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NEOTREXATE 2.5 MG TABLET

Tablet
MRP: Rs. 51.20 for 1 strip(s) (10 tablets each)
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Composition for NEOTREXATE

Methotrexate(2.5 mg)

food interaction for NEOTREXATE

alcohol interaction for NEOTREXATE

pregnancy interaction for NEOTREXATE

lactation interaction for NEOTREXATE

food
alcohol
pregnancy
lactation
It is better to take Neotrexate 2.5 mg tablet with food.
Taking Methotrxate with alcohol increases the risk of liver damage.
UNSAFE
Neotrexate 2.5 mg tablet is highly unsafe to use during pregnancy.
Human and animal studies have shown significant adverse effects on the foetus. Please consult your doctor.
UNSAFE
Neotrexate 2.5 mg tablet is probably unsafe to use during breastfeeding. Please consult your doctor.
UNSAFE

SALT INFORMATION for NEOTREXATE

Methotrexate(2.5 mg)

Uses

Neotrexate 2.5 mg tablet is used in the treatment of ovarian cancer, head and neck cancer, cervical cancer, testicular cancer., breast cancer, non-Hodgkin lymphoma (NHL), blood cancer, lung cancer, bone cancer and urinary bladder cancer.
It is also used in rheumatoid arthritis, psoriasis (silvery scaly skin rash) and ectopic pregnancy.

How it works

Neotrexate 2.5 mg tablet belongs to a class of drugs known as antimetabolites. Neotrexate 2.5 mg tablet is referred to as a cytotoxic, most commonly used to stop the growth of cells in tumors. It acts by decreasing the activity of the immune system by blocking several enzymes involved in the immune system,and affects the growth of cancerous cells.

Common side effects

Pain, Shortness of breath, Persistent cough, Increased sensitivity to light, Acne, Frequent urge to urinate, Liver enzyme increased, Abnormal red blood cell function, Allergic reaction, Drowsiness, Difficulty in speaking, Muscle pain, Joint pain, Blood in urine, Blood vessel inflammation, Blurred vision, Boils, Chills, Convulsion, Coordination disorder, Decreased libido, Diabetes, Diarrhoea, Dizziness, Difficulty in urination, Eye irritation, Fever, Hair loss, Headache, Infertility, Intestinal malabsorption, Decreased red blood cell count, Reduced blood platelets, Decreased white blood cell count, Limb swelling, Loss of appetite, Feeling of discomfort, Black and bloody stools, Metabolic disorder, Mood changes, Rash, Skin damage, Skin inflammation, Skin erosion, Skin flakes, Skin ulcer, Sore throat, Steven-johnsons syndrome, Stomach pain, Vaginal irritation, Vaginal swelling, Vaginal ulcers, Fatigue, Weakness, Softening of bones, Yellow discoloration of skin, Yellow discoloration of eye, Thought disorder, Nausea

Common Dosage for NEOTREXATE 2.5 MG TABLET

Patients taking NEOTREXATE 2.5 MG TABLET

  • 29%
    Once A Week
  • 23%
    Once A Day
  • 16%
    Twice A Week
  • 13%
    Thrice A week
  • 13%
    Twice A Day
  • 3%
    Twice A Month
  • 3%
    Alternate Day

SUBSTITUTES for NEOTREXATE

11 Substitutes
Sorted By
RelevancePrice
  • FOLITRAX 2.5 MG TABLET
    (10 tablets in strip)
    Ipca Laboratories Ltd
    Rs. 4.49/tablet
    Tablet
    Rs. 44.94
    save 12% more per tablet
  • ONCOTREX 2.5 MG TABLET
    (10 tablets in strip)
    Sun Pharmaceutical Industries Ltd
    Rs. 4.47/tablet
    Tablet
    Rs. 44.73
    save 13% more per tablet
  • IMUTREX 2.5 MG TABLET
    (10 tablets in strip)
    Cipla Ltd
    Rs. 4.64/tablet
    Tablet
    Rs. 46.37
    save 9% more per tablet
  • MEXATE 2.5 MG TABLET
    (4 tablets in strip)
    Zydus Cadila
    Rs. 4.47/tablet
    Tablet
    Rs. 17.89
    save 13% more per tablet
  • FOLITRAX 25 MG TABLET
    (4 tablets in strip)
    Ipca Laboratories Ltd
    Rs. 39.88/tablet
    Tablet
    Rs. 159.50
    pay 679% more per tablet

Expert advice for NEOTREXATE

Do not take methotrexate:
  • If you are allergic (hypersensitive) to methotrexate or to any of the other ingredients of this medicines.
  • If you are pregnant, planning to become pregnant or are breastfeeding.
  • If you have severe kidney or liver problems such as fibrosis, cirrhosis and recent hepatitis.
  • If you are alcoholic.
Methotrexate should not be taken with food, as it may interact and reduce its absorption. Do not drive or use any tools or machines, if you feel dizzy, tired, have a headache or get blurred vision after taking methotrexate. Call your doctor if you have unusual bruising or bleeding, or signs of infection (fever, chills, body aches). Methotrexate is not recommended in children other than in cancer chemotherapy.Immediately consult  your doctor if you have upper stomach pain, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes), dry cough, shortness of breath, blood in your urine, or little or no urinating.Use birth control to prevent pregnancy while you are using methotrexate, whether you are a man or a woman. Methotrexate use by either parent may cause birth defects.Continue using condoms for at least 90 days after your treatment ends.Women should continue taking effective form of birth control for at least one cycle of ovulation after the treatment ends.

Frequently asked questions for NEOTREXATE

Methotrexate

Q.Is methotrexate a steroid/ chemotherapy/ disease-modifying antirheumatic drugs (DMARD)/ non-steroidal anti-inflammatory drugs (NSAIDs)?
Methotrexate is not a steroid or non-steroidal anti-inflammatory drugs (NSAIDs). It is a chemotherapy drug used in the treatment of different types of cancer and it is also a disease-modifying antirheumatic drugs (DMARD) used in the treatment of severe rheumatoid arthritis

Q.Is methotrexate safe for psoriasis?
Methotrexate belongs to a class of drugs known as antimetabolites used to treat severe, uncontrolled psoriasis. Methotrexate is safe if used at prescribed doses for the prescribed duration as advised by your doctor

Q.Is methotrexate cell cycle specific?
Yes. Methotrexate's chemotherapeutic effects are cell-cycle specific as it inhibits the DNA synthetic phase, i.e. it inhibits the synthesis of DNA (genetic material) of the cells. Hence in cancer treatment, it kills the cancerous cells and reduces the tumor size

Q.Is methotrexate safe/ How long can I take methotrexate for?
Methotrexate is safe if used at prescribed doses for the prescribed duration as advised by your doctor

Q.Is methotrexate a narcotic/ biologic drug?
No. Methotrexate is not a narcotic drug/ biologic drug

Q.Can I take methotrexate with antibiotics (e.g. amoxicillin, Bactrim)/ ibuprofen/ prednisone/ naproxen/ aspirin/ paracetamol?
No. Methotrexate interacts with antibiotics (e.g. amoxicillin, Bactrim), ibuprofen, prednisone, naproxen, aspirin, paracetamol. Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required

Q.Can I take methotrexate with a cold?
Always consult your doctor regarding its use if you have any symptoms of infection such as cold

Q.Does methotrexate cause cancer?
Methotrexate belongs to a class of drugs known as antimetabolites. It is used for the treatment of wide range of cancer and tumors. However it may increase the risk of secondary malignancies such as melanoma and other cancers

Q.Does methotrexate cause weight gain/ weight loss/ fatigue/ diarrhea/ acne/ mood swings/ nausea/ infertility?
Methotrexate may cause side effects such as fatigue, diarrhea, acne, mood swings, nausea, and infertility. But it has no known effect on weight gain/ weight loss

Q.Does methotrexate work and what does methotrexate treat?
Methotrexate belongs to a class of drugs known as antimetabolites. Methotrexate is used for the treatment of wide range of cancers or tumors including acute leukemias (a type of blood cancer), non-Hodgkin's lymphoma (a type of cancer of immune system cells that help the body fight infections), soft-tissue (fat, muscle, nerves, fibrous tissues, blood vessels, or deep skin tissues of the body) and osteogenic sarcomas (bone cancer), and solid tumors (cancers) of the breast, lung, head and neck, bladder, cervical, ovarian, choriocarcinoma and testicular carcinoma. It is also used to treat severe, uncontrolled psoriasis (skin condition where scaly patches were formed due to fast growing cells) and rheumatoid arthritis (inflammatory disorder that typically affects the small joints in hands and feet) only if these have not responded to other frontline treatments.

Top Medicines Prescribed with NEOTREXATE 2.5 MG TABLET

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Content on this page was last updated on 02 June, 2016, by Dr. Varun Gupta (MD Pharmacology)