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MRP: Rs. 91.60 for 1 packet(s) (5 suppositorys each)
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Composition for MESACOL

Mesalazine Topical(500mg)

food interaction for MESACOL

alcohol interaction for MESACOL

pregnancy interaction for MESACOL

lactation interaction for MESACOL

It is better to take Mesacol 500mg suppository with food.
Interaction with alcohol is unknown. Please consult your doctor.
Mesacol 500mg suppository is probably safe to use during pregnancy.
Either animal studies have shown no adverse effect on the fetus, but there is no human studies or animal studies have shown an adverse effect that was not confirmed in human studies. Please consult your doctor.
Mesacol 500mg suppository is probably safe to use during breastfeeding. Please consult your doctor.


Mesalazine Topical(500mg)


Mesalazine also known as mesalamine, is topically used for the treatment and prevention of short episodes of ulcerative colitis (inflammatory disease of colon), Crohn’s ileocolitis (inflammation of lining of ileum and colon), proctosigmoiditis or proctitis (disease confined to rectum or lower intestine). It is also used to reduce bleeding, mucous and bloody diarrhea caused by inflammation (swelling and soreness) of the rectal area.

How it works

Mesalazine belongs to the class of medications called as salicylates. It acts locally on the intestinal lining to reduce the inflammation and prevents further swelling, ulcers or abscess (puss filled swelling) thereby relieving associated symptoms.

Common side effects

Vomiting, Nausea, Abdominal bloating, Abdominal pain, Diarrhoea, Headache, Rash, Itching, Rectal pain, Stomach pain


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Expert advice for MESACOL

  • The enema should be used in the back passage (rectum) only.
  • Consult your doctor and discontinue use if you experience any unexplained bleeding, bruising, skin rashes, fever or sore throat, chest pain, an increased heartbeat and excess tiredness.
  • Inform your doctor if you get fever, severe itching or a rash or headache.
  • Tell your doctor if you are pregnant, planning to become pregnant or are breastfeeding.
  • Do not use if you are allergic to mesalazine or any of its ingredients.
  • Do not use if you have severe liver or kidney dysfunction. 
  • Do not use by Children.

Frequently asked questions for MESACOL

Mesalazine Topical

Q. Is mesalazine a steroid, NSAID, immunosuppressant, blood-thinner or sulfa drug?
Mesalazine is not a steroid, NSAID, immunosuppressant, blood-thinner or sulfa drug. It is an anti-inflammatory drug.
Q. Is mesalazine topical safe?
Yes. Mesalazine topical is relatively safe if used as recommended. In case of any side-effects, consult your doctor.


Content on this page was last updated on 03 June, 2016, by Dr. Varun Gupta (MD Pharmacology)