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MRP: Rs. 60.90 for 1 packet(s) (1 GM sachet each)
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Composition for PENTASA


food interaction for PENTASA

alcohol interaction for PENTASA

pregnancy interaction for PENTASA

lactation interaction for PENTASA

It is better to take Pentasa 1gm sachet with food.
Interaction with alcohol is unknown. Please consult your doctor.
Pentasa 1gm sachet may be unsafe to use during pregnancy.
Either animal studies have shown adverse effect on fetus and there are no human studies or studies in human and animals are not available. It should be given only if potential benefits justifies risk to the fetus. Please consult your doctor.
Unknown. Human and animal studies are not available. Please consult your doctor.




Pentasa 1gm sachet (also known as mesalamine) is used for the treatment and prevention of short episodes of ulcerative colitis (inflammatory disease of colon) and Crohn’s ileocolitis (inflammation of lining of ileum and colon).

How it works

Pentasa 1gm sachet belongs to a class of drugs called as amino salicylate drugs. It acts locally in the intestine to reduce the inflammation and prevents further swelling, ulcers or abscess (puss filled swelling).

Common side effects

Vomiting, Nausea, Liver enzyme increased, Acne, Allergic reaction, Itching, Back pain, Chest pain, Constipation, Dizziness, Dry mouth, Shortness of breath, Flatulence, Hair loss, Heartburn, Loss of appetite, Muscle pain, Joint pain


No substitutes found

Expert advice for PENTASA

  • Do not take the medicine if you are allergic to mesalazine, to any other content in the medicine, aspirin and other salicylate drugs.
  • Do not take mesalazine if you have severe kidney or liver problems, blood disorders or uncontrolled bleeding.
  • Do not take mesalazine if you have stomach or bowel ulcers or a history of bleeding ulcers, glucose-galactose mala absorption, Lapp-lactase deficiency or galactose intolerance.
  • Doctor’s advice should be considered in case of patients with liver, kidney or lung disease (asthma).
  • Avoid taking mesalazine if you are pregnant or planning to become pregnant or breast-feeding.

Frequently asked questions for PENTASA


Q. Is mesalazine a steroid, NSAID, immunosuppressant, blood-thinner or sulfa drug?
Mesalazine is not a steroid, NSAID, immunosuppressant, blood-thinner or sulfa drug. It is an anti-inflammatory drug.
Q. Can I take mesalazine forever?
No. Mesalazine should only be taken for the duration prescribed by your doctor.
Q. Is mesalazine safe?
Yes. Mesalazine is relatively safe if used as recommended. In case of any side-effects, consult your doctor.
Q. Can I take Asacol with Advil, Nyquil, tylenol, aspirin, Gaviscon, Imodium?
Asacol (mesalazine) can be taken with Nyquil, Tylenol (paracetamol), Gaviscon (sodium alginate) and Imodium (loperamide) only if prescribed by your doctor. It should not be taken with Advil (ibuprofen) or aspirin.
Q. Does mesalazine cause bleeding, weight gain, hair loss, immune suppression or liver problems?
Mesalazine may cause liver problems, immune suppression, hair loss, or bleeding. If you experience any such symptoms, please consult your doctor.
Q. Does mesalazine affect fertility or sperm count?
There is no evidence of mesalazine affecting fertility, but it may very rarely and reversibly reduce sperm count. If you experience any such problems, please consult your doctor.


Content on this page was last updated on 15 January, 2014, by Dr. Varun Gupta (MD Pharmacology)