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Nitrolingual 0.4mg Spray
Prescription Required
Product introduction
Nitrolingual 0.4mg Spray is used to treat and prevent heart-related chest pain (angina). Angina occurs when the heart muscle is not getting enough blood. This medicine works by relaxing and widening blood vessels so blood can flow more easily to the heart. It has a very short-lived effect.
Nitrolingual 0.4mg Spray should be taken at the first sign of chest pain. It should be used in the dose and duration as advised by your doctor. Seek medical help immediately if your chest pain continues for more than 15 minutes. Some people may be advised to use this medicine prior to any exertional activity or exercise, which may precipitate angina.
The most common side effect of this medicine is a headache which may be severe. This can sometimes be helped by drinking plenty of fluids and avoiding alcohol. You may also experience lightheadedness, which could increase your risk of having a fall, and other side effects such as flushing, weakness, and increased heart rate.
Do not use this medicine if you are taking medicines to treat high blood pressure in your lungs (pulmonary hypertension), or erectile dysfunction; or if you have anemia or glaucoma (increased pressure inside the eye). Always tell your doctor what other health conditions you have and what other medicines you are taking. It is best not to drink alcohol with this medicine as it increases some of the side effects. If you are affected by dizziness, avoid driving. If you are pregnant, thinking about becoming pregnant, or breastfeeding, ask your doctor before taking this medicine.
Nitrolingual 0.4mg Spray should be taken at the first sign of chest pain. It should be used in the dose and duration as advised by your doctor. Seek medical help immediately if your chest pain continues for more than 15 minutes. Some people may be advised to use this medicine prior to any exertional activity or exercise, which may precipitate angina.
The most common side effect of this medicine is a headache which may be severe. This can sometimes be helped by drinking plenty of fluids and avoiding alcohol. You may also experience lightheadedness, which could increase your risk of having a fall, and other side effects such as flushing, weakness, and increased heart rate.
Do not use this medicine if you are taking medicines to treat high blood pressure in your lungs (pulmonary hypertension), or erectile dysfunction; or if you have anemia or glaucoma (increased pressure inside the eye). Always tell your doctor what other health conditions you have and what other medicines you are taking. It is best not to drink alcohol with this medicine as it increases some of the side effects. If you are affected by dizziness, avoid driving. If you are pregnant, thinking about becoming pregnant, or breastfeeding, ask your doctor before taking this medicine.
Uses of Nitrolingual Sublingual Spray
Benefits of Nitrolingual Sublingual Spray
In Treatment of Angina (heart-related chest pain)
Nitrolingual 0.4mg Spray helps in prevention as well as treatment of angina. Angina is a chest pain that is usually caused by narrowing of the blood vessels which supply your heart. This means your heart does not get enough oxygen. Nitrolingual 0.4mg Spray works quickly to relax the muscles and blood vessels in your heart so more blood (and oxygen) gets to your heart. This reduces the pain and discomfort that angina causes.
You should take this medicine at the first sign of chest pain. If the first tablet does not work, you can take a second tablet after 5 minutes. However, if your chest pain does not go away after 15 minutes, you should get urgent medical attention. This could be a sign of a heart attack. Nitrolingual 0.4mg Spray also helps prevent chest pain if taken before exercising or doing other strenuous activities.
You should take this medicine at the first sign of chest pain. If the first tablet does not work, you can take a second tablet after 5 minutes. However, if your chest pain does not go away after 15 minutes, you should get urgent medical attention. This could be a sign of a heart attack. Nitrolingual 0.4mg Spray also helps prevent chest pain if taken before exercising or doing other strenuous activities.
Side effects of Nitrolingual Sublingual Spray
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Nitrolingual
- Dizziness
- Headache
- Increased heart rate
- Flushing (sense of warmth in the face, ears, neck and trunk)
- Weakness
How to use Nitrolingual Sublingual Spray
To use the spray, open your mouth, lift your tongue and press the bottle button down firmly to spray the medicine under your tongue. Close your mouth after you have sprayed the dose. You should not shake the bottle before use. Nitrolingual 0.4mg Spray may be taken with or without food, but it is better to take it at a fixed time.
How Nitrolingual Sublingual Spray works
Nitrolingual 0.4mg Spray is a nitrate. It works by improving blood supply to heart and relaxing the blood vessels which decreases the oxygen demand of the heart and reduces its workload. It thus prevents/treats attacks of angina (chest pain). Relaxation of blood vessels lowers blood pressure.
Safety advice
Alcohol
UNSAFE
Consuming alcohol while taking Nitrolingual 0.4mg Spray may cause symptoms such as flushing, increased heart beat, nausea, thirst, chest pain and low blood pressure (Disulfiram reaction).
Pregnancy
SAFE IF PRESCRIBED
Nitrolingual 0.4mg Spray is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.
Breast feeding
SAFE IF PRESCRIBED
Nitrolingual 0.4mg Spray is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
Driving
UNSAFE
Nitrolingual 0.4mg Spray may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Kidney
SAFE IF PRESCRIBED
Nitrolingual 0.4mg Spray is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Nitrolingual 0.4mg Spray may not be needed in these patients. Please consult your doctor.
Liver
CONSULT YOUR DOCTOR
There is limited information available on the use of Nitrolingual 0.4mg Spray in patients with liver disease. Please consult your doctor.
All substitutes
For informational purposes only. Consult a doctor before taking any medicines.
No substitutes found for this medicine
Quick tips
- Nitrolingual 0.4mg Spray may cause dizziness or sleepiness. Do not drive or do anything that requires concentration until you know how it affects you.
- Do not consume alcohol while taking Nitrolingual 0.4mg Spray as it may cause increased dizziness.
- It may cause headaches which usually go away after a few days of continued treatment. Inform your doctor if it persists.
- You may develop tolerance to Nitrolingual 0.4mg Spray with time, meaning that the same dose may be less effective next time. Follow the prescribed dosing schedule to avoid this.
- Stop taking medications (prescribed for erectile dysfunction) like sildenafil or tadalafil while on treatment with Nitrolingual 0.4mg Spray as it may cause low blood pressure.
Fact Box
Chemical Class
Nitrates {Short acting}
Habit Forming
No
Therapeutic Class
CARDIAC
Action Class
NO Donors
Interaction with drugs
Taking Nitrolingual with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Brand(s): Joy On, One Up, Confidence
Life-threatening
Brand(s): Suvida Force, Tadagra, Tadafun
Life-threatening
Brand(s): Udzire
Life-threatening
Brand(s): Edafil
Life-threatening
Patient concerns
User feedback
Patients taking Nitrolingual 0.4mg Spray
Once A Day
67%
Thrice A Day
33%
What are you using Nitrolingual Sublingual Spray for?
Angina (heart*
67%
Others
33%
*Angina (heart-related chest pain)
How much was the improvement?
Excellent
67%
Average
33%
What were the side-effects while using Nitrolingual 0.4mg Spray?
No Side Effec*
100%
*No Side Effect
FAQs
Q. How long does it take for Nitrolingual 0.4mg Spray to act?
Nitrolingual 0.4mg Spray starts working very quickly. If the medicine is kept under the tongue, the effect starts 1-3 minutes later and reaches its maximum within 5 minutes.
Q. What effect does Nitrolingual 0.4mg Spray have on blood pressure?
Nitrolingual 0.4mg Spray decreases the blood pressure by relaxing the blood vessels, but is not recommended for the treatment of high blood pressure. The drop in blood pressure may cause lightheadedness, especially when changing your position suddenly.
Q. Does the effect of Nitrolingual 0.4mg Spray wear off after sometime?
Yes, excessive use of Nitrolingual 0.4mg Spray may cause tolerance which means that Nitrolingual 0.4mg Spray may lose its effectiveness on you. Therefore, usually the doctors prescribe the smallest dose required for effective relief of acute angina attack. This helps maintain the effectiveness of Nitrolingual 0.4mg Spray.
Q. What does too much Nitrolingual 0.4mg Spray do?
Excess Nitrolingual 0.4mg Spray may result in low blood pressure, sweating, nausea, vomiting, headache, weak and fast pulse. It may also cause weakness, lightheadedness on standing and the patient might even faint. The patient will require emergency medical treatment in such a case.
Q. Can I stop using Nitrolingual 0.4mg Spray as I feel better now?
Stopping Nitrolingual 0.4mg Spray suddenly may bring on attacks of angina, especially if you have been using it for several weeks or more. Talk to your doctor who will advise you to reduce the dose gradually over 4 to 6 weeks before you stop using it completely.
Q. Does Nitrolingual 0.4mg Spray stop heart attacks?
Nitrolingual 0.4mg Spray is prescribed to prevent attacks of heart-related chest pain (angina) in patients with coronary artery disease. In this disease the blood vessels (coronary arteries) which supply blood to the heart become narrowed because of which the heart has to work harder to get enough oxygen. Nitrolingual 0.4mg Spray prevents angina by relaxing the blood vessels so that the heart does not have to work very hard. Also, relaxation of coronary arteries increases the oxygen supply to the heart.
Q. Can I take sildenafil if I am taking Nitrolingual 0.4mg Spray?
No, you should not take Nitrolingual 0.4mg Spray if you have taken sildenafil. Taking these two medicines together may increase the risk of excessive fall in blood pressure, which is hazardous. Maintain a gap of at least 24 hours if you have to use Nitrolingual 0.4mg Spray after taking sildenafil.
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Disclaimer:
Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.References
- Michel T, Hoffman BB. Treatment of Myocardial Ischemia and Hypertension. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 747-55.
- Katzung BG, Chatterjee K. Vasodilator & the Treatment of Angina Pectoris. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 191, 195-97.
- Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 986-88.
- Nitroglycerin Sublingual Tablets. New York, New York: Parke-Davis; 2014. [Accessed 20 Mar. 2019] (online) Available from:
- Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006. Nitroglycerin. [Updated 2018 Oct 31]. [Accessed 19 Feb. 2020] (online) Available from:
- Central Drugs Standard Control Organisation (CDSCO). [Accessed 19 Mar. 2019] (online) Available from:
- Glyceryl trinitrate [Package leaflet: Information for the user]. Łyszkowice, Poland: Orifarm Manufacturing Poland Sp. z o.o.; 2022. [Accessed 03 Aug. 2023] (online) Available from:
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