Author Details
Written By
BDS
Reviewed By
MBA, MD Pharmacology
Last updated
06 Dec 2023 | 05:39 PM (IST)

We provide you with authentic, trustworthy and relevant information

Want to know more

Have issue with the content?

Report Problem

Pexep Plus 12.5 Capsule IR

Prescription Required
Storage
Store below 30°C

Product introduction

Pexep Plus 12.5 Capsule IR is a prescription medicine used to treat depression. It is a combination medicine which works by increasing the level of chemical messengers in the brain that improves mood. It also calms the brain by decreasing the abnormal and excessive activity of the nerve cells.

Pexep Plus 12.5 Capsule IR can be taken with or without food. It is advised to take it at a fixed time each day to maintain a consistent level of medicine in the blood. Take this medicine in the dose and duration advised by your doctor as it has habit-forming potential. Try to never skip any doses, but if you miss a dose of this medicine, take it as soon as you remember. Finish the full course of treatment even if you feel better. It is important not to stop taking this medicine suddenly as it may result in withdrawal symptoms.

Some common side effects of this medicine include nausea, vomiting, confusion, memory impairment, low sexual desire, confusion, and delayed ejaculation. It may cause dizziness and sleepiness. So, do not drive or do anything that requires mental focus until you know how this medicine affects you.  It is important to inform your doctor if you develop any unusual changes in mood or depression as this medicine may cause suicidal thoughts.

Take caution while taking medicine if you are suffering from liver disease. Your doctor should also know about all other medicines you are taking as many of these may make this medicine less effective or change the way it works. Inform your doctor if you are pregnant, planning pregnancy or breastfeeding.

Uses of Pexep Plus Capsule ER

Benefits of Pexep Plus Capsule ER

In Depression

Pexep Plus 12.5 Capsule IR works by affecting the balance of certain chemicals (such as serotonin) in the brain. It helps improve mood and feelings of wellbeing, relieve anxiety and tension, helps you sleep better, and increase your energy level. It is an effective antidepressant but may cause drowsiness. You need to take it regularly as it is prescribed for it to be most effective and should not stop taking it suddenly.

Side effects of Pexep Plus Capsule ER

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Pexep Plus

  • Nausea
  • Vomiting
  • Diarrhea
  • Confusion
  • Memory impairment
  • Uncoordinated body movements
  • Drowsiness
  • Tiredness
  • Anorgasmia (decreased orgasm)
  • Low sexual desire
  • Delayed ejaculation

How to use Pexep Plus Capsule ER

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Pexep Plus 12.5 Capsule IR may be taken with or without food, but it is better to take it at a fixed time.

How Pexep Plus Capsule ER works

Pexep Plus 12.5 Capsule IR is a combination of two medicines:.

Safety advice

Alcohol
UNSAFE
It is unsafe to consume alcohol with Pexep Plus 12.5 Capsule IR.
Pregnancy
UNSAFE
Pexep Plus 12.5 Capsule IR is highly unsafe to use during pregnancy. Seek your doctor's advice as studies on pregnant women and animals have shown significant harmful effects to the developing baby.
Breast feeding
CONSULT YOUR DOCTOR
Pexep Plus 12.5 Capsule IR is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Driving
UNSAFE
Pexep Plus 12.5 Capsule IR may cause side effects which could affect your ability to drive.
Kidney
SAFE IF PRESCRIBED
Pexep Plus 12.5 Capsule IR is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Pexep Plus 12.5 Capsule IR may not be needed in these patients. Please consult your doctor.
Use of Pexep Plus 12.5 Capsule IR can cause excessive sleepiness in patients with end stage kidney disease.
Liver
CAUTION
Pexep Plus 12.5 Capsule IR should be used with caution in patients with liver disease. Dose adjustment of Pexep Plus 12.5 Capsule IR may be needed. Please consult your doctor.

What if you forget to take Pexep Plus Capsule ER?

If you miss a dose of Pexep Plus 12.5 Capsule IR, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.
No substitutes found for this medicine

Quick tips

  • Pexep Plus 12.5 Capsule IR is prescribed for the treatment of depression.
  • It is better to take it with a snack or just after eating breakfast, as this will help to reduce the likelihood of you feeling sick as a side-effect.
  • It can take a week or two after starting this treatment before the effect begins to build up, and 4-6 weeks before you feel the full benefit. Do not stop taking it after a week or two, feeling it is not helping.
  • Avoid taking antacids 2 hours before or after taking Pexep Plus 12.5 Capsule IR as they make it harder for your body to absorb the medicine.
  • Inform your doctor immediately if you get thoughts about harming yourself or ending your life.
  • If you have diabetes, you will be asked to monitor your blood glucose level regularly as this medicine may affect the levels of sugar in your blood.
  • Try to keep your regular appointments with your doctor. This is so your doctor can check on your progress.

Fact Box

Habit Forming
Yes
Therapeutic Class
NEURO CNS

Patient concerns

arrow
I am suffering from anxiety and consulting a psychiatrist,for the past 1 year I am having ,pexep CR 37.5 mg,my weight has got increased 20 kg in the last 1year .Is it safe to take pexep cr.how long will I have to take this medicine.
Dr. Jyoti Kapoor Madan
Psychiatry
If your weight gain is associated with use of pexep, you should discuss with your doctor. There are ways of controlling your weight. If that doesn't work, there are other anti depressants with low weight gain potential like desvenlafaxin or bupropion. SSRIs may need to continue for long periods and have been ft to be generally safe.
I have been taking pexep cr 25 for one year then reduced to 12.5 1 month and now taking half of 12.5 since last one month. This medicine has shown side effects such as weight gain by 15 kg and swelling in ankles. Withdrawal causes headache. Please suggest some brain relaxant which has minimum side effects.
Dr. Vikas Sharma
Neurology
U can try nexito 5 mg od Better to visit psychiatrist
arrow

User feedback


FAQs

Q. Are there any important warnings associated with the use of Pexep Plus 12.5 Capsule IR?

Pexep Plus 12.5 Capsule IR may increase the suicidal thoughts or actions in some patients, in the first few months of the treatment. Patients having mood or behavioral disorder have a high risk of suicidal thoughts and actions. You should pay close attention and report your doctor of any changes in behavior or mood. Make sure that you visit the doctor for the follow-up appointments as scheduled.

Q. Can I stop taking Pexep Plus 12.5 Capsule IR when my symptoms are relieved?

No, you should continue taking Pexep Plus 12.5 Capsule IR even if you feel well. If you stop Pexep Plus 12.5 Capsule IR suddenly, serious withdrawal symptoms may occur. Your doctor will probably decrease your dose gradually.

Q. How to manage weight gain associated with the use of Pexep Plus 12.5 Capsule IR?

There are reports that suggest that the use of Pexep Plus 12.5 Capsule IR can cause weight gain. If you keep good eating habits and exercise regularly, you might not gain any weight. It is important to remember that it is easier to stop weight gain than losing increased weight.

Q. Can the use of Pexep Plus 12.5 Capsule IR cause sleepiness?

Yes, Pexep Plus 12.5 Capsule IR can make you feel sleepy. Avoid driving, operating machinery, working at heights or participating in potentially dangerous activities till you know how this medicine affects you.

Q. Can the use of Pexep Plus 12.5 Capsule IR affect my sex life?

The use of Pexep Plus 12.5 Capsule IR can affect the sexual life of both men and women. Different sexual problems can occur due to Pexep Plus 12.5 Capsule IR like decreased sexual desire, erectile dysfunction (inability to develop or maintain erection during the sexual activity) and inability to reach orgasm. It can also cause a decrease in satisfaction and cause discomfort during intercourse. If you experience these problems, discuss with your doctor.

Q. Can I drink alcohol while taking Pexep Plus 12.5 Capsule IR?

No, do not drink alcohol while taking Pexep Plus 12.5 Capsule IR. Drinking alcohol can increase the severity of drowsiness or sleepiness caused by Pexep Plus 12.5 Capsule IR.

Q. How long does Pexep Plus 12.5 Capsule IR take to work?

Everybody responds differently to treatment. In general, it can take several weeks to feel the full benefits of Pexep Plus 12.5 Capsule IR, although some people may start to feel better sooner. When taking Pexep Plus 12.5 Capsule IR, it is important to give it time to work.

Q. What are the instructions for the storage and disposal of Pexep Plus 12.5 Capsule IR?

Keep this medicine in the packet or the container it came in, tightly closed. Store it according to the instructions mentioned on the pack or label. Dispose of the unused medicine. Make sure it is not consumed by pets, children and other people.

Related ayurvedic ingredients

Want to share the information?

Disclaimer:

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

  1. Paroxetine. Miami, Florida:Noven Therapeutics; 2003 [revised 06-2013]. [Accessed 23 Apr. 2019] (online) Available from:External Link
  2. Clonazepam. Boucherville, Québec: Sandoz Canada Inc.; 2018. [Accessed 23 Apr. 2019] (online) Available from:External Link
  3. Paroxetine. South Ruislip, Middlesex: Aurobindo Pharma - Milpharm Ltd.; 2008 [revised 25 Nov. 2018]. [Accessed 23 Apr. 2019] (online) Available from:External Link
  4. Clonazepam. Boucherville, Québec: Sandoz Canada Inc.; 2018. [Accessed 23 Apr. 2019] (online) Available from:External Link

Marketer details

Name: Intas Pharmaceuticals Ltd
Address: Chinubhai Centre, Off. Nehru Bridge, Ashram Road, Ahmedabad - 380009. Gujarat. India.
Country of origin: India

NOT FOR SALE
We do not facilitate sale of this product at present

INDIA’S LARGEST HEALTHCARE PLATFORM

260m+
Visitors
31m+
Orders Delivered
1800+
Cities
Get the link to download App
Reliable

All products displayed on Tata 1mg are procured from verified and licensed pharmacies. All labs listed on the platform are accredited

Secure

Tata 1mg uses Secure Sockets Layer (SSL) 128-bit encryption and is Payment Card Industry Data Security Standard (PCI DSS) compliant

Affordable

Find affordable medicine substitutes, save up to 50% on health products, up to 80% off on lab tests and free doctor consultations.

LegitScript approved
India's only LegitScript and ISO/ IEC 27001 certified online healthcare platform

Know more about Tata 1mgdownArrow

Access medical and health information

Tata 1mg provides you with medical information which is curated, written and verified by experts, accurate and trustworthy. Our experts create high-quality content about medicines, diseases, lab investigations, Over-The-Counter (OTC) health products, Ayurvedic herbs/ingredients, and alternative remedies.

Order medicines online

Get free medicine home delivery in over 1800 cities across India. You can also order Ayurvedic, Homeopathic and other Over-The-Counter (OTC) health products. Your safety is our top priority. All products displayed on Tata 1mg are procured from verified and licensed pharmacies.

Book lab tests

Book any lab tests and preventive health packages from certified labs and get tested from the comfort of your home. Enjoy free home sample collection, view reports online and consult a doctor online for free.

Consult a doctor online

Got a health query? Consult doctors online from the comfort of your home for free. Chat privately with our registered medical specialists to connect directly with verified doctors. Your privacy is guaranteed.