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NATFOST 500 MG INJECTION

Injection
MRP: Rs. 93.35 for 1 vial(s) (1 injection each)
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Composition for NATFOST

Amifostine(500 mg)

food interaction for NATFOST

alcohol interaction for NATFOST

pregnancy interaction for NATFOST

lactation interaction for NATFOST

food
alcohol
pregnancy
lactation
It can be taken with or without food, but it is better to take Natfost 500 mg injection at a fixed time.
Interaction with alcohol is unknown. Please consult your doctor.
Natfost 500 mg injection may be unsafe to use during pregnancy.
Animal studies have shown adverse effects on the foetus, however, there are limited human studies. The benefits from use in pregnant women may be acceptable despite the risk. Please consult your doctor.
WEIGH RISKS VS. BENEFITS
Natfost 500 mg injection is probably unsafe to use during breastfeeding. Please consult your doctor.
UNSAFE

SALT INFORMATION for NATFOST

Amifostine(500 mg)

Uses

Natfost 500 mg injection is used in the treatment of ovarian cancer, blood cancer, hemorrhagic cystitis and methotrexate toxicity.

How it works

Natfost 500 mg injection is a cytoprotectant. It protects the normal cells against the harmful effects of chemotherapy medications and radiation treatment by producing a chemical ‘thiol’ that binds to and detoxifies the harmful compounds produced by cisplatin. Natfost 500 mg injection does not interfere with the action of cisplatin.

Common side effects

Vomiting, Nausea, Chills, Shivering, Drowsiness, Fever, Flushing, Fatigue, Headache, Hiccup, Sneezing

SUBSTITUTES for NATFOST

4 Substitutes
Sorted By
RelevancePrice
  • CYTOFOS 500MG INJECTION
    (1 injection in vial)
    Sun Pharmaceutical Industries Ltd
    Rs. 1000/injection
    Injection
    Rs. 1000
    pay 971% more per injection
  • AMFOS 500MG INJECTION
    (1 injection in vial)
    Vhb Life Sciences Inc
    Rs. 1125/injection
    Injection
    Rs. 1125
    pay 1105% more per injection
  • AMIPHOS 500MG INJECTION
    (1 injection in vial)
    Dabur India Ltd
    Rs. 1910/injection
    Injection
    Rs. 1910
    pay 1946% more per injection
  • ETHYOL 500MG INJECTION
    (1 ML injection in vial)
    Fulford India Ltd
    Rs. 479/ML of injection
    generic_icon
    Rs. 479
    pay 413% more per ML of injection

Expert advice for NATFOST

  • Inform your doctor if you suffer from cardiovascular or cerebrovascular conditions such as ischemic heart disease (chest pain, discomfort or frank heart attack), arrhythmias (irregular heartbeats), heart failure, or have a history of stroke or transient ischemic attacks (mini stroke).
  • You need to be adequately hydrated prior to the amifostine infusion.
  • Frequent monitoring of blood pressure is required during infusion and use of antihypertensive drugs 24 hr prior to start of amifostine infusion should be avoided.
  • Tell your doctor if you are or planning to become pregnant or are breastfeeding.
  • Inform your doctor immediately if you develop any skin reaction or reactions in and around the mouth, any time following amifostine administration. 
  • Amifostine is not recommended for use in elderly.

Frequently asked questions for NATFOST

Amifostine

Q.Is amifostine FDA approved?
Yes, it is FDA an approved drug

Q.What is amifostine used for?
Amifostine is used to reduce toxicity to kidneys associated with cisplatin therapy in patients with advanced ovarian cancer, and in prevention of dry mouth (xerostomia) during radiotherapy for head and neck cancer

Q.How does amifostine work?
It protects the normal cells against the harmful effects of chemotherapy medications and radiation treatment by producing a chemical ‘thiol' that binds to and detoxifies the harmful compounds produced by cisplatin. Amifostine does not interfere with the action of cisplatin.

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Content on this page was last updated on 10 April, 2014, by Dr. Varun Gupta (MD Pharmacology)