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Mext 50mg Injection


Overview

Introduction

Mext 50mg Injection is a medicine used for treatment of cancer in various parts of the body such as breasts, head, neck, lungs, blood, bone, lymph, and uterus. It may be used with other medicines as part of combination therapy.

Mext 50mg Injection is given under the supervision of a healthcare professional and should not be self-administered. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to. You should avoid drinking alcohol as it may increase your risk of liver damage.

The most common side effects of this medicine include nausea, vomiting, loss of appetite, abdominal pain, tiredness, and mouth sores. Your doctor may advise you to take folic acid to reduce some of these. If they do not go away or get worse, tell your doctor. There may be ways of preventing or reducing these effects. It is a very strong medicine and some people may develop serious side effects while taking it. This medicine may lower your ability to fight infections and lead to problems with your blood, liver or kidneys. Your doctor will advise you regular blood tests to check for these.

Before taking it, tell your doctor if have stomach, liver, or kidney problems or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your healthcare team know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. It may harm your baby. You and your partner should avoid becoming pregnant or fathering a child for several months after your treatment with it has stopped. Your doctor may perform several tests such as blood tests, X-rays and physical examinations both before and during treatment with this medicine.

Uses of Mext Injection

Side effects of Mext Injection

Common
  • Nausea
  • Vomiting
  • Loss of appetite
  • Dyspepsia
  • Abdominal pain
  • Increased liver enzymes
  • Stomatitis (Inflammation of the mouth)

How to use Mext Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Mext Injection works

Mext 50mg Injection is an anti-cancer medication. It works by blocking an enzyme (dihydrofolate reductase) involved in DNA synthesis in cancer cells. This slows the growth of cancer cells and eventually kills them.

Safety Advice

Alcohol
CAUTION
Caution is advised when consuming alcohol with Mext 50mg Injection. Please consult your doctor.
Pregnancy
UNSAFE
Mext 50mg Injection is highly unsafe to use during pregnancy. Seek your doctor's advice as studies on pregnant women and animals have shown significant harmful effects to the developing baby.
Breastfeeding
UNSAFE
Mext 50mg Injection is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
Driving
UNSAFE
Mext 50mg Injection may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Kidney
CAUTION
Mext 50mg Injection should be used with caution in patients with kidney disease. Dose adjustment of Mext 50mg Injection may be needed. Please consult your doctor.
Regular monitoring of kidney function test is advised while you are taking this medicine.
Liver
CAUTION
Mext 50mg Injection should be used with caution in patients with liver disease. Dose adjustment of Mext 50mg Injection may be needed. Please consult your doctor.
Use of Mext 50mg Injection is not recommended in patients with severe liver disease.

Alternate Brands

For informational purposes only. Consult a doctor before taking any medicines.
Mext 50mg Injection
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Quick Tips

  • Mext 50mg Injection helps treat various types of cancer such as blood cancer, bone cancer, non-Hodgkin lymphoma (NHL), breast cancer, lung cancer, head and neck cancer, cervical cancer, ovarian cancer and testicular cancer.
  • Take it once a week, on the same day every week.
  • Drink plenty of liquids to stay hydrated while taking this  medication.
  • Always take folic acid as advised by your doctor. This will help lessen the side effects of this medicine.
  • It may take 6 to 8 weeks for Mext 50mg Injection to work. Keep taking the medication as prescribed.
  • Avoid drinking alcohol while taking this medicine as it may increase the risk of side effects.
  • It can be harmful to an unborn baby. Avoid pregnancy for at least 6 months after your last dose.
  • Your doctor may get regular blood test done to monitor your kidney function, liver function and level of blood cells in your blood.

Interaction with Drugs

Taking Mext with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Brand(s): Rotasiil, Rotarix, RotaTeq
LIFE-THREATENING
LIFE-THREATENING
Brand(s): Abhay M, Measles, M-Vac
LIFE-THREATENING
Brand(s): Rubella
LIFE-THREATENING

Patient Concerns

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Patient is sufferng from Prostrate cancer and now he is suffering from Typhoid IGM.His hormone therapy(Inj Leuprolide 3.75 mg) is due for can we go ahead and ask doctor to induct hormone injection.
Dr. Vijay Sharnangat
Cancer Specialist
If patient has recovered, then only.
Submucouse fibrosis and unable to open mouth
Dr. Shubhra Chandan Pradhan
Ear Nose Throat Specialist
It is usually due to chronic tobacco chewing. If you are taking stop. Takes long time to improve. May become cancer later on. Can use hyalase and kenacort injection locally. Improve in few patients. It it very severe may need surgery
arrow
Do you have any questions related to Mext 50mg Injection ?

FAQs

Q. Can Mext cause mouth ulcers?

Yes, in fact a sore mouth and mouth ulcers are sometimes side effects of Mext therapy. Taking folic acid along with this medicine may help in reducing the ulcers. Ask your doctor if the dose can be reduced as dose reduction may further help in reducing the ulcers.

Q. Why do I have to take folic acid with Mext?

Folic acid is required to make new cells in the body and Mext decreases the folic acid levels in the body. By taking folic acid some of the common side effects, like mouth ulcers, hair loss, nausea, heartburn, abdominal pain, fatigue, anemia and liver problems can be reduced.

Q. Why do I need to take regular blood tests while taking Mext?

Regular blood tests will help your doctor to check your response to Mext and monitor you for side effects. You will need to regularly check your liver function and your blood counts -white blood cells, red blood cells and platelets. Your doctor may also order additional tests depending on the results.

Q. Can Mext use make me more prone to infections?

Mext may decrease the activity of your immune system. As a result, you may develop serious infections. There have been rare reports of serious lung infections with Mext use. If you have an active infection, Mext should be used with extreme caution.

Q. Can Mext affect fertility?

Yes, it may affect fertility in both males and females. There may be a decrease in sperm count in males and menstrual disturbances in females. These effects are reversible and disappear once the therapy is discontinued.

Q. What to do if I am planning to become pregnant and my husband is taking Mext?

You should avoid pregnancy if your husband is taking Mext. Also, avoid pregnancy for a minimum of 3 months after the therapy as it can lead to serious fetal abnormalities.

Related Products

Disclaimer: 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover all possible side effects, drug interactions or warnings or alerts. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.
References
  1. Chu E, Sartorelli AC. Cancer Chemotherapy. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 944-46.
  2. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 887-90.
  3. Drugs.com. Methotrexate Pregnancy and Breastfeeding Warnings. [Accessed 02 Apr. 2019] (online) Available from:External Link
Manufacturer/Marketer Address
Wallace Pharmaceuticals Pvt. Ltd., 3rd Floor, Dempo Trade Centre Bldg., Patto Plaza, EDC Complex, Panaji 403001, Goa, India.
A licensed pharmacy from your nearest location will deliver Mext 50mg Injection. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your prescription and the availability of this medicine.
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1 Injection in 1 vial
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