin A1c measures average blood sugar over time).
  • Pioglit may rarely cause hypoglycemia.
  • Pioglit is more likely to cause weight gain as compared to other anti-diabetic medicines.
  • Pioglit may cause fluid retention (edema), ranging from mild ankle swelling to severe swelling in the lungs that make it hard to breathe.
  • Inform your doctor if you have ever been diagnosed with any heart problems (high blood pressure, heart attack, heart failure, slow or irregular heart rate).
  • Inform your doctor if you have ever been diagnosed with kidney or liver problems.
  • Inform your doctor if you have ever been diagnosed with bladder cancer.
video imgplay img
Warnings
Special precautions for Pioglit 15mg Tablet
icon
Alcohol
CAUTION
Taking pioglitazone with alcohol may affect blood glucose levels in patients with diabetes.
icon
Pregnancy
WEIGH RISKS VS BENEFITS
Pioglit 15mg Tablet may be unsafe to use during pregnancy.

Animal studies have shown adverse effects on the foetus, however, there are limited human studies. The benefits from use in pregnant women may be acceptable despite the risk. Please consult your doctor.
...
+more
icon
Lactation
Pioglit 15mg Tablet is probably safe to use during lactation. Limited human data suggests that the drug does not represent a significant risk to the baby.

Monitor the breastfed baby’s blood sugar during treatment with Pioglit 15mg Tablet
...
+more
icon
Driving
SAFE
Pioglit 15mg Tablet does not usually affect your ability to drive.
icon
Kidney
SAFE
Pioglit 15mg Tablet is safe to use in patients with kidney disease. No dose adjustment of Pioglit 15mg Tablet is recommended.

Use of Pioglit 15mg Tablet is not recommended in patients undergoing dialysis.
...
+more
icon
Liver
CAUTION
Pioglit 15mg Tablet should be used with caution in patients with liver disease. Dose adjustment of Pioglit 15mg Tablet may be needed. Please consult your doctor.

Use of Pioglit 15mg Tablet is not recommended in patients with severe liver disease.
...
+more
Severely interacts with other drugs like
Decmax 4mg Tablet, Derinide 0.5mg Respules 2ml, Apidra 100IU Cartridge 3ml, Decamycin 4mg Injection

Missed Dosageuses

If you miss a dose of Pioglitazone, skip it and continue with your normal schedule. Do not double the dose.

Patient Concerns

Frequently asked questions for Pioglit 15mg Tablet

Frequently asked questions for Pioglitazone

No. Pioglit is an anti-diabetic medication. Blood thinners are the medicine that prevents the formation of a harmful blood clot. These include medicines like Aspirin, Heparin and Warfarin.
Q. Is Pioglit a diuretic?
No. Pioglit is not a diuretic. It is used in the treatment of Diabetes Mellitus. Diuretics are those medicine which increases urination.
Q. Can Pioglit used in Hepatitis B infection?
Some studies have shown that Pioglit may be helpful in preventing Hepatitis B Virus-associated Hepatocellular Cancer (Liver Cancer). However, these findings are still very preliminary and clear role has not been established.
Pioglit has been shown to inhibit Liver Cancer (HCC) recurrence in overweight Hepatitis C Virus-infected diabetic patients. It also improved insulin resistance (a state where the body is resistant to the effects and functions of the insulin hormone) in them.
Q. Can Pioglit used along with Vitamin D?
Studies indicate that Vitamin-D combined with Pioglit may be more effective in improving Bone Mineral Density and Bone Metabolism than Vitamin-D or Pioglit alone in the treatment of Diabetes Mellitus patients with kidney dysfunction (Diabetic Nephropathy).
Q. Can Pioglit be used along with sitagliptin?
Combination therapy with Sitagliptin and Pioglit leads to a substantial and sustained improvement in glycemic (blood sugar) control compared to the treatment with Pioglit alone. This is useful for patients who cannot tolerate Metformin or Sulfonylureas.
Recent evidence suggests that Pioglit may be beneficial in Alzheimer's disease (AD), decreasing the cognitive decline early in the disease process. However, larger studies are now in progress to establish the same.
Q. Can Pioglit and repaglinide combined in diabetes treatment?
For patients who previously failed oral antidiabetic therapy, the combination of Repaglinide and Pioglit have acceptable safety, with greater reductions of glycemic parameters (blood sugar levels) than using either agent alone.
Large population studies indicate that Pioglit is associated with an increased risk of bladder cancer. The absence of an association of bladder cancer with the other drug of the same class, Rosiglitazone, suggests that the increased risk is drug specific and not a class effect.
Q. Are Pioglit and rosiglitazone same?
Pioglit & Rosiglitazone both belong to a class of antidiabetics called Thiazolidinediones. Rosiglitazone has been removed from the market because using this drug was associated with increased risk of cardiovascular events like heart attack and stroke. This is not seen with Pioglit.
Q. Can Pioglit be used along with glimepiride in diabetes?
Pioglit when added to Glimepiride in Patients with Diabetes Mellitus, has been found to significantly reduce plasma lipid levels and significant improvement in blood pressure control related to a reduction in the insulin resistance.
No. Pioglit is not a steroid. It is an anti-diabetic medication which belongs to the class of thiazolidinediones.
Pioglit is an anti-diabetes drug used along with a proper diet and exercise program to control high blood sugar in patients with type 2 diabetes. Pioglit acts as an insulin sensitizer and decreases the extent of insulin resistance in the body too.
Pioglit cardiovascular safety profile compares favourably with that of Rosiglitazone. Pioglit has been found to be associated with bladder tumours but causality assessment has not been proved yet.
Pioglit increases the permeability of fluid in tiny blood vessels called capillaries. This results in easier movement of fluids across the membrane and their consequent accumulation, resulting in oedema (puffiness). Also, Pioglit causes increased sodium and water reabsorption from the kidney that contributes to the oedema.
The mechanism behind the link between Pioglit use and bladder cancer is still unknown. Studies have suggested that use of Pioglit for more than one year results in increased risk of development of tumour of the urinary bladder.
Pioglit can cause fluid retention and edema. Consequently, there is a lot of fluid in the body (fluid overload). As a result, it may precipitate heart failure (which worsens with fluid overload in those at risk).
Studies in animals have concluded that Pioglit improves the elasticity of the aortic wall ( the aorta is a large blood vessel that arises from the heart and supplies oxygenated blood to the rest of the body). This may be a mechanism by which it protects against atherosclerosis, but more studies are needed to confirm this.
The addition of Pioglit reduces daily insulin dosages, but study findings have not been consistent. Improvement of lipid profiles has also been weak with this combination therapy. Long-term studies are needed before any conclusions can be reached. Combination therapy should be primarily used for patients who achieve an insufficient reduction in blood sugar with insulin alone.
Q. Which is not safe in heart failure, Pioglit or rosiglitazone?
Pioglit & Rosiglitazone both belong to a class of antidiabetics called Thiazolidinediones. Rosiglitazone has been removed from the market because using this drug was associated with increased risk of cardiovascular events like heart attack and stroke. Pioglit can cause heart failure too, but the risk is less that that with Rosiglitazone. Both the medicines should be avoided in heart failure.
Fortunately, there are many alternatives to Pioglit- Metformin, Acarbose, Sitagliptin, Exenatide, Insulin or combination therapies of these medicines can be used.
Findings indicate that Pioglit treatment is associated with a reduced dementia risk in Diabetes mellitus patients. Prospective studies are needed to evaluate a possible neuroprotective effect in these patients in an ageing population.
Pioglit may be of use in infertile patients with polycystic ovary syndrome (PCOS) who are resistant to conventional ovulation induction such as by drugs like Clomiphene, Dexamethasone, or Metformin.
The use of Pioglit for plaque psoriasis treatment is controversial. Some studies revealed no effect of Pioglit 30 mg daily neither on the clinical response of moderate-to-severe psoriasis whereas others demonstrate that it could be considered as an efficacious and safe agent for the treatment of plaque psoriasis.
In a research study in a small number of autistic children, daily treatment with 30 or 60 mg Pioglit for 3–4 months induced apparent clinical improvement. Pioglit should be considered for further testing of therapeutic potential in autistic patients but as of now, autism is not an approved indication for Pioglit use.
Pioglit, either alone or as add-on therapy to conventional treatments, could clinically benefit patients of major depression according to a study.
A recent study shows that although Pioglit causes a significant decrease in blood sugar, HbA1C and lipid levels, it is associated with weight gain, which would limit its utility. It has not been shown to cause weight loss.
Pioglit has also been used to treat non-alcoholic steatohepatitis (fatty liver), but this use is presently considered experimental.
Pioglit reduces recurrent stroke and major vascular events in stroke patients with insulin resistance, prediabetes, and diabetes mellitus. However, its use as a preventive therapy requires more research.
+more

User Submitted Feedback For Pioglit 15mg Tablet

One of the following vendor pharmacies will deliver Pioglit 15mg Tablet: Health Arx Technologies Private Limited, Amishi Consumer Technologies P Ltd, Organic India Private Limited, Delhi Cryogenic Products Pvt Ltd, First Step Digital Pvt Ltd, Gupta Homoeo Pharmacy Pvt Ltd, Organic Wellness Products Private Limited, RK Sons, Pills Tree Super Pharmacy, Melting Pot Concepts Pvt Ltd, Zywie Ventures Pvt Ltd, Lifecare Chemist (PAN India), SBL Pvt Ltd, Satyog Enterprises Pvt Ltd, Ghantakarn International, Aashirwad Agency, Airveda Technologies Pvt Ltd, Fit and Glow Healthcare Pvt Ltd, Keshav Homeo Home, Radicura Pharmaceuticals Pvt Ltd, Jiva Ayurvedic Pharmacy Ltd, Perfect Nutrition, Sharma Traders, Bright Lifecare Pvt Ltd, Delhi Vendor, Maximaa Systems Ltd, Swadeshi Ayurved, Sri Jain Pharmacy, Inlife Pharma Pvt Ltd, Herbolab India Pvt Ltd, Ayush Enterprises, Priya Entreprises, Gallop Trading Company, Planet Ayurveda, Life aid Homeopathic and ayurvedic store, Emmbros Overseas, Makvis, Herboveda India, Rusan Healthcare Pvt Ltd, Delhi Distributors, Hexagon Nutrition Pvt. Ltd., BestSource Nutrition Private Limited, Biomed Distributors, Star medicare, DF Pharmacy Ltd, Do You Even Gym, 9 to 9 Farmacia, The Medicine Mart, Bantom Laboratories P Ltd , 9to9 Farmacia (South), Madhu Medicos, M/s R&G Healthcare (Delhi)

Substitutes for Pioglit Tablet

Piosys 15mg Tablet
Systopic Laboratories Pvt Ltd
₹1.4/Tablet
save 71%
K Pio 15mg Tablet
Blue Cross Laboratories Ltd
₹1.6/Tablet
save 67%
₹1.73/Tablet
save 65%
G Tase 15mg Tablet
Unichem Laboratories Ltd
₹2.29/Tablet
save 53%
Pzone 15mg Tablet
Aretaeus Pharmaceuticals
₹2.83/Tablet
save 42%
Top Diabetologists
doctor
Dr. Sunil Sekhri
MBBS, Fellowship
4.1
doctor
Dr. Rajiva Gupta
MBBS, Diploma, MD
4.2
doctor
Dr. Sanjay Gupta
MBBS, MD, Diploma, DNB
4.0
doctor
Dr. Ambrish Mithal
MBBS, MD, DM
4.5
doctor
4.9
cross img