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Composition for NISE

Diclofenac Topical(NA)

food interaction for NISE

alcohol interaction for NISE

pregnancy interaction for NISE

lactation interaction for NISE

It can be taken with or without food, but it is better to take Nise gel at a fixed time.
Interaction with alcohol is unknown. Please consult your doctor.
Nise gel may be unsafe to use during pregnancy.
Either animal studies have shown adverse effect on fetus and there are no human studies or studies in human and animals are not available. It should be given only if potential benefits justifies risk to the fetus. Please consult your doctor.
Nise gel is probably safe to use during breastfeeding. Please consult your doctor.


Diclofenac Topical(NA)


Nise gel is used locally in the treatment of painful conditions such as arthritis of joint (osteoarthritis), conditions of the joint arising from destruction of healthy body tissue by the body’s immune system (rheumatoid arthritis, ankylosing spondylitis), lower back pain, sprains or bone fractures, inflammation of joints (frozen shoulder, gout), pain and swelling over body.

How it works

Diclofenac belongs to class of medications called as non-steroidal anti-inflammatory drugs (NSAIDs). It works by blocking the production of a certain chemical substance in the body that causes pain, fever, and inflammation. 

Common side effects

Burning sensation, Tingling sensation, Skin rash


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Expert advice for NISE

  • Inform your doctor if you have diabetes, angina, blood clots, and high blood pressure, raised cholesterol or raised triglycerides, liver disorder of the red blood pigment (porphyria).
  • Tell your doctor if you had or need to have surgery.
  • Avoid direct contact of gel/ lotion with your eyes. In case of direct contact, wash your eyes with water immediately and seek immediate medical attention.
  • Tell your doctor if you are pregnant, planning to become pregnant or are breastfeeding. 
  • Do not use if you are allergic to diclofenac or any of its ingredients.
  • Do not use if you previously had allergic reaction (asthma, hives or a cold) due to aspirin or other pain killers.

Frequently asked questions for NISE

Diclofenac Topical

Q. Is diclofenac topical a blood thinner / controlled substance?
Diclofenac is a pain relieving medication and it does not significantly affect the function of platelets in blood; hence it is not a blood thinner. It is not a controlled substance as it does not have the potential for abuse or addiction.


Content on this page was last updated on 26 September, 2016, by Dr. Varun Gupta (MD Pharmacology)