1mg, best e pharmacy in India


MRP: Rs. 6.46 for 1 strip(s) (10 tablets each)
Unfortunately, we don't have any more items in stock

food interaction for PEPDAC D

alcohol interaction for PEPDAC D

pregnancy interaction for PEPDAC D

lactation interaction for PEPDAC D

There is no data available. Please consult doctor before consuming the drug.
Interaction with alcohol is unknown. Please consult your doctor.
Pepdac d 10mg/10mg/20mg tablet may be unsafe to use during pregnancy.
Either animal studies have shown adverse effect on fetus and there are no human studies or studies in human and animals are not available. It should be given only if potential benefits justifies risk to the fetus. Please consult your doctor.
Unknown. Human and animal studies are not available. Please consult your doctor.


Domperidone(10 mg)


Domperidone is used to treat vomiting or nausea caused due to indigestion, diseases or drugs. It is also used to relieve fullness of stomach, belching and heavy bloating, gas and heartburn for a longer period up to 2 weeks.

How it works

Domperidone belongs to a class of medicines known as anti-emetics. Domperidone acts by helping food move faster through the food pipe, stomach and gut; thus normalising the digestion process.

Common side effects

Abnormal heart rhythm, Breast tenderness, Breast pain, Diarrhoea, Drowsiness, Dry mouth, Headache, Irritation, Loss of libido
Ranitidine(10 mg)


Ranitidine is used to treat and prevent ulcers in the stomach and intestine. It also treats diseases in which the stomach produces too much acid, such as Zollinger-Ellison syndrome. Ranitidine is also used to treat gastroesophageal reflux disease (GERD) and other conditions in which acid backs up from the stomach into the esophagus, causing heartburn.

How it works

Ranitidine belongs to a class of drugs called H2 receptor antagonists. It acts by blocking the action of chemical called histamine on proteins called H2 receptors in the stomach and intestine which are involved in producing acid thereby decreasing acid formation.

Common side effects

Nausea, Liver enzyme increased, Abdominal pain, Allergic reaction, Bronchoconstriction (constriction of air passages), Chest pain, Constipation, Diarrhoea, Dizziness, Headache, Increased creatinine level in blood, Sudden decrease in blood pressure
Simethicone(20 mg)


Simethicone is used to relieve painful pressure, hiccups, bloating and fullness caused by excess gas in the stomach and intestines in adults as well as in children.

How it works

Simethicone belongs to class of medications called surface active substances. It is an antifoaming agents and works by acting on inner lining of intestine and allowing gas bubbles to come together more easily helping to release trapped wind.

Common side effects

Allergic reaction


2 Substitutes
Sorted By

Expert advice for PEPDAC D

  • Do not take Domperidone, if you are allergic to it or to any other content in the tablets.
  • Do not take the medicine, if you notice black, tarry stools (bowel motions) or blood in your stools, blockage or tear in the intestines or if you have a tumor of the pituitary gland (prolactinoma).
  • Do not take the drug, if you have moderate to severe liver disease, heart problems (irregular heart rate or heart failure) or abnormal salt levels in the blood.
  • Do not crush or chew the tablets, swallow them whole with a glass of water.
  • Do not take the drug if you intend to drive or operate heavy machinery as it may cause drowsiness.
  • Always take the tablets 15 to 30 minutes before meals and, if needed, before going to bed at night.
  • Consult your doctor, if you are above 60 years of age and taking domperidone for a long period of time.
  • Inform your doctor, if you are already taking medicines for fungal infections (ketoconazole) or antibiotics (e.g. gentamycin, erythromycin).

Frequently asked questions for PEPDAC D


Q. What is Domperidone/ domstal used for and how long can I take it?
Domperidone (also known as domstal) is used for the treatment of short-term (upto 48 hours) and long-term (upto 2 weeks) problems of nausea, vomiting, belching, gas, heartburn and bloating (not to be confused as laxative, steroid or antacid). Always take the drug exactly as your doctor has told you to.
 Q. Is domperidone an over the counter drug?
No, domperidone is not an OTC drug and it is not advisable to take it without a prescription.
Q. Can I take domperidone with citalopram?
Domperidone may increase the sedative effect of citalopram and may interact with other drugs like antibiotics, pain-killers or anti-fungals. Consult your doctor if you are taking any of these medicines.
Q. Does domperidone cause weight-gain?
No. Domperidone does not cause weight-gain. If you notice an abnormal weight-gain, visit your doctor.
 Q. Does domperidone raise the blood pressure or cause depression?
These effects are generally not seen with use of domperidone. But if you are experiencing these side effects, please consult your doctor.


Q. Is ranitidine safe?
Yes. Ranitidine (also available as rantac/ aciloc 150/ aciloc 300/ zantac) is safe if used at prescribed doses for the prescribed duration as advised by your doctor.
Q. Is ranitidine/rantac an antacid?
No. Ranitidine does not neutralize stomach acids.
Q. Is ranitidine a PPI?
No. Ranitidine reduces acid production in the stomach and intestine by blocking H2 receptors and has no known inhibitory effect proton pumps. It is a H2 receptor antagonist, and not a proton pump inhibitor (PPI).
Q. Is ranitidine the same as omeprazole?
No. Ranitidine and omeprazole are two different drugs with similar uses but different mechanism of action. Ranitidine reduces acid production in the stomach and intestine by blocking H2 receptors; whereas, omeprazole blocks proton pumps to curb acid production.
Q. Is ranitidine better than omeprazole?
Ranitidine and omeprazole are two different drugs with similar uses but different mechanism of action and so cannot be compared.
Q. Is ranitidine over the counter?
No. Ranitidine is not an over the counter (OTC) drug. It belongs to a class of prescription drugs.
Q. What is Rantac-D plus?
Rantac-D plus is a trade name for combination of active drugs ranitidine, omeprazole and domperidone. It is used to prevent excess acid production in the stomach and small intestine and to treat vomiting or urge to vomit (nausea) caused due to indigestion, diseases or drugs.
Q. Is ranitidine gluten free?
Yes. Ranitidine is a synthetic drug and free from any protein source that can contain gluten. Please refer to package insert of the prescribed brand before use.


Q. Is simethicone antacid?
No. Simethicone is not an antacid. But it is used in preparations which are used as antacid.

Q. Does it contain aspirin?
It does not contain aspirin.
Q. Is simethicone available over the counter?
Yes. Simethicone is sold over the counter without a prescription.
Q. Is simethicone gluten free?
Yes. Simethicone is gluten free. However, please refer to package insert of the prescribed brand before use.
Q. Is simethicone safe?
Yes. Simethicone is relatively safe.

Q. Is it safe for babies?
 Safe for infants and babies, if used as recommended. In case of any side-effects, consult your doctor.
Q. Is it safe to take simethicone daily?
It is advisable to take simethicone only as per the instructions of the doctor.
Q. Is simethicone good for gas?
Yes. Simethicone is effective in the treatment of gas.

Q. Does it have any side effects?
 It does not have any known serious side-effects.
Q. Can I take simethicone with ibuprofen, famotidine, lansoprazole, omeprazole, antibiotics, ranitidine, ciprofloxacin, Pepto-bismol, or Depakote?
Yes. Simethicone can be taken with ibuprofen, famotidine, lansoprazole, omeprazole, antibiotics, ranitidine, ciprofloxacin, Pepto-bismol (bismuth subsalicylate) or Depakote (divalproate sodium), if prescribed by your doctor.
Q. Does simethicone cause nausea or constipation?
Simethicone is not known to cause nausea or constipation. If you experience any such symptoms, please consult your doctor.
Q. Is simethicone effective against acid reflux?
Simethicone is effective in controlling acid reflux if combined with an antacid.


Content on this page was last updated on 10 October, 2014, by Dr. Varun Gupta (MD Pharmacology)