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MMST, MBBS
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MD (Pharmacology), MBBS
Last updated on:
27 Aug 2019 | 12:46 PM (IST)
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Palbace Capsule

Prescription Required
Manufacturer
SALT COMPOSITION

Overview

Introduction of Palbace Capsule

Palbace Capsule is used to treat patients with certain types of breast cancer (estrogen receptor-positive, human epidermal growth factor receptor 2-negative) which have spread to other organs. It is given together with hormonal anticancer therapies.

Palbace Capsule is taken in a dose as advised by the doctor. The duration of treatment varies on the basis of your need and response to treatment. You may be asked for regular blood tests while taking this medication. It is better to inform doctor if you notice symptoms of infection like fever, chills and weakness. You should use effective contraception method to prevent pregnancy while taking this medicine

It may cause dizziness, so avoid driving or any activity requiring mental focus until you know how it affects you. Most of the side effects of Palbace Capsule is reversible and disappear when the medicine is stopped. Neutropenia is a well-recognized adverse effect, in which the number of your white blood cells get reduced and your immune system gets weakened. As a result, you may be at greater risk of getting an infection. However, this side effect disappears rapidly once you stop taking the medicine.

Palbace Capsule side effects

Common
  • Fatigue
  • Hair loss
  • Rash
  • Vomiting
  • Diarrhea
  • Nausea
  • Decreased appetite
  • Infection
  • Increased white blood cell count
  • Stomatitis (Inflammation of the mouth)
  • Anemia (low number of red blood cells)
  • Weakness
  • Fever

How to use Palbace Capsule

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Palbace Capsule is to be taken with food.

How Palbace Capsule works

Palbace Capsule is an anti-cancer medication. Cyclin dependent kinase 4 and 6 (chemical messengers) are downstream of signaling pathways which lead to the proliferation of cells. This medicine works by inhibiting cyclin dependent kinase 4 and 6, thus arrests the cancer cell cycle (cell growing process). It also targets the estrogen (hormone) receptor-positive breast cancer cells by disrupting the cell cycle.

Palbace Capsule related warnings

Alcohol
There is no data available. Please consult doctor before consuming the drug.
Pregnancy
CONSULT YOUR DOCTOR
Palbace Capsule is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
Lactation
CONSULT YOUR DOCTOR
Palbace Capsule is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Driving
There is no data available. Please consult doctor before consuming the drug.
Kidney
There is no data available. Please consult doctor before consuming the drug.
Liver
There is no data available. Please consult doctor before consuming the drug.

Alternate Brands

For informational purposes only. Consult a doctor before taking any medicines.
No alternate brands found for this medicine

Expert Advice

  • Take it with food, preferably at the same time every day. 
  • If you forget to take the medicine or vomit, skip the missed dose and follow a regular schedule. Do not take a double dose to make up missed dose
  • Use effective contraception method to prevent pregnancy while taking this medicine.
  • It may cause dizziness. Avoid driving or any activity requiring mental focus until you know how it affects you.
  • You may be asked for regular blood tests while taking this medication. Inform your doctor if you notice symptoms of infection like fever, chills, and weakness.
  • Inform your doctor if you are pregnant, planning pregnancy or breastfeeding.
  • Do not stop taking the medication without talking to your doctor first.

Patient Concerns

Questions Related to Palbace

arrow
Isn't Imodium capsule banned ?
Dr. Ankur Gupta
General Physician
Imodium is not banned but should be taken carefully as it can cause paralytic ilius or can land patient into abdominal sepsis . it's taken in loose motions to stop them instantly . But should only be taken after a doctor's opinion and guiadance.
Hergrace capsule purpose and contains
Dr. Suman Rao
Gynaecologist
There are n no. Of things in this capsule. All are either multivitamins or multiminetals. There is no specific indication for this
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Do you have any questions related to Palbace Capsule?

User Feedback


FAQs

Q. What kind of medicine is Palbace?

Palbace is an anti-cancer medicine. Palbace blocks proteins known as cyclin-dependent kinase inhibitors. Blocking these proteins can slow down the growth of cancer cells and delay the progression of the cancer.

Q. How long do I have to take Palbace?

The duration of treatment varies from person to person. Your doctor will decide the number of cycles you need to receive based on your condition, response to treatment and your tolerance to side effects. Your doctor may decrease your dose or stop your treatment temporarily or permanently if you experience certain side effects.

Q. Are the side effects of Palbace irreversible?

No, most of the side effects are reversible and disappear when the medicine is stopped. Neutropenia is a well-recognized adverse effect of Palbace in which the number of your white blood cells get reduced and your immune system gets weakened. As a result, you may be at greater risk of getting an infection while you are taking Palbace. However, this side effect disappears rapidly once you stop taking the medicine.

Q. Does treatment with Palbace require monitoring of blood counts?

Yes, blood tests are important since this medicine can lower your blood counts. The regular blood tests check the effect of Palbace on your blood cells (white blood cells, red blood cells, and platelets). These tests should be done at the beginning of each chemotherapy cycle, on the 15th day of the first 2 cycles, and as clinically indicated.

Q. How should I take Palbace?

Generally, Palbace is taken once daily for 21 consecutive days followed by 7 days off treatment to add up a complete cycle of 28 days. Take this medicine with food and at the same time each day. Swallow the whole capsules. Do not open, chew, or crush them. Do not take the capsules that are broken or cracked. If you vomit after taking Palbace, do not take another dose and continue your regular dosing schedule.

Q. Do I need to use birth control method while using Palbace?

Women of childbearing potential who are receiving Palbace and their partners should use adequate contraceptive methods (e.g. double-barrier contraception such as condom and diaphragm). These methods should be used during therapy and for at least 3 weeks after completing therapy for females. Men who are on Palbace therapy should use birth control methods for at least 14 weeks after completing the therapy.

Q. Does Palbace affect fertility?

Male fertility may be affected during treatment with Palbace. Thus, men may consider sperm preservation prior to beginning therapy with Palbace.

Q. What are the serious side effects of Palbace?

The serious side effects of Palbace include shortness of breath, dizziness, weakness, unusual bleeding or bruising or nosebleeds. It may also cause fever, chills or signs of infection and fast, irregular or pounding heartbeat. If you experience any of these symptoms, call your doctor immediately or get emergency medical treatment.
Disclaimer: 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover all possible side effects, drug interactions or warnings or alerts. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.
References
  1. Palbociclib. New York, New York: Pfizer Labs; 2015 [revised 31 Mar. 2017]. [Accessed 25 Jun. 2019] (online) Available from:External Link
  2. Central Drugs Standard Control Organisation (CDSCO). [Accessed 26 Mar. 2019] (online) Available from:External Link
Manufacturer/Marketer Address
The Capital, 1802, 18th Floor , Plot No. C-70, ‘G’ Block , Bandra Kurla Complex, Bandra East , Mumbai – 400051.
A licensed pharmacy from your nearest location will deliver Palbace Capsule. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your prescription and the availability of this medicine.
78375
MRP95000  17% OFF
21 capsules in 1 bottle
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