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MRP: Rs. 156451 for 1 bottle(s) (50 ML infusion each)
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Composition for PAMIGLAN

Pemetrexed(500 mg)

food interaction for PAMIGLAN

alcohol interaction for PAMIGLAN

pregnancy interaction for PAMIGLAN

lactation interaction for PAMIGLAN

It can be taken with or without food, but it is better to take it at a fixed time.
Interaction with alcohol is unknown. Please consult your doctor.
It is unsafe to use during pregnancy.
Human and animal studies have shown adverse effects on the foetus. The potential benefits may warrant the use in pregnant women despite potential risks. Please consult your doctor.
Unknown. Human and animal studies are not available. Please consult your doctor.


Pemetrexed(500 mg)


Pamiglan 500mg infusion is used in the treatment of a type of lung cancer called non-squamous non-small cell lung cancer and in the treatment of another cancer called malignant pleural mesothelioma (a type of cancer that originates from the lining of the various organs of the body).

How it works

Pamiglan 500mg infusion belong to class of chemotherapy drugs called folate antimetabolites. It disrupts certain metabolic processes essential for cancer cell replication and multiplication.

Common side effects

Nausea, Muscle pain, Joint pain, Shortness of breath, Chest pain, Constipation, Depression, Fatigue, Dizziness, Headache, Insomnia, Decreased white blood cell count, Loss of appetite, Mood changes, Vomiting, Weight loss


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Expert advice for PAMIGLAN

  • You should always take vitamin B12, folic acid, and corticosteroids along with pemetrexed.
  • Tell your doctor, if you have been recently vaccinated. 
  • Tell your doctor if you have heart disease or history of heart disease, kidney or liver disorder.
  • Your blood samples will be evaluated to check kidney and liver function and blood cell count before each pemetrexed infusion.
  • If you have had or are going to have radiation therapy, tell your doctor, as there may be an early or late radiation reaction with pemetrexed. 
  • Consult your doctor regarding contraception and ensure to use contraception when on treatment with Pemetrexed and up to 6 months thereafter.
  • Tell your doctor if you are pregnant or think you may become pregnant or breast-feeding.

Frequently asked questions for PAMIGLAN


Q. Is pemetrexed a vesicant?
No. Pemetrexed is not a vesicant.
Q. Is pemetrexed a chemotherapy/ cytotoxic?
Yes. Pemetrexed is chemotherapy and a cytotoxic drug.
Q. Is pemetrexed safe?
Pemetrexed is safe if used at prescribed doses for the prescribed duration as advised by your doctor.
Q. Does pemetrexed cause hair loss?
Yes. Pemetrexed is a prescription chemotherapy medication and hair loss is one of the possible side effects.


Content on this page was last updated on 26 April, 2014, by Dr. Varun Gupta (MD Pharmacology)