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Composition for PADMOL

Paracetamol(125 mg),Promethazine(5 mg)

food interaction for PADMOL

alcohol interaction for PADMOL

pregnancy interaction for PADMOL

lactation interaction for PADMOL

There is no data available. Please consult doctor before consuming the drug.
Padmol 5mg/125mg syrup may cause excessive drowsiness and calmness with alcohol.
Padmol 5mg/125mg syrup may be unsafe to use during pregnancy.
Either animal studies have shown adverse effect on fetus and there are no human studies or studies in human and animals are not available. It should be given only if potential benefits justifies risk to the fetus. Please consult your doctor.
Unknown. Human and animal studies are not available. Please consult your doctor.


Paracetamol(125 mg)


Paracetamol is used for the relief of mild to moderate pain in conditions such as headache (including migraine), toothache, ear pain, joint pain, pain during menstruation, fever, feverish colds, and flu.

How it works

Paracetamol belongs to class of medications called analgesics (painkiller) and antipyretics (fever reducing). Paracetamol reduces pain by increasing the pain threshold. It reduces fever by acting on the temperature-regulating region of brain, resulting in increased blood flow across the skin, sweating and heat loss.

Common side effects

Skin redness, Allergic reaction, Shortness of breath, Running nose, Nausea, Liver injury, Abnormal blood cell count, Facial swelling, Blisters on skin
Promethazine(5 mg)


Promethazine is used for treatment of allergies to the upper respiratory tract and skin including symptoms of sneezing, runny and itchy nose and eye irritation and red, raised, itchy skin rash. It is also used to prevent and control nausea, vomiting and pain which may occur after surgery; to prevent motion sickness. It also used as a short-term sedative.

How it works

Promethazine belongs to the group of medicines called antihistamines. It also has additional anti-emetic, central sedative and anti-cholinergic properties. It acts by blocking a natural substance called histamine that your body produces during an allergic reaction.

Common side effects

Nightmare, Pale red skin, Itchy rash, Rash, Abdominal cramp, Abnormal liver function tests, Altered heart rate, Blurred vision, Confusion, Decreased blood pressure, Diarrhoea, Disorientation (alteration of mental status), Dizziness, Drowsiness, Dry mouth, Gastric irritation, Headache, Hypersensitivity reaction, Inability to empty the urinary bladder, Itching, Loss of appetite, Muscle cramp, Nausea, Restlessness, Vomiting, Fatigue


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Expert advice for PADMOL

  • Do not take if you are taking any other products that contain paracetamol, or are allergic to paracetamol or any of the other ingredients.
  • Do not take paracetamol if you drink three or more alcoholic beverages every day.
  • Consult your doctor immediately if you have any skin reaction such as skin reddening, blisters, or rash.
  • Do not take paracetamol without consulting your doctor if you are pregnant or breast feeding.

Frequently asked questions for PADMOL


Q. Is paracetamol safe/ banned/ available in India?
Paracetamol (also known as acetaminophen, crocin, dolo, calpol, pacimol) is an over-the-counter drug available in India. It is generally safe if used at prescribed doses for the prescribed duration as advised by your doctor.
Q. Is paracetamol a painkiller/ used for cold?
Paracetamol is used to relieve mild to moderate pain associated with cold and flu, as well as fever.
Q. Does paracetamol make you drowsy / sleepy? 
Paracetamol does not cause drowsiness. However, paracetamol is available in combination with cough and cold medicines (eg. cetirizine, chlorpheniramine), which may cause drowsiness or sleepiness.
Q. Is paracetamol an NSAID/ antibiotic?
Paracetamol is a anti-pyretic (anti-fever), anti -inflammatory drug, which belongs to the category of non-steroidal anti-inflammatory drug (NSAID). However, unlike other NSAIDS, paracetamol can relieve only mild to moderate pain.
It is not an antibiotic.
Q. Can I take crocin with cetirizine/ aceclofenac/ amoxicillin/ codeine/ tramadol/ warfarin/ erythromycin/ antibiotics?
Yes, paracetamol (available as crocin) can be taken with all of these drugs. Caution is advised when crocin is to be used with warfarin. However, always consult your doctor regarding combined use of crocin with any other drug.
Q. Can I take crocin with ibuprofen/naproxen/other NSAID?
Paracetamol (available as crocin) is available over-the-counter in combination with ibuprofen/naproxen/other NSAID. However, always consult your doctor regarding combined use of crocin with any other drug.
Q. Does paracetamol cause death?
Paracetamol on overdose can severely damage the liver and cause death. No more than 4 grams should be consumed in one day. Always consult your doctor regarding use of paracetamol.
Q. Can calpol make babies/ toddlers sleep/ help in teething pain?
Calpol can relieve pain in infants and children; it does not make them sleep.


Q. Is promethazine or Promethazine DM syrup a narcotic/opiate/pain killer?
Promethazine is antihistaminic drug and not a narcotic/opiate/pain killer. Patient should follow the advice of doctor regarding its use.
Q. Is promethazine over the counter?
No, it is available with doctor’s prescription only.
Q. Can I take promethazine for a hangover/sore throat/ nausea/stomach flu/cramps/toothache/ headache/ cough/pain?
Promethazine is used for treatment of symptoms of allergies, but not used for  hangover, sore throat, stomach flu, cramps, toothache, headache and cough. Patient should follow the advice of doctor regarding its use.
Q. Can I take promethazine with Nyquil/ codeine and ibuprofen/ Tylenol/ oxycodone/ Benadryl/ Dayquil/ Zofran/codeine and Nyquil/Xanax?
Yes, but taking other medicines may alter the effects of promethazine. Always consult your doctor for the change of dose regimen or an alternative drug of choice that may strictly be required.
Q. Does promethazine/Promethazine VC have codeine in it?
No, it does not contain codeine in it.
Q. Does promethazine or Promethazine DM make you sleepy/ get you high/make you tired?
Promethazine may cause these side effects which are not serious. However, always consult your doctor if you experience any of these side effects.


Content on this page was last updated on 30 August, 2014, by Dr. Varun Gupta (MD Pharmacology)