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MRP: Rs. 589 for 1 vial(s) (1 ML injection each)
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Composition for MEPRESSO

Methylprednisolone(500 mg)

food interaction for MEPRESSO

alcohol interaction for MEPRESSO

pregnancy interaction for MEPRESSO

lactation interaction for MEPRESSO

It is better to take Mepresso 500 mg injection with food.
Interaction with alcohol is unknown. Please consult your doctor.
Mepresso 500 mg injection may be unsafe to use during pregnancy.
Either animal studies have shown adverse effect on fetus and there are no human studies or studies in human and animals are not available. It should be given only if potential benefits justifies risk to the fetus. Please consult your doctor.
Unknown. Human and animal studies are not available. Please consult your doctor.


Methylprednisolone(500 mg)


Mepresso 500 mg injection is used to treat inflammation and allergies associated with various diseases of skin (dermatitis), brain (meningitis), gastro-intestinal tract (Crohn’s disease), blood (leukemia), bones (arthritis), lungs (asthma, tuberculosis) and muscles (dermatomyositis, polymyositis). It is also used to support organ transplant.

How it works

Mepresso 500 mg injection belongs to a group of medicines called as corticosteroids. It increases the level of corticosteroid, which are naturally present in the body and thereby controls inflammation. It has anti-inflammatory, metabolic, immune, and hormonal effects on the body.

Common side effects

Abnormal vision, Acne, Facial swelling, Allergic reaction, Difficulty in swallowing, Anxiety, Central nervous system depression, Cold, Dizziness, Easy bruise, Headache, Increased hair growth, Insomnia, Absence of menstrual periods, Irregular menstrual cycle, Black and bloody stools, Muscle weakness, Restlessness, Skin rash, Stomach irritation, Stomach upset, Vomiting


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Expert advice for MEPRESSO

Do not take the medicine:
  • If you are allergic to it or to any other content in the medicine.
  • If you have a serious infection, particularly in the lungs or esophagus, that is untreated. 
Do not stop this medicine before recommended duration. Consult your doctor for gradual reduction of dose.Do not receive a "live" vaccine while using methylprednisolone. The vaccine may not work as well during this time, and may not fully protect you from disease.Inform your doctor before taking the medicine:
  • If you are suffering from any infection.
  • If you are pregnant or planning to become pregnant or breast-feeding a baby.
Inform your doctor before taking the medicine:
  • If you are taking antibiotics for any infection, pain killers or contraceptive pills or any medication for heart disease or peptic ulcer.
  • If you are going to undergo any laboratory test.
Stay away from people who are suffering from infections like chicken-pox, measles, shingles or tuberculosis.

Frequently asked questions for MEPRESSO


Q. Is methylprednisolone a steroid oral antibiotic drug?
Methylprednisolone is a corticosteroid/steroid drug. It is not an antibiotic.
Q. Is methylprednisolone a narcotic or addictive drug?
No. Methylprednisolone is not a narcotic or an addictive drug.
Q. Is methylprednisolone the same as prednisone, prednisolone, or dexamethasone?
No. Methylprednisolone, prednisolone, prednisone and dexamethasone are different steroid drugs belonging to the same class.
Q. Can I take methylprednisolone for strep throat, sinus infection, bronchitis, or poison ivy?
Methylprednisolone may be effective in skin allergy due to poison ivy. But it should not be taken for suspected bacterial or viral infection including strep throat, sinus infection or bronchitis.
Q. Can I take methylprednisolone with ibuprofen, Nyquil, Benadryl, amoxicillin, Vicodin, or Synthroid?
Yes, methylprednisolone can be taken with ibuprofen, Nyquil, Benadryl, amoxicillin, Vicodin, or Synthroid (levothyroxine) only if prescribed by your doctor.
Q. Can I take methylprednisolone if I have high blood pressure?
You can take methylprednisolone if you have high blood pressure, only when prescribed by your doctor. It is prescribed in such situation when benefit outweighs the risk.
Q. Does methylprednisolone cause insomnia, constipation, heartburn, weight loss, hair loss, or sweating?
Yes. Methylprednisolone may cause insomnia, constipation, heartburn, sweating or hair loss. It usually causes weight gain, not weight loss. If you experience any such symptoms, please contact your doctor.
Q. Does methylprednisolone affect birth control?
Methylprednisolone may affect the protection by oral contraceptive pill. Please consult your doctor to confirm whether you require a secondary birth control measure while taking methylprednisolone.


Content on this page was last updated on 10 January, 2016, by Dr. Varun Gupta (MD Pharmacology)