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MRP: Rs. 34.21 for 1 vial(s) (2 ML injection each)
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food interaction for NECOB PLUS

alcohol interaction for NECOB PLUS

pregnancy interaction for NECOB PLUS

lactation interaction for NECOB PLUS

Avoid Necob plus 1000mcg/100mg/100mg injection with acidic food and beverages such as sugar, certain dairy products, fish, processed foods, fresh meats and processed meats,sodas and other sweetened beverages.
Interaction with alcohol is unknown. Please consult your doctor.
Necob plus 1000mcg/100mg/100mg injection may be unsafe to use during pregnancy.
Either animal studies have shown adverse effect on fetus and there are no human studies or studies in human and animals are not available. It should be given only if potential benefits justifies risk to the fetus. Please consult your doctor.
Unknown. Human and animal studies are not available. Please consult your doctor.


Methylcobalamin(1000 mcg)


Methylcobalamin is an active form of vitamin B12, which is used to treat anemia as well as nerve damage with numbness, tingling, pain in various neurological disorders.

How it works

Methylcobalamin plays a key role in recovery process of damaged nerve cells and also it maintainins proper function of nerve cells.

Common side effects

Gastrointestinal disturbance, Allergic skin rash
Vitamin B6 (Pyridoxine)(100 mg)


It is used for the treatment and prevention of vitamin B6 deficiency. It is important for the breakdown of protein, fats, and carbohydrates from foods.

How it works

Vitamin B6, principally in its biologically active coenzyme form pyridoxal 5'-phosphate, is involved in a wide range of biochemical reactions, including the metabolism of amino acids and glycogen, the synthesis of nucleic acids, hemogloblin, sphingomyelin and other sphingolipids, and the synthesis of the neurotransmitters serotonin, dopamine, norepinephrine and gamma-aminobutyric acid (GABA).

Common side effects

Burning sensation, Tightness sensation, Headache, Nausea, Sleepiness, Stomach upset, Pricking sensation, Tingling sensation
Nicotinamide(100 mg)


Nicotinamide is used to treat vitamin B3 deficiency and inflammatory skin diseases like acne and pellagra.

How it works

Nicotinamide is an amide form of nicotinic acid. Nicotinamide is a component of two coenzymes, which help in tissue respiration and metabolism of  lipids, amino acids, proteins, and purines. Nicotinamide lowers blood cholesterol and triglyceride levels by inhibiting the synthesis of very low density lipoproteins.

Common side effects

Rash, Abnormal liver function tests, Allergic sensitization, Blurred vision, Diarrhoea, Dizziness, Flushing, Gastrointestinal discomfort, Vomiting, Nausea, Headache, Liver toxicity, Increased glucose level in blood


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Expert advice for NECOB PLUS

  • Do not take methylcobalmin if you are allergic (hypersensitive) to methylcobalamin, or any of the other ingredients of this medicine.
  • Tell your doctor if your occupation required you to handle mercury or its compound.
  • Do not use methylcobalamin over a period of months, if there is a lack of satisfactory clinical response.

Frequently asked questions for NECOB PLUS


Q. What is methylcobalamin/ mecobalamin/Neurokind/ Nurokind OD?
Methylcobalamin (mecobalamin/Neurokind/ Nurokind OD) is an active form of vitamin B12. It is water soluble and orally absorbed. It  is found in animal-based foods and in supplement form.

Q. Is methylcobalamin the same as cyanocobalamin?
No.Cyanocobalamin is different form of vitamin B12.

Q. What is Nurokind G, Nurokind plus, Nurokind Next, Nurokind LC, Nurokind Gold?
Nurokind G contains methylcobalmine and gabapentin. Nurokind plus contains methylcobalamin, folic acid, vitamin B1, vitamin B6 and alfa lipoic Acid. Nurokind Next contains methlcobalamin, alphalipoic acid, benfotiamine, pyridoxine hydrochloride, biotin, folic acid, chromium. NurokindL C contains L-carnitine, L-tartrate, methylcobalamin, folic acid. Nurokind Gold contains ginseng extract, mixed carotene 10%, niacinamide, vitamin B6, methylcobalamin, vitamin D3, refined wheat germ oil, folic acid, elemental calcium, elemental phosphorus, ferrous fumarate, zinc sulfate mono hydrate, elemental magnesium, elemental manganese, elemental copper, elemental iodine, elemental potassium.


Q. Is nicotinamide safe?
Nicotinamide is safe if used as recommended. In case of any side effects, consult your doctor.

Q. Does nicotinamide contain nicotine?
No. Nicotinamide in no way contain nicotine. Nicotinamide is amide form of nicotinic acid and used to treat skin diseases like acne and pellagra.

Q. Is nicotinamide good for acne?
Yes. Nicotinamide when taken along with zinc and folic acid is a good treatment of acne.

Q. Is nicotinamide the same as niacin?
No. Nicotinamide is an amide form of nicotinic acid.

Q. Is nicotinamide available over the counter?
Yes. Nicotinamide is available over the counter. However, please consult your doctor regarding its use.

Q. Does nicotinamide cause flushing?
In case of overdose, nicotinamide may cause flushing or rash. Always follow the instructions of doctor regarding the dosage and duration.


Content on this page was last updated on 26 January, 2014, by Dr. Varun Gupta (MD Pharmacology)