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27 Dec 2019 | 01:09 PM (IST)
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Palip XR 1.5mg Tablet


Overview

Introduction

Palip XR 1.5mg Tablet is a prescription medicine used in the treatment of schizophrenia (a mental disorder that can result in hallucinations or delusions and also adversely affects a person’s ability to think and behave) and mania.

Palip XR 1.5mg Tablet may be taken with or without food. However, it is advised to take it at the same time each day as this helps to maintain a consistent level of medicine in the body. Take this in the dose and duration as advised by your doctor and if you have missed a dose, take it as soon as you remember. It is important that this medication is not stopped suddenly without talking to your doctor as it may worsen your symptoms. However, discontinue this medicine immediately if you experience Neuroleptic malignant syndrome (NMS), characterized by fever, muscle rigidity, and altered consciousness.

Some common side effects of this medicine includes nystagmus (involuntary eye movement) and tremor. It also causes dizziness and sleepiness, so do not drive or do anything that requires mental focus until you know how this medicine affects you.

You should be cautious if you are using this medicine as it may increase the risk of developing diabetes, so it is better to monitor glucose regularly. Inform your doctor if you develop any unusual changes in mood or behavior, new or worsening depression, or suicidal thoughts while taking this medicine.

Uses of Palip Tablet

Side effects of Palip Tablet

Common
  • Dizziness
  • Abnormal involuntary movements
  • Sleepiness
  • Nystagmus (involuntary eye movement)
  • Tremor

How to use Palip Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Palip XR 1.5mg Tablet may be taken with or without food, but it is better to take it at a fixed time.

How Palip Tablet works

Palip XR 1.5mg Tablet is an atypical antipsychotic. It works by affecting the levels of chemical messengers (dopamine and serotonin) to improve mood, thoughts and behavior.

Safety Advice

Alcohol
UNSAFE
Palip XR 1.5mg Tablet may cause excessive drowsiness with alcohol.
Pregnancy
CONSULT YOUR DOCTOR
Palip XR 1.5mg Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breastfeeding
CONSULT YOUR DOCTOR
Palip XR 1.5mg Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Driving
UNSAFE
Palip XR 1.5mg Tablet may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Kidney
CAUTION
Palip XR 1.5mg Tablet should be used with caution in patients with kidney disease. Dose adjustment of Palip XR 1.5mg Tablet may be needed. Please consult your doctor.
Use of Palip XR 1.5mg Tablet is not recommended in patients with end-stage kidney disease.
Liver
CAUTION
Palip XR 1.5mg Tablet should be used with caution in patients with severe liver disease. Dose adjustment of Palip XR 1.5mg Tablet may be needed. Please consult your doctor.
Limited information is available on the use of Palip XR 1.5mg Tablet in these patients. No dose adjustment is recommended in patients with mild to moderate liver disease.

Alternate Brands

For informational purposes only. Consult a doctor before taking any medicines.
Palip XR 1.5mg Tablet
₹3.7/Tablet
Paliris 1.5mg Tablet
Sun Pharmaceutical Industries Ltd
₹2.71/Tablet
save 27%

Quick Tips

  • You can take paliperidone with or without breakfast, however, same pattern to be followed during the entire treatment.
  • Inform your doctor if you have known cardiovascular disease or family history of QT prolongation and if you are taking medicines that may prolong the QT interval.
  • Discontinue and inform you doctor immediately if you experience Neuroleptic Malignant Syndrome (NMS), characterised by hyperthermia (fever), muscle rigidity, autonomic instability, altered consciousness, and elevated serum creatine levels.
  • Inform your doctor if you have a swallowing, stomach or intestinal disorder that reduces your ability to swallow or pass foods by normal bowel movements.
  • You may suffer from tardive dyskinesia characterized by rhythmical, involuntary movements, predominantly of the tongue and/or face. Inform you doctor if you experience such symptoms.
  • You may suffer from priapism (prolonged and/or painful erection), inform your doctor if you experience such symptoms.
  • Do not drive or operate machinery as paliperidone may have some nervous effects and may cause visual disturbances. 
  • If you are a patient with diabetes, or with schizophrenia, taking paliperidone may increase the risk of developing diabetes. You should monitor glucose regularly while on paliperidone treatment.
  • Seek immediate medical attention if the thoughts of suicide occur when on paliperidone therapy.
  • Tell your doctor if you are or planning to become pregnant or are breastfeeding.

Interaction with Drugs

Taking Palip with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Brand(s): Clowil, Odis, Kamestin
LIFE-THREATENING
Brand(s): Fungis, EF Z, Rocflu
LIFE-THREATENING
Brand(s): Indizole, Itracip, Itraspan
LIFE-THREATENING
Brand(s): Canticid
LIFE-THREATENING

Patient Concerns

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How to treat erectile dysfunction with schizophrenia
Dr. Deepak Kumar Soni
Ayurveda
https://www.1mg.com/otc/himalaya-confido-tablet-otc90667One ?one tablet morning & evening after taking food , use at least 1-2 months
Metolar XR 50 what is use of the tablet
Dr. Manju Singh
Homeopathy
Please consult with allopathy doctor.
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Do you have any questions related to Palip XR 1.5mg Tablet ?

User Feedback


FAQs

Q. Is paliperidone the same as risperidone?

Paliperidone gets converted to risperidone in the body and thus exerts similar actions

Q. Is Palip a narcotic?

No, Palip is not a narcotic

Q. Is Palip an atypical antipsychotic?

Yes, Palip is an atypical antipsychotic

Q. How is Palip metabolized?

Palip is metabolized to its active metabolite risperidone by the CYP family of metabolizing enzymes

Q. Does Palip cause weight gain?

Yes, Palip is known to cause weight gain

Q. Does Palip cause erectile dysfunction?

Palip may cause priapism (prolonged and/or painful erection), which may contribute to erectile dysfunction. Please follow your doctor's advice regarding its use

Q. How long does Palip stay in your system?

Oral Palip may take 5 days to clear off from your body/system, whereas the injection may take around 4 to 8 months to clear off from your body/system.

Related Products

Disclaimer: 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover all possible side effects, drug interactions or warnings or alerts. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.
References
  1. Stahl SM, editor. Paliperidone. In: Stahl's Essential Pschopharmacology: Prescriber's Guide. 5th ed. New York, New York: Cambridge University Press; 2014. pp. 503-508.
  2. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 1047-48.
  3. Paliperidone. High Wycombe, Bucks: Janssen-Cilag Ltd.; 2007 [revised 13 Sep. 2018]. [Accessed 23 Jan. 2019] (online) Available from:External Link
  4. Paliperidone. Vacaville, California: ALZA Corporation; 2006. [Accessed 25 Mar 2019] (online) Available from:External Link
  5. U.S. National Library of Medicine. Paliperidone. [Accessed 25 Mar 2019] (online) Available from:External Link
  6. Drugs.com. Paliperidone. [Accessed 25 Mar. 2019]. (online) Available from:External Link
  7. Paliperidone. High Wycombe, Bucks: Janssen-Cilag Ltd.; 2012 [revised 13 Sep. 2018]. [Accessed 25 Mar. 2019] (online) Available from:External Link
  8. Central Drugs Standard Control Organisation (CDSCO). [Accessed 25 Mar. 2019] (online) Available from:External Link
Manufacturer/Marketer Address
Chinubhai Centre, Off. Nehru Bridge, Ashram Road, Ahmedabad - 380009. Gujarat. India.
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