Neomine 0.5mg Injection

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Neomine 0.5mg Injection is a prescription medicine used in the treatment of myasthenia gravis (a disease-causing muscle weakness and tiredness), paralytic ileus (paralysis of intestinal muscles), postoperative urinary retention, and for reversal of effect of skeletal muscle relaxants after surgery.

Neomine 0.5mg Injection works by reducing and improving muscle weakness. It is given as an injection under the supervision of a healthcare professional. Do not skip any doses and finish the full course of treatment and never stop this suddenly without talking to your doctor. However, before taking this medicine it is better to inform your doctor if you are suffering from any kidney disease, Parkinson's disease, asthma, or stomach disorders.

The most common side effects of this medicine are slow heart rate, nausea, and
vomiting. If you any other symptoms which you think are caused by the medicine, you should let your doctor know. They may be able to suggest ways to reduce or prevent the side effects.  Pregnant and breastfeeding women should consult the doctor before taking this medicine.

Uses of Neomine Injection

  • Treatment of Myasthenia gravis
  • Treatment of Paralytic ileus
  • Treatment of Post-operative urinary retention
  • Reversal of effect of skeletal muscle relaxant after surgery

Benefits of Neomine Injection

In Treatment of Myasthenia gravis

Myasthenia gravis is a neuromuscular disorder that leads to weakness of muscles that are under our control, such as those of the eyes, face, and swallowing. It can result in double vision, drooping eyelids, trouble talking, and trouble walking. It happens due to impaired coordination between muscles and nerves. Neomine 0.5mg Injection makes this coordination between nerves and muscles better and relieves the symptoms. As a result, your muscle strength is improved and you are able to lead a better life.

In Treatment of Paralytic ileus

Paralytic ileus is the obstruction of the intestines due to improper functioning of the nerves and muscles in the intestine that impairs digestive movement. Neomine 0.5mg Injection induces contractions in the intestinal muscles and improves their function. As a result, there is better movement of food and this treats the obstruction. Take it as advised by the doctor and follow your doctor’s instructions carefully.

In Treatment of Post-operative urinary retention

After an operation, there may be problems in emptying the bladder. This may be due to disturbed coordination of nerves and muscles of the bladder. Neomine 0.5mg Injection helps to improve this problem and treats postoperative urinary retention effectively.

In Reversal of effect of skeletal muscle relaxant after surgery

Skeletal muscle relaxants are given to induce anesthesia and to carry out surgical or certain diagnostic procedures. This blocks the conduction of signals between nerves and muscles. After the surgery, Neomine 0.5mg Injection is given to reverse this effect and cause muscle contraction again to restore normal function.

Side effects of Neomine Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Neomine

  • Nausea
  • Vomiting
  • Slow heart rate

How to use Neomine Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Neomine Injection works

Neomine 0.5mg Injection is a reversible cholinesterase inhibitor. It increases the level of acetylcholine, a chemical messenger in the brain, by suppressing acetylcholinesterase (enzyme). This acetylcholine further triggers muscle contracting receptors which helps in muscle contraction.

Safety advice

Neomine 0.5mg Injection may cause excessive drowsiness with alcohol.
Neomine 0.5mg Injection may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breast feeding
Neomine 0.5mg Injection is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
It is not known whether Neomine 0.5mg Injection alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react.
Neomine 0.5mg Injection should be used with caution in patients with kidney disease. Dose adjustment of Neomine 0.5mg Injection may be needed. Please consult your doctor.
Regular monitoring of kidney function test and some blood tests may advised while you are taking this medicine.
Neomine 0.5mg Injection is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of Neomine 0.5mg Injection may not be needed in these patients. Please consult your doctor.

What if you forget to take Neomine Injection?

If you miss a dose of Neomine 0.5mg Injection, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

Alternate brands

For informational purposes only. Consult a doctor before taking any medicines.
Neomine 0.5mg Injection
Tilstigmin 0.5mg Injection
Tablets India Limited
11% cheaper
Neotroy 0.5mg Injection
Troikaa Pharmaceuticals Ltd
173% costlier
Ostig 0.5mg Injection
Ciron Drugs & Pharmaceuticals Pvt Ltd
365% costlier
Myostigmin 0.5mg Injection 1ml
Neon Laboratories Ltd
495% costlier

Quick tips

  • It is given into veins, muscles or under the skin by a healthcare professional.
  • Do not drink alcohol while taking this medicine as it may worsen the side effects.
  • Inform your doctor if you have an existing kidney problem, parkinson's disease, asthma, or stomach disorders.

Fact Box

Chemical Class
Phenoxy Compounds
Habit Forming
Therapeutic Class
Action Class
Cholinesterase inhibitors- carbamates

Patient concerns

Drooping of eyelids. What is the cause of it? What is the remedy?
Dr. Vishal Maniar
At ur age u need detailed eye checkup and neurologist referenceTo rule out myasthenia gravis, ocular palsy Bells palsy,diabetes,trauma
Right medicine for myasthenia gravis
Dr. Vikas Sharma
many ; cant advise online as they are strong medicine
Do you have any questions related to Neomine 0.5mg Injection ?

User feedback


Q. Does Neomine 0.5mg Injection treat myasthenia gravis? How long do I need to take it?

Neomine 0.5mg Injection relieves the symptoms of myasthenia gravis but does not cure it. It does so by reducing and improving muscle weakness. The length of time for which you need to take Neomine 0.5mg Injection will depend on your condition. Do not stop taking Neomine 0.5mg Injection until and unless advised by your doctor, even if you start feeling better.

Q. How long does Neomine 0.5mg Injection take to start working?

Neomine 0.5mg Injection takes about 5 to 15 minutes to start working and remains effective for 2-4 hours.

Q. Is Neomine 0.5mg Injection a steroid?

No, Neomine 0.5mg Injection is not a steroid. It belongs to cholinesterase inhibitor group of medicines. Neomine 0.5mg Injection work by preventing the breakdown of a chemical called acetylcholine.

Q. Does it cause weight gain?

No, Neomine 0.5mg Injection does not cause weight gain. Your weight gain may be due to inactivity related to muscle weakness in myasthenia gravis.

Q. Is Neomine 0.5mg Injection safe to use?

Yes, Neomine 0.5mg Injection is safe if used in the dose and duration prescribed by the doctor.

Q. I felt better when I started taking Neomine 0.5mg Injection but I have noticed recently that I get tired easily and quickly. Will increasing the dose help me?

If your symptoms have started reappearing, then it could be due to increased severity of myasthenia gravis or excess dose of Neomine 0.5mg Injection. Both the conditions have similar effects, so it becomes very difficult to differentiate between the two. Do not increase the dose on your own and consult your doctor immediately.

Q. Can I take Neomine 0.5mg Injection for constipation?

No, Neomine 0.5mg Injection should not be taken for any type of constipation. However, its use is limited to cases of constipation caused by paralysis of intestine and strictly on prescription by the doctor.

Q. What should I do if I accidentally take more than the dose required?

You should seek immediate medical help in case of overdose of Neomine 0.5mg Injection.Excess of Neomine 0.5mg Injection may cause stomach pain, nausea, vomiting, diarrhea, blurred vision, difficulty in breathing, and excessive sweating, salivation, and weakness. It can even lead to paralysis.

Q. Does Neomine 0.5mg Injection have any abuse potential?

No, there is no evidence of Neomine 0.5mg Injection having any abuse potential.

Q. Who should not take Neomine 0.5mg Injection?

Neomine 0.5mg Injection should not be taken by patients who are allergic to it. Patients who are constipated or cannot urinate should avoid its use, unless advised by the doctor. This is because Neomine 0.5mg Injection is only used for certain types of urination problems and constipation (e.g. caused by paralysis of intestine).

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1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover all possible side effects, drug interactions or warnings or alerts. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.


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  5. Neostigmine Methylsulfate Injection [FDA Label]. Chesterfield, MO: Éclat Pharmaceuticals; 2013. [Accessed 24 Sept. 2020]. (online) Available from:External Link

Manufacturer/Marketer address

Zydus Tower, Satellite Cross Roads,Ahmedabad – 380015 Gujarat, India.
Inclusive of all taxes
1 ml in 1 vial


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