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Composition for NORFLOX M LB

Norfloxacin(500 mg),Metronidazole(400 mg),Lactobacillus(NA)

food interaction for NORFLOX M LB

alcohol interaction for NORFLOX M LB

pregnancy interaction for NORFLOX M LB

lactation interaction for NORFLOX M LB

Avoid Norflox m lb tablet with grapefruit juice.
Norflox m lb tablet may cause symptoms such as flushing, increased heartbeat, nausea, thirst, chest pain and low blood pressure with alcohol (Disulfiram reactions).
Norflox m lb tablet may be unsafe to use during pregnancy.
Either animal studies have shown adverse effect on fetus and there are no human studies or studies in human and animals are not available. It should be given only if potential benefits justifies risk to the fetus. Please consult your doctor.
Unknown. Human and animal studies are not available. Please consult your doctor.


Norfloxacin(500 mg)


Norfloxacin is used in the treatment of adults with urinary tract infections, both uncomplicated (cystitis) and complicated urinary tract infections, sexually transmitted diseases (gonorrhea), genital infection, prostate infection (prostatitis), infections of the stomach or intestines (travelers’ diarrhea) and eye infection. It acts by inhibiting bacterial deoxyribonucleic acid synthesis and thus, killing the bacteria.

How it works

Norfloxacin belongs to class of drugs called flouroquinolone antibiotics. Norfloxacin inhibits bacterial reproduction by inhibiting DNA formation, thereby killing the bacteria.

Common side effects

Decreased urination, Facial swelling, Allergic reaction, Lip swelling, Skin rash, Itching, Urticaria, Shortness of breath, Anxiety, Muscle pain, Joint pain, Bruise, Bleeding, Blisters on skin, Convulsion, Dark colored urine, Dizziness, Diarrhoea, Headache, Hoarseness of voice, Loss of consciousness, Fainting, Restlessness, Stomach cramp, Tachycardia, Tremor, Uncoordinated body movements, Vomiting, Abdominal pain, Yellow discoloration of skin, Yellow discoloration of eye, Weakness, Fever, Confusion, Hallucination, Heartburn, Nausea
Metronidazole(400 mg)


Metronidazole is used to treat infections of the gum and dental cavity, pelvic area, brain, lung, bones, stomach, intestines, genital tract and blood. It is used to treat pressure sores and leg ulcers and prevent infections after surgery.

How it works

Metronidazole belongs to a class of medicines called as nitroimidazole antibiotics. It works by inhibiting energy production and killing the bacteria and parasites that cause infections in the body.

Common side effects

Allergic reaction, Itching, Skin rash, Joint pain, Bitter taste, Dark colored urine, Dry mouth, Furry tongue, Loss of appetite, Mouth irritation, Throat irritation, Nasal congestion, Stomach upset, Numbness, Tingling sensation, Weakness, Fever, Vomiting, Diarrhoea


Lactobacillus (Lactobacillus acidophilus, L. bulgaricus, L.casei, L. rhamnosus.)  is used in the following conditions:
  • Prevention and treatment of diarrhea caused by rotavirus infection in children, traveler’s diarrhea in adults and diarrhea associated with hospitalization, antibiotic treatments and cancer chemotherapy.
  • Irritable bowel syndrome, and ulcerative colitis.
  • As a combination with other medications in the treatment of Helicobacter pylori infections that cause stomach ulcers.
  • Infections of vagina caused by bacteria (bacterial vaginosis) or yeast.
  • Prevention and treatment of skin diseases in infants and children who are allergic to cow’s milk.
  • Prevention of lung infections in children aged between 1 to 6 years.
  • Treatment of high cholesterol, sugar intolerance.
  • Boost to immune system.

How it works

Lactobacillus is a family of useful bacteria found naturally in the mouth, intestine and vagina. Products containing lactobacillus are used as ‘probiotics’ that help restore the levels of these good bacteria. It provides health benefits by assisting break down of food and absorption of nutrients; also stimulating the body’s immune response. It also produces substances that suppress or kill harmful bacteria and creates an unfavorable environment for the growth of disease causing bacteria.

Common side effects

Flatulence, Abdominal bloating


No substitutes found

Expert advice for NORFLOX M LB

  • Avoid  norfloxacin if you have  known history of muscle weakness (myasthenia gravis). It may further increase the muscle weakness.
  • Do not drink or eat a lot of caffeine-containing products such as coffee, tea, energy drinks, cola, or chocolate -may increase nervousness, sleeplessness, heart pounding, and anxiety.
  • Drink plenty of water or other fluids every day while you are taking norfloxacin.
  • Do not start or continue the norfloxacin and consult your doctor if you have allergies to medicines, foods, or other substances.
  • Avoid unnecessary or prolonged exposure to sunlight or ultraviolet light (tanning beds and sunlamps) and to wear protective clothing, sunglasses, and sunscreen. Norfloxacin may make your skin sensitive to sunlight or ultraviolet light. If your skin becomes reddened, swollen, or blistered, consult your doctor.
  • Take norfloxacin at least one hour before or at least two hours after taking antacids (aluminum or magnesium hydroxide), didanosine, sucralfate, supplements or multivitamins that contain iron or zinc, meal or ingestion of milk and/or other dairy products. 
  • Norfloxacin can cause dizziness and light-headedness and, therefore, caution has to be taken before operating an automobile or machinery or engaging in activities requiring mental alertness and coordination.
  • Norfloxacin is associated with an increased risk of tendinitis and tendon rupture. it should be used carefully in patients over 60 years of age, in patients taking steroids corticosteroid drugs, in patients with kidney, heart or lung transplants to minimize this risk.

Frequently asked questions for NORFLOX M LB


Q. Is norfloxacin/ norflox tz/ norflox 400/ norilet/ norilet 400 same as ciprofloxacin?
No, however they belong to same class of medication called as fluoroquinolones and act by same mechanism but differ in absorption, metabolism and excretion.
Q. Is norfloxacin/ norflox tz/ norflox 400/ norilet/ norilet 400 same as penicillin/broad spectrum antibiotic?
No, they belong to same class of medication called as fluoroquinolones and they act by different mechanism.
 Q. Is norfloxacin/ norflox tz/ norflox 400/ norilet/ norilet 400 used for treatment of diarrhea and UTI?
Yes, however it depends on microorganism involved and effectiveness. Always consult your doctor on this regards.
Q. Is norfloxacin sulfa based / a penicillin/ an antibiotic?
No. Norfloxacin belong to a different group of antibiotics called fluoroquinolones. It does not contain penicillin or sulpha.


Q. Is metronidazole safe?
Yes, metronidazole is a relatively safe drug if used in prescribed dose and for prescribed duration as advised by your doctor.
Q. What is metronidazole?
 Metronidazole is an antibiotic.
Q. Is it antibiotic or pain killer?
Metronidazole is an antibiotic and not pain killer.

Q. What it is used for?
It is used for infections of the dental cavity, ears, sinus, throat, lungs, stomach, intestine, brain and bones.
Q. Is metronidazole same as Flagyl?
Yes. Flagyl is a branded medicine containing metronidazole.
Q. Does metronidazole cure STDs or yeast infections?
Metronidazole cures genital infections like bacterial vaginosis and gonorrhea. It does not cure chlamydia or vaginal yeast infections.
Q. Does metronidazole affect birth control?
There is no evidence of metronidazole affecting contraception. Please consult your doctor to confirm whether you require a secondary birth control measure while taking metronidazole.
Q. Is metronidazole an OTC product?
No, metronidazole is not an OTC product.
Q. Can metronidazole cause nausea, vomiting, constipation or irregular monthly periods?
Metronidazole may cause nausea, vomiting, constipation or upset stomach. However, there is no evidence of metronidazole affecting monthly periods. If you notice any such symptoms, please consult your doctor.


Q. Is lactobacillus/Lactobacillus acidophilus vegan/ dairy free?
Some products of lactobacillus/Lactobacillus acidophilus contain dairy products and may not be suitable for vegans. Please refer to package insert of the prescribed brand before use.
Q. Is lactobacillus good or bad/pathogenic?
Lactobacillus is a group of ‘good’ bacteria that provide several health benefits. It is not among the disease causing (pathogenic) bacteria.
Q. Is lactobacillus and Lactobacillus acidophilus same?
Lactobacillus acidophilus is a species of lactobacillus bacteria. Their role as a probiotic in the maintenance of good health is the same.
Q. Is lactobacillus gram negative?
Lactobacillus is a gram positive bacteria.
Q. Is lactobacillus motile?
Certain species or strains of lactobacillus are motile.
Q. Is Lactobacillus acidophilus good for yeast infections/can I take Lactobacillus acidophilus for yeast infections?
Yes. Lactobacillus has been regarded beneficial in the treatment of yeast infections of the vagina.
Q. Can I take Lactobacillus acidophilus for bad breath?
The benefits of Lactobacillus acidophilus in improving bad breath have not been established.
Q. How long can I take acidophilus for?
The duration of treatment with lactobacillus/Lactobacillus acidophilus depends upon the condition being treated and is decided by the doctor.
Q. Can you take lactobacillus with antibiotics?
Concomitant use of lactobacillus with antibiotics can lower its effectiveness. Products containing lactobacillus should be taken at least 2 hours before or after antibiotics.
Q. Does lactobacillus cause/produce gas?
Yes. Gas and bloating is a side effect of lactobacillus. In most cases these mild side effects subside with continued use.
Q. Does lactobacillus cause UTI?
Lactobacillus is not known to cause urinary tract infections (UTI).
Q. Does Lactobacillus casei contain casein?
Lactobacillus casei is one of the species of lactobacillus and is used a probiotic. Some products of lactobacillus contain dairy products and may contain casein. Please refer to package insert of the prescribed brand before use.
Q. Does lactobacillus create CO2/produce alcohol?
Yes. Lactobacillus may produce carbon dioxide gas and alcohol as a part of its normal cellular process (metabolism).
Q. Does Lactobacillus acidophilus need to be refrigerated?
Dairy based Lactobacillus acidophilus products may need refrigeration. Please refer to package insert of the prescribed brand for instructions.


Content on this page was last updated on 12 May, 2014, by Dr. Varun Gupta (MD Pharmacology)