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Composition FOR MIREL

Reteplase(18 mg)

food interaction for MIREL

alcohol interaction for MIREL

pregnancy interaction for MIREL

lactation interaction for MIREL

It can be taken with or without food, but it is better to take Mirel 18mg kit at a fixed time.
Interaction with alcohol is unknown. Please consult your doctor.
Mirel 18mg kit may be unsafe to use during pregnancy.
Animal studies have shown adverse effects on the foetus, however, there are limited human studies. The benefits from use in pregnant women may be acceptable despite the risk. Please consult your doctor.
Unknown. Human and animal studies are not available. Please consult your doctor.


Reteplase(18 mg)


Mirel 18mg kit is used for heart attack, pulmonary embolus (blood clot in lungs) and ischemic stroke (decreased blood supply to brain)

How it works

Mirel 18mg kit belongs to class of medicines called thrombolytics. It works by dissolving the blood clots (splitting of endogenous plasminogen to plasmin), thereby preventing heart failure and death in patients who previously had heart attack.

Common side effects

Abnormal heart rhythm, Dizziness, Muscle pain, Cerebral hemorrhage, Allergic reaction, Injection site inflammation, Slow growth in children and teenagers, Cardiac adverse reaction, Altered cholesterol level, Hormone imbalance, Fever, Anemia, Chills, Bleeding, Nose bleed, Gastrointestinal bleeding, Decreased blood pressure


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Expert advice FOR MIREL

  • Consult your doctor if you are suffering from any of the following: cerebrovascular disease, high blood pressure, gastrointestinal or genitourinary bleeding within 10 days, narrowing of the valves on the left side of the heart (mitral stenosis) with fast uncontrolled heartbeat (atrial fibrillation), inflammation of a vein caused by a blood clot (septic thrombophlebitis) or occluded arteriovenous cannula at seriously infected site.
  • You will be carefully evaluated for bleeding risk during treatment with reteplase.
  • Seek immediate medical advice if you feel palpitations or an irregular heartbeat after the administration of reteplase.
  • Take necessary precautions if your age is over 75 years as you are at high risk of bleeding.
  • Do not take reteplase along with heparin.
  • Stop taking reteplase and seek immediate medical attention if you develop severe allergic reaction.
  • Use of reteplase is not recommended in children.
  • Tell your doctor if you are or planning to become pregnant or are breastfeeding.

Frequently asked questions FOR MIREL



What is reteplase drug class?
Reteplase belongs to class of medicines called thrombolytics


What is reteplase used for?
Reteplase is used to improve heart function and prevent congestive heart failure or death in people who have had a heart attack


How does reteplase work?
Reteplase works by dissolving the blood clots (splitting of endogenous plasminogen to plasmin).


Content on this page was last updated on 03 February, 2017, by Dr. Varun Gupta (MD Pharmacology)