MEXT F 7.5MG/1MG TABLET

Tablet
Rs.60for 1 strip(s) (28 tablets each)
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Composition FOR MEXT F

Methotrexate(7.5mg),Folic Acid(1mg)

food interaction for MEXT F

alcohol interaction for MEXT F

pregnancy interaction for MEXT F

lactation interaction for MEXT F

food
alcohol
pregnancy
lactation
There is no data available. Please consult doctor before consuming the drug.
Mext f 7.5mg/1mg tablet may cause symptoms such as flushing, increased heartbeat, nausea, thirst, chest pain and low blood pressure with alcohol (Disulfiram reactions).
Taking Methotrxate with alcohol increases the risk of liver damage.
UNSAFE
Mext f 7.5mg/1mg tablet is highly unsafe to use during pregnancy.
Human and animal studies have shown significant adverse effects on the foetus. Please consult your doctor.
UNSAFE
Mext f 7.5mg/1mg tablet is probably unsafe to use during breastfeeding. Please consult your doctor.
UNSAFE

SALT INFORMATION FOR MEXT F

Methotrexate(7.5mg)

Uses

Methotrexate is used in the treatment of blood cancer, bone cancer, non-hodgkin lymphoma (nhl), breast cancer, lung cancer, head and neck cancer, cervical cancer, ovarian cancer and testicular cancer.
It is also used in rheumatoid arthritis, psoriasis (silvery scaly skin rash) and ectopic pregnancy at low doses.

How it works

Methotrexate works in cancer by slowing the growth of cancer cells by blocking building blocks that cancer cells need to grow. It works in autoimmune disease by decreasing the activity of body's immune system and prevents the body from attacking itself.

Common side effects

Nausea, Vomiting, Loss of appetite, Dyspepsia, Abdominal pain, Increased liver enzymes, Stomatitis (Inflammation of the mouth).
Folic Acid(1mg)

Uses

Folic Acid is used in the treatment of iron deficiency anemia and anemia due to chronic kidney disease.

How it works

Folic acid is a component of the B group of vitamins and is necessary for the normal production and maturation of red blood cells.
.

Common side effects

Nausea, Abdominal distension, Decreased appetite, Flatulence.

COMMON DOSAGE FOR MEXT F 7.5MG/1MG TABLET

Patients taking MEXT F 7.5MG/1MG TABLET

  • 87%
    Once A Day
  • 13%
    Once A Week

SUBSTITUTES FOR MEXT F

1 Substitutes
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Expert advice FOR MEXT F

  • For autoimmune diseases, Methotrexate is taken by mouth, once a week (not every day) on the same day each week. It can take 2 to 3 weeks for Methotrexate to start working.
  • Notify your doctor immediately if you develop a sore throat or fever (infection), bruising or bleeding, nausea, abdominal pain or dark urine or difficulty breathing.
  • Your doctor may ask to get complete blood count (CBC), kidney function test (KFT) and liver function test (LFT) before starting treatment and thereafter also.
  • Methotrexate may harm your unborn babies or cause miscarriages. You and your partner should avoid conception (becoming pregnant or fathering children) for at least three months after your treatment with Methotrexate has stopped.
  • Inform your doctor if you are pregnant or planning to conceive or breastfeeding.
  • Inform your doctor if you have ever been diagnosed with kidney or liver problems.

Frequently asked questions FOR MEXT F

Methotrexate

Q. Is methotrexate a steroid/ chemotherapy/ disease-modifying antirheumatic drugs (DMARD)/ non-steroidal anti-inflammatory drugs (NSAIDs)?
Methotrexate is not a steroid or non-steroidal anti-inflammatory drugs (NSAIDs). It is a chemotherapy drug used in the treatment of different types of cancer and it is also a disease-modifying antirheumatic drugs (DMARD) used in the treatment of severe rheumatoid arthritis
Q. Is methotrexate safe for psoriasis?
Methotrexate belongs to a class of drugs known as antimetabolites used to treat severe, uncontrolled psoriasis. Methotrexate is safe if used at prescribed doses for the prescribed duration as advised by your doctor
Q. Is methotrexate cell cycle specific?
Yes. Methotrexate's chemotherapeutic effects are cell-cycle specific as it inhibits the DNA synthetic phase, i.e. it inhibits the synthesis of DNA (genetic material) of the cells. Hence in cancer treatment, it kills the cancerous cells and reduces the tumor size
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Q. Is methotrexate safe/ How long can I take methotrexate for?
Methotrexate is safe if used at prescribed doses for the prescribed duration as advised by your doctor
Q. Is methotrexate a narcotic/ biologic drug?
No. Methotrexate is not a narcotic drug/ biologic drug
Q. Can I take methotrexate with antibiotics (e.g. amoxicillin, Bactrim)/ ibuprofen/ prednisone/ naproxen/ aspirin/ paracetamol?
No. Methotrexate interacts with antibiotics (e.g. amoxicillin, Bactrim), ibuprofen, prednisone, naproxen, aspirin, paracetamol. Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required
Q. Can I take methotrexate with a cold?
Always consult your doctor regarding its use if you have any symptoms of infection such as cold
Q. Does methotrexate cause cancer?
Methotrexate belongs to a class of drugs known as antimetabolites. It is used for the treatment of wide range of cancer and tumors. However it may increase the risk of secondary malignancies such as melanoma and other cancers
Q. Does methotrexate cause weight gain/ weight loss/ fatigue/ diarrhea/ acne/ mood swings/ nausea/ infertility?
Methotrexate may cause side effects such as fatigue, diarrhea, acne, mood swings, nausea, and infertility. But it has no known effect on weight gain/ weight loss
Q. Does methotrexate work and what does methotrexate treat?
Methotrexate belongs to a class of drugs known as antimetabolites. Methotrexate is used for the treatment of wide range of cancers or tumors including acute leukemias (a type of blood cancer), non-Hodgkin's lymphoma (a type of cancer of immune system cells that help the body fight infections), soft-tissue (fat, muscle, nerves, fibrous tissues, blood vessels, or deep skin tissues of the body) and osteogenic sarcomas (bone cancer), and solid tumors (cancers) of the breast, lung, head and neck, bladder, cervical, ovarian, choriocarcinoma and testicular carcinoma. It is also used to treat severe, uncontrolled psoriasis (skin condition where scaly patches were formed due to fast growing cells) and rheumatoid arthritis (inflammatory disorder that typically affects the small joints in hands and feet) only if these have not responded to other frontline treatments.

Folic Acid

Q. Does folic acid contain iron?
Folic acid is a component of the B group of vitamins
Q. Can I take folic acid with iron supplement?
It does not contain iron and can be taken with iron supplement
Q. Does vitamin D have folic acid?
Folic acid is a component of the B group of vitamins and it does not have Vitamin D
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Q. Is folic acid good for everyone/skin/health/polycystic ovarian syndrome (PCOS)/hair loss/anemia?
Everyone needs folic acid for good health. It is good for skin, hair, polycystic ovarian syndrome (PCOS) and anemia. However, patients should follow the advice of the doctor regarding the use of folic acid
Q. What is Folvite/ Fol123/ Folvite MB tablet used for?
Folvite/ Fol123/ Folvite MB are the trade names for active drug folic acid. Folvite contains only folic acid which is a component of the B group of vitamins. While Fol123/ Folvite MB, in addition to folic acid also has other forms of vitamin B. In addition folic acid is also used for prevention of folate deficiency caused by some medicines (e.g. phenytoin, phenobarbital and primidone used to treat epilepsy), folate deficiency caused by long-term red blood cell damage or kidney dialysis However, patients should follow the advice of the doctor regarding the dose and duration of use of folic acid
Q. How long can I take folic acid for?
Always follow the instructions of doctor regarding the dosage and duration
Q. Does folic acid have side effects increase weight/acidity?
Folic acid may have rare side effect like acidity, while it has no known effect on weight gain
Q. Can I take folic acid with birth control?
Folic acid supplementation does not affect birth control, and can be taken if you are suffering from anemia due to folic acid deficiency However, always follow the advice of the doctor regarding the dose and duration of use of folic acid
Q. Can I take folic acid with methotrexate/warfarin/calcium/metformin/antibiotics?
Folic acid may interact with medicines such as methotrexate/sulfonamide antibiotics (sulfasalazine, cotrimoxazole etc). It has no known effect if taken with warfarin/calcium/ metformin.

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Content on this page was last updated on 08 March, 2017, by Dr. Varun Gupta (MD Pharmacology)