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27 Oct 2020 | 04:48 PM (IST)
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Pegadria 50mg Injection

Prescription Required
Storage
Store in a refrigerator (2 - 8°C). Do not freeze.

Introduction

Pegadria 50mg Injection is used in the treatment of some kinds of cancer. It is also used in the treatment of breast cancer, where there is an increased cardiac risk. It can be used on its own, or sometimes given together with certain other medicines as part of combination chemotherapy.

Pegadria 50mg Injection can be used in both adults and children. It is given as injection into vein with extreme caution by a qualified medical professional. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to. It makes contraceptive pills less effective, so it advised to use reliable contraception during and after 6 months of the treatment.

The most common side effects of this medicine include nausea, vomiting, rash, weakness, low blood platelets. If they do not go away or get worse, tell your doctor. There may be ways of preventing or reducing these effects. It is very strong medicine and some people may develop serious side effects while taking it. This medicine may lead to problems with your blood, liver or heart. Your doctor will advise you regular blood tests to check for these.

Before taking this medicine, let your doctor know if you have liver disease. Your doctor should also know about all other medicines you are taking as many of these may make this medicine less effective or change the way it works. Tell your doctor if you are pregnant or breastfeeding.

Uses of Pegadria Injection

Benefits of Pegadria Injection

In Cancer

Pegadria 50mg Injection helps to treat certain kinds of cancer. It may be used alone or in combination with other medicines to treat cancer in various parts of the body. It relieves the symptoms of breast cancer such as breast lumps, bloody discharge from nipples or changes in the shape or texture of the breast. Pegadria 50mg Injection kills or stops the growth of cancer cells and also prevents the multiplication of cancer cells. It is a potent and very toxic medicine and you should discuss the risks and benefits with your doctor. You should avoid drinking alcohol while having this treatment and drink plenty of water to stay hydrated.

Side effects of Pegadria Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Pegadria

  • Nausea
  • Vomiting
  • Rash
  • Weakness
  • Low blood platelets
  • Fatigue
  • Fever
  • Decreased white blood cell count (neutrophils)
  • Loss of appetite
  • Anemia (low number of red blood cells)
  • Constipation
  • Stomatitis (Inflammation of the mouth)
  • Diarrhea
  • Painful blisters on hands and feet

How to use Pegadria Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Pegadria Injection works

Pegadria 50mg Injection is an anti-cancer medication. It works by damaging the genetic material (DNA) of the cancer cells and stops their growth and multiplication.

Safety Advice

Alcohol
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Pegadria 50mg Injection. Please consult your doctor.
Pregnancy
CONSULT YOUR DOCTOR
Pegadria 50mg Injection is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
Breastfeeding
CONSULT YOUR DOCTOR
Information regarding the use of Pegadria 50mg Injection during breastfeeding is not available. Please consult your doctor.
Driving
UNSAFE
Pegadria 50mg Injection may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Kidney
SAFE IF PRESCRIBED
Pegadria 50mg Injection is safe to use in patients with kidney disease. No dose adjustment of Pegadria 50mg Injection is recommended.
Caution is advised in patients with severe kidney disease as the information available is limited for use of this medicine in these patients.
Liver
CAUTION
Pegadria 50mg Injection should be used with caution in patients with liver disease. Dose adjustment of Pegadria 50mg Injection may be needed. Please consult your doctor.
Use of Pegadria 50mg Injection is not recommended in patients with severe liver disease.

Alternate Brands

For informational purposes only. Consult a doctor before taking any medicines.
Pegadria 50mg Injection
₹313.1/ml of Injection
₹32.56/ml of Injection
save 90%
₹480/ml of Injection
53% costlier
Lippod 50mg Injection
Celon Laboratories Ltd
₹728/ml of Injection
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Lipisol 50mg Injection
Alkem Laboratories Ltd
₹816.33/ml of Injection
161% costlier
Doxopar 50mg Injection
Parenteral Drugs India Ltd
₹1200/Injection
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Quick Tips

  • Pegadria 50mg Injection helps treat cancer of the breast, blood, and ovaries.
  • It is given through a drip into a vein (intravenous infusion) by a doctor or nurse.
  • It may make you feel tired or sleepy.  Do not drive or do anything that requires mental focus until you know how it affects you.
  • Use a reliable contraceptive method to prevent pregnancy while you are taking this medicine and for 6 months after stopping treatment.
  • Inform your doctor if you notice sores, discolouration or any discomfort in your mouth.
  • Your doctor may get regular blood tests done to monitor your blood cells, liver, and heart function during treatment with this medicine.
  • Inform your doctor immediately if you notice any signs of infection such as fever, sore throat or rash.

Fact Box

Chemical Class
Anthracycline Derivative
Habit Forming
No
Therapeutic Class
ANTI NEOPLASTICS

Patient Concerns

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My child having JIA, i use Folitrax 50mg injection every week . How to recover
Vipul Aggarwal
Pl consult a rheumatologist for same
He has prostate cancer patient under gone surgery and biopsy report confirm it. He was taking lupride injection quarterly. but this injection is not available now. his PSA is now 14.3. .please suggest us.
Dr. Vijay Sharnangat
Medical Oncology and Hematology
Will forward you number, you will get it from himcall him for Injection
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User Feedback


FAQs

Q. How does doxorubicin work?

Doxorubicin is anti-cancer or antineoplastic chemotherapy drug that belongs to a class of medication called anthracyclines. It slows down or stops the growth of cancer cells by interfering with DNA of the cancer cell

Q. Is doxorubicin liposomal a vesicant?

Doxorubicin liposomal is not a vesicant

Q. What is liposomal doxorubicin?

The molecules of doxorubicin are coated in a fatty capsule called as liposome. This liposome protects the body and allows the doxorubicin to remain in the blood circulation for a longer duration. This means that more amount of drug can be delivered to the cancer cells with less side effects.

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Disclaimer:

1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover all possible side effects, drug interactions or warnings or alerts. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

  1. Chabner BA, Bertino J, Cleary J, et al. Cytotoxic Agents. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 1714-15.
  2. Chu E, Sartorelli AC. Cancer Chemotherapy. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 952.
  3. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 431-33.
  4. Doxorubicin hydrochloride liposome. Bedford, Ohio: Ben Venue Laboratories, Inc.; 1995 [revised May 2007]. (online) Available from:External Link
  5. Doxorubicin hydrochloride. Beerse, Belgium: Janssen-Cilag International NV; 21 Jun. 1996 [revised 22 May 2018]. [Accessed 27 Mar. 2019]. (online) Available from:External Link
  6. Drugs.com. Doxorubicin Pregnancy and Breastfeeding Warnings. [Accessed 27 Mar. 2019]. (online) Available from:External Link
  7. Central Drugs Standard Control Organisation (CDSCO). [Accessed 27 Mar. 2019] (online) Available from:External Link

Manufacturer/Marketer Address

Chinubhai Centre, Off. Nehru Bridge, Ashram Road, Ahmedabad - 380009. Gujarat. India.
Best Price
₹6653.39
MRP7827.52  Get 15% OFF
Inclusive of all taxes
25 ml in 1 vial
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