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Pari CR 37.5 Tablet

Prescription Required
SALT COMPOSITION
Storage
Store at room temperature (10-30°C)
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Overview

Introduction

Pari CR 37.5 Tablet is a type of antidepressant belonging to the selective serotonin reuptake inhibitor (SSRI) group of medicines. It is widely prescribed to treat depression and anxiety-related conditions like panic disorder, obsessive-compulsive disorder, and post-traumatic stress disorder (PTSD).

Pari CR 37.5 Tablet helps many people to recover from depression by improving their mood and relieving anxiety and tension. It can be taken with or without food. The dose and how often you need it will be decided by your doctor so that you get the right amount to control your symptoms.

Your doctor may start you on a lower dose and increase it gradually. Do not change the dose or stop taking it without talking to your doctor, even if you feel well. Doing so may make your condition worse or you may suffer from unpleasant withdrawal symptoms (anxiety, restlessness, palpitations, dizziness, sleep disturbances, etc).

To get the most benefit, take this medicine regularly at the same time each day. Your doctor may advise you to take it in the morning if you have trouble sleeping. It may take a few weeks before you start feeling better. Let your doctor know if you do not see any improvement even after 4 weeks.

Some common side effects of Pari CR 37.5 Tablet include nausea, fatigue, dry mouth, loss of appetite, increased sweating, dizziness, nervousness, tremors, insomnia (difficulty in sleeping), and constipation. Sexual side effects like decreased sexual drive, delayed ejaculation, and erectile dysfunction may also be seen. Let your doctor know straight away if you develop any sudden worsening of mood or any thoughts about harming yourself.

Before taking this medicine, you should tell your doctor if you have epilepsy (seizure disorder or fits), diabetes, liver or kidney disease, heart problems, or glaucoma. These may affect your treatment. Pregnant or breastfeeding women should also consult their doctor before taking it. Some other medicines may affect the way it works, especially other antidepressants and medicines called MAO inhibitors. Please tell your doctor about all the medicines you are taking to make sure you are safe.

Uses of Pari Tablet PR

Benefits of Pari Tablet PR

In Depression

Pari CR 37.5 Tablet works by increasing the level of a chemical called serotonin in the brain. This improves your mood, relieves anxiety, tension, and helps you sleep better. It has fewer side effects than older antidepressants. It usually takes 4-6 weeks for this medicine to work so you need to keep taking it even if you feel it is not working. Do not stop taking it, even if you feel better unless your doctor advises you to.

In Panic disorder

Pari CR 37.5 Tablet can help relieve symptoms of many panic disorders including panic attacks. It can help you feel calmer and improve your ability to deal with problems. Do not stop taking it, even when you feel better, unless your doctor advises you to.

In Anxiety disorder

Pari CR 37.5 Tablet helps relieve symptoms of many anxiety disorders including obsessive-compulsive disorder and generalized anxiety disorder by increasing the level of a chemical called serotonin in your brain. It has fewer side effects than older antidepressants and is normally taken once a day. It helps you feel calm with a better ability to deal with problems. Exercise and a healthy diet can also improve your mood. Keep taking the medicine until your doctor advises you to stop.

Side effects of Pari Tablet PR

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Pari

  • Delayed ejaculation
  • Low sexual desire
  • Nausea
  • Tremor
  • Confusion
  • Dizziness
  • Dryness in mouth
  • Erectile dysfunction
  • Fatigue
  • Increased sweating
  • Insomnia (difficulty in sleeping)
  • Loss of appetite
  • Nervousness
  • Sleepiness

How to cope with side effects?

The occurrence of side effects varies from person to person. The following are a few ways of dealing with some of the common side effects. However, consult your doctor if these persist.

  • Coping with Delayed ejaculation and Erectile dysfunction
    Speak to your doctor as they may be able to change your medicine or offer other treatments that might help with the problem. Making healthy lifestyle changes and eating a healthy balanced diet can help. Lose weight if you are overweight. Exercise daily and try to reduce stress and anxiety. Avoid the use of alcohol, cigarettes or recreational drugs such as marijuana which can also affect sexual function. Counselling or psychotherapy can also be helpful.
  • Coping with Nausea
    You can help yourself by eating small, frequent meals rather than large ones and drinking plenty of fluids. Eat slowly. Avoid fatty, fried, spicy and very sweet foods. Eat cold or slightly warm food if the smell of cooked or cooking food makes you feel sick. Get plenty of fresh air. You could also try chewing ginger or drinking ginger tea. Eat bananas to replace potassium in your blood which can drop if you are sick (vomit). Use oral rehydration salts to replace vitamins and minerals lost through being sick. There are some medicines that can help you stop from feeling sick. Speak to your doctor if your condition does not improve.
  • Coping with Tremor
    These symptoms can be a sign that the dose is too high for you. It may help to change your dose or take your medicine at a different time of the day. There are also exercises that can improve muscle strength, control and coordination. In terms of lifestyle, avoid caffeine (in coffee, tea and chocolate), alcohol, and ask your doctor about other techniques to help you relax and manage stress. Talk to your doctor if this bothers you. Your doctor may be able to prescribe you medicines that can help.
  • Coping with Confusion
    If this medicine makes you feel this way, stop what you are doing and sit or lie down until you feel better. If the feeling does not go away or troubles you, do not take any more medicine and speak to a pharmacist or your doctor.
  • Coping with Dizziness
    This is usually short-lived and should go away within a few days. If this happens, stop what you are doing and sit or lie down until you feel better. Lying still in a dark, quiet room may help reduce the spinning feeling. Sleep with your head slightly raised on two or more pillows. Get up slowly from a lying or sitting position. Get plenty of rest and try to relax as being anxious can make it worse. Try taking this medicine at bedtime to reduce the symptoms. Drinking plenty of water and ginger tea may also help. Avoid alcohol, caffeine and smoking as it will make you feel worse. Avoid driving or using tools or machinery until you feel better.
  • Coping with Dryness in mouth
    Keep a drink available that you can sip through the day. Rinse your mouth with warm salted water and chew sugarless gum or hard candy. Try breathing through your nose more often than your mouth. Avoid caffeinated beverages, smoking and alcohol because they can make your condition worse. Use lip balm if your lips are also dry. Try to avoid foods that are acidic (like lemons), spicy, salty or sugary. If this side effect bothers you or does not go away, talk to your doctor about artificial saliva products or other suitable treatments.
  • Coping with Fatigue
    Make sure you rest and drink plenty of fluids. Eat a well-balanced diet to keep your energy levels up. Do not drink too much alcohol. Do not drive or use tools or machinery until you feel better. Other things that can help include doing some gentle exercise every day, prioritizing and pacing your activities and having a short nap if you need to. If you are still having problems after a week, speak to your doctor, as they may want to change you to a different type of medicine.
  • Coping with Increased sweating
    Try wearing loose, light-weighted, and breathable clothing. Use a strong antiperspirant and keep yourself cool with a fan. Changing your shoes and socks often might also help. Try cutting down on coffee, tea, and alcohol as they can increase your body temperature and promote sweating. Avoid spicy foods, this will help you deal with excessive sweating. If this does not help, talk to your doctor about other possible medications.
  • Coping with Loss of appetite
    It is important to eat, even if you do not feel like it. You might try switching to smaller meals and frequent snacks. Try eating healthy and nutritious snacks that are high in calories and protein, such as dried fruit and nuts. It is important to drink even if you cannot eat. But, do not fill your stomach with liquid before eating. Eat when you are most hungry. Exercise such as a short walk may also increase your appetite. Talk to your doctor about possible medication or supplements if your condition does not improve.
  • Coping with Nervousness
    This often disappears when the condition you are being treated for is managed. You could ask your doctor about changing the dose of your medicine or alternatives if it is affecting your daily life or causing you distress. Psychological treatments may be available. Some things you can do to help yourself include stopping smoking, cutting down the amount of alcohol and caffeine you drink, and doing regular exercise. You should also eat a healthy diet and find out how to get sleep if you are having trouble. Try talking to a friend or family member. Calming breathing exercises and other relaxation techniques may also help.
  • Coping with Sleepiness
    If the medicine is making you drowsy during the day, stop what you are doing and sit or lie down until you feel better. You can also consider taking a nap. Physical exercises such as walking may be helpful. Do not drink alcohol, as it will make you feel more tired. Avoid driving or operating heavy equipment when you are feeling drowsy. This problem usually goes away as your body gets used to the medicine. However, if it does not, ask your doctor if you can take your medicine at bedtime or whether the dose can be reduced.

How to use Pari Tablet PR

Use it as advised by your doctor or check the label for directions before use. Pari CR 37.5 Tablet may be taken with or without food, but it is better to take it at a fixed time.

How Pari Tablet PR works

Pari CR 37.5 Tablet is a selective serotonin reuptake inhibitor (SSRI) antidepressant. It works by increasing the levels of serotonin, a chemical messenger in the brain. This improves mood and physical symptoms of depression and also relieves symptoms of post traumatic stress disorder, panic disorder, anxiety and obsessive-compulsive disorder.

Safety Advice

Alcohol
UNSAFE
It is unsafe to consume alcohol with Pari CR 37.5 Tablet.
Pregnancy
UNSAFE
Pari CR 37.5 Tablet is highly unsafe to use during pregnancy. Seek your doctor's advice as studies on pregnant women and animals have shown significant harmful effects to the developing baby.
Breastfeeding
CONSULT YOUR DOCTOR
Pari CR 37.5 Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Driving
UNSAFE
Pari CR 37.5 Tablet may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Kidney
CAUTION
Pari CR 37.5 Tablet should be used with caution in patients with kidney disease. Dose adjustment of Pari CR 37.5 Tablet may be needed. Please consult your doctor.
Liver
CAUTION
Pari CR 37.5 Tablet should be used with caution in patients with liver disease. Dose adjustment of Pari CR 37.5 Tablet may be needed. Please consult your doctor.

Alternate Brands

For informational purposes only. Consult a doctor before taking any medicines.
Pari CR 37.5 Tablet
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Quick Tips

  • It can take 2-3 weeks for Pari CR 37.5 Tablet to start working.
  • Do not stop treatment suddenly as this may cause upset stomach, flu-like withdrawal symptoms and sleep disturbance.
  • If your doctor asks you to stop Pari CR 37.5 Tablet, you should reduce the dose slowly over 4 weeks.
  • Avoid consuming alcohol when taking Pari CR 37.5 Tablet, as it may cause excessive drowsiness and calmness.
  • The addiction/dependence potential of Pari CR 37.5 Tablet is very less.

Fact Box

Chemical Class
Phenylpiperidine Derivative
Habit Forming
No

Interaction with Drugs

Taking Pari with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Brand(s): Lizolan, Lidoford, Mapzolide
LIFE-THREATENING
Brand(s): Trima, Rimarex, Morex
LIFE-THREATENING
Brand(s): Rasalect, Relgin, Rasipar
LIFE-THREATENING
Brand(s): Rebotin
LIFE-THREATENING

Patient Concerns

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i am having anxiety disorder and panic attack I'm taking Pari Cr forte and Joykem 50 from past 9 months and I'm fine but when I don't take this tablets I get panic attack
Dr. Jyoti Kapoor Madan
Psychiatry
The medicines are to be tapered of gradually over several weeks.the combination of drugs need to be segregated and stopped. You should discus the same with your psychiatrist who has prescribed the medicines.
I have been diagnosing for panic attack and taking medicines Pari cr 37.5 mg nd sulpitac 100 mg and i have been taking tablets since 7 years please help me out or else tell me how long should i take this medicines
Dr. Jyoti Kapoor Madan
Psychiatry
Based on your clinical history, your doctor plans the type of medicine and it's dose and duration. For first episode of anxiety/ depression/ panic, the usual maintenance phase is 6 months of asymptomatic period, after which medicines can be gradually tapered. But treatment may need to continue longer depending on severity and frequency of episodes. Treatment for Recurrent Depressive Disorder , psychotic disorders, Bipolar Affective Disorder and OCD usually lasts for much longer.To monitor any potential side effects and to take any decision to change medication or stop them, several factors have to be taken in account for which regular follow up with your psychiatrist is important. For second opinion, seek a proper consultation with another psychiatrist and take along your previous prescriptions.
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User Feedback


FAQs

Q. After how many days of taking Pari will I start feeling better?

You may start to see an improvement in your symptoms after 1-2 weeks of starting the treatment. In case you do not see any improvement, do not stop the medicine and consult your doctor. It may take around 4-6 weeks to see the full benefits of the medicine.

Q. I feel that my symptoms have worsened after having started taking Pari. Can I stop it on my own or do I need to consult the doctor?

No, do not stop taking Pari abruptly, without consulting your doctor. This is a common problem with Pari that initially you may feel that your symptoms have worsened but the benefits start appearing after 1-2 weeks. If the worsening does not improve even after 1-2 weeks, you must consult your doctor.

Q. Can Pari affect my sex life?

Yes, Pari use may affect your sex life. It can cause decreased sexual desire and inability to reach orgasm in both men and women. Additionally, men may even experience abnormal erection and ejaculation.

Q. What is the effect of Pari on children?

Pari should not be used in children under 18 years of age. The reason being, patients under 18 have an increased risk of experiencing side effects such as suicidal thoughts, aggression, oppositional behavior and anger when they take Pari. If your doctor has prescribed Pari for your child and you are worried about these side effects, discuss it with your doctor.

Q. I have been taking tamoxifen for breast cancer. Can I take Pari with it?

No, you should not take Pari if you are receiving tamoxifen. Tamoxifen often causes hot flashes (episodes of feeling extremely hot), which can be treated with Pari. But Pari may reduce the effectiveness of tamoxifen and can lead to recurrence of breast cancer.

Q. Do I need to be careful while taking Pari if I am a diabetic?

Yes, you need to be careful while taking this medicine if you are a diabetic. Pari may alter your blood sugar levels and your dose of insulin or antidiabetic medicines may need adjustment. Talk to your doctor regarding this and keep a regular check on your blood sugar levels.

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1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover all possible side effects, drug interactions or warnings or alerts. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

  1. Stahl SM, editor. Paroxetine. In: Stahl's Essential Pschopharmacology: Prescriber's Guide. 5th ed. New York, New York: Cambridge University Press; 2014. pp. 513-19.
  2. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 1060-69.
  3. Paroxetine.Miami, Florida:Noven Therapeutics; 2003 [revised 06-2013]. [Accessed 25 Mar 2019] (online) Available from:External Link
  4. Chaves RG, Lamounier GA. Breastfeeding and maternal medications. J Pediatr (Rio J). 2004;80(5 Suppl):S189-S198. [Accessed 25 Mar. 2019] (online) Available from:External Link
  5. Paroxetine. South Ruislip, Middlesex: Aurobindo Pharma - Milpharm Ltd.; 2008 [revised 25 Nov. 2018]. [Accessed 25 Mar. 2019] (online) Available from:External Link
  6. Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006. Paroxetine. [Updated 2019 Oct 23]. [Accessed 20 Feb. 2020] (online) Available from:External Link
  7. Central Drugs Standard Control Organisation (CDSCO). [Accessed 25 Mar. 2019] (online) Available from:External Link

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