Motivyst 300mg Tablet

Johnson & Johnson Ltd

Composition for Motivyst 300mg Tablet

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Primarily used for

10 tablets in 1 strip

Medicine Overview of Motivyst Tablet


Uses of Motivyst Tablet

Motivyst 300mg Tablet is used in the treatment of type 2 diabetes.

Side effects of Motivyst Tablet


Nausea, Frequent urge to urinate, Increased thirst, Urinary tract infection, Hypoglycaemia (low blood sugar level) in combination with insulin or sulphonylurea, Genital fungal infection.


How to use Motivyst Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. It is better to take Motivyst 300mg Tablet empty stomach (1 hour before food or 2 hours after food).

How Motivyst Tablet works

Motivyst 300mg tablet is a sodium-glucose co-transporter 2 (SGLT2) inhibitors. It works in type 2 diabetes by increasing the amount of glucose that gets passed out in the urine.

In Depth Information on Motivyst Tablet

Expert advice for Motivyst Tablet

  • Can cause very low blood sugar levels when used with other antidiabetic medicines, alcohol or if you delay or miss a meal. Get blood sugar levels checked at regular intervals and always keep a source of sugar with you for quick relief.
  • It can cause dehydration (the loss of too much body water) which may cause you to feel dizzy, faint, lightheaded, or weak, especially when you stand up (orthostatic hypotension).
  • Motivyst may cause fungal infections of the vagina. Inform your doctor if you get the vaginal odour, white or yellowish vaginal discharge or vaginal itching.
  • Motivyst may cause a fungal infection of the penis. Inform your doctor if you get redness, itching, or swelling of the penis; rash on the penis; foul-smelling discharge from the penis; or pain in the skin around the penis.
  • Motivyst may cause urinary tract infection. Inform your doctor if you get burning sensation when passing urine, pain in the pelvis, or mid back pain, or increased need to urinate.
  • Inform your doctor if you have ever been diagnosed with the kidney disease. Your dose may need to be adjusted.
  • Inform your doctor if you are pregnant or planning to conceive or breastfeeding.
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Special precautions for Motivyst 300mg Tablet
Taking canagliflozin with alcohol may affect blood glucose levels in patients with diabetes.
Motivyst 300mg Tablet may be unsafe to use during pregnancy.

Animal studies have shown adverse effects on the foetus, however, there are limited human studies. The benefits from use in pregnant women may be acceptable despite the risk. Please consult your doctor.
No information is available on the use of Motivyst 300mg Tab
let during lactation. Please consult your doctor.
Motivyst 300mg Tablet may make you feel dizzy, sleepy, tired
, or decrease alertness. If this happens, do not drive.
Motivyst 300mg Tablet is probably unsafe to use in patients
with kidney disease and should be avoided. Please consult your doctor.
Motivyst 300mg Tablet should be used with caution in patients with severe liver disease. Dose adjustment of Motivyst 300mg Tablet may be needed. Please consult your doctor.

Dose adjustment is not needed in patients with mild to moderate liver disease. Limited information is available on use of Motivyst 300mg Tablet in severe liver disease.
Severely interacts with other drugs like
Decamycin 4mg Injection, Walacort 0.5mg Tablet, Pericort 4mg Tablet, Depo Medrol 40mg Injection

Missed Dosageuses

If you miss a dose of Canagliflozin, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

Patient Concerns

Frequently asked questions for Motivyst 300mg Tablet

Frequently asked questions for Canagliflozin

Q. What makes Motivyst better than glimepiride?
Both are effective in lowering blood glucose levels, however, they work in different ways and have different side effect profile. Glimepiride commonly causes hypoglycemia and weight gain while Motivyst causes hypoglycemia when taken with insulins or sulfonylureas and helps in loosing weight. Motivyst commonly causes urinary tract and genital infections.
Q. How is Motivyst different from dapagliflozin?
Both belong to the same class drugs and work by removing glucose from urine. However, Motivyst is more effective in removing a higher amount of glucose through urine in 24 hours than dapagliflozin. Also, the use of dapagliflozin is to be avoided in patients with bladder cancer.
Q. Is Motivyst better than sitagliptin for the control of my blood sugar?
Both Motivyst and sitagliptin lower blood sugar levels but work in different ways. Motivyst removes glucose from the body through urine while sitagliptin increases the release of insulin which lowers blood glucose levels. Motivyst causes urinary and genital tract infection while sitagliptin causes nausea and increases the risk of pancreatitis. Motivyst may cause weight loss while sitagliptin does not show any effect on weight.
Q. What is the benefit of using Motivyst with metformin?
The combination of Motivyst and metformin helps in a significant improvement of blood glucose levels and glycosylated hemoglobin as compared to when they are taken alone.
Motivyst is seen to increase low-density lipoprotein (LDL) levels in some patients. Get LDL levels checked regularly. However, the increase is not seen to be clinically significant and Motivyst can also increase the triglyceride (TG) and high-density lipoprotein levels (HDL). However, the exact mechanism for this effect is not known but is related to urinary glucose excretion.
Motivyst along with well-balanced diet and exercise works effectively in lowering blood glucose levels and weight loss in type 2 diabetes patients. Motivyst works by removing glucose through urine, so, calories are lost resulting in weight loss according to some clinical studies.
Do not stop taking Motivyst immediately or over a period of time without consulting your doctor as the change in your treatment would depend on your blood glucose levels and other associated side effects or complications if any.
Motivyst can increase the risk of leg and foot amputation. Inform your doctor if you have a history of diabetic foot ulcer, peripheral vascular disease, neuropathy or amputation. In case you notice tenderness, pain, numbness, tingling sensation, discoloration, sores or ulcers in the lower limb if you are taking Motivyst, immediately contact your doctor.
Motivyst starts to show its effect from the first dose itself but the complete effect is noticed after 1 week of starting the medicine.
Motivyst is not advised in patients with type 1 Diabetes, severe liver or kidney disease or on dialysis, diabetic ketoacidosis (elevated blood or urine ketone levels), patients planning for pregnancy or pregnant or nursing mother, patients with a history of allergy to this medicine, have low or high blood pressure or high cholesterol levels.
Q. Is Motivyst better than metformin?
Yes, Motivyst can be taken with metformin. A combined use of the two medicines can significantly improve blood glucose levels and glycosylated hemoglobin (HbA1c) and help in weight loss as compared to when either of the medicine is taken alone. No change in side effect profile has been reported compared to when they are used alone.
Motivyst is not indicated for use in patients with type 1 diabetes mellitus as these patients tend to pass more urine. Motivyst works by removing glucose through the urine and also increases the urine frequency. So, a combined effect may worsen dehydration. There have been reports of diabetic ketoacidosis with Motivyst, a complication seen in type 1 diabetic patients and which may also get worsened in these patients.
Motivyst can be used as an add-on to insulin. However, it is known to cause hypoglycemia (low blood glucose levels) when used with insulin or sulfonylurea group of anti-diabetics. So, a regular monitoring of blood sugar is important when they are used together.
Q. How is Motivyst different from liraglutide?
Both are anti-diabetic medicines and lower blood glucose levels effectively and can cause weight loss. Motivyst is to be taken by mouth and works by removing glucose from the body through urine and can cause urinary and genital tract infection. While liraglutide is an injectable which increases the release of insulin which lowers blood glucose levels and commonly causes nausea and increases the risk of pancreatitis.
Motivyst can cause low blood sugar level (hypoglycemia) but this is not very common. However, the risk of hypoglycemia may increase significantly when used along with insulins and sulfonylureas especially in patients with underlying chronic kidney disease and in elderly patients.
Motivyst lowers blood glucose levels by removing glucose through urine and patient passes increased amount of urine which may lead to dehydration and increase potassium levels in the blood (hyperkalemia). It is more common in patients with chronic kidney disease and elderly patients.
Motivyst is known to cause a small increase in low-density lipoprotein (LDL). However, the exact mechanism for this effect is not known.

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