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MRP: Rs. 190 for 1 vial(s) (2 ML injection each)
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Composition for MALOCIDE

Pyrimethamine(60 mg),Sulphadoxine(NA)

food interaction for MALOCIDE

alcohol interaction for MALOCIDE

pregnancy interaction for MALOCIDE

lactation interaction for MALOCIDE

There is no data available. Please consult doctor before consuming the drug.
Interaction with alcohol is unknown. Please consult your doctor.
Malocide injection may be unsafe to use during pregnancy.
Either animal studies have shown adverse effect on fetus and there are no human studies or studies in human and animals are not available. It should be given only if potential benefits justifies risk to the fetus. Please consult your doctor.
Unknown. Human and animal studies are not available. Please consult your doctor.


Pyrimethamine(60 mg)


Pyrimethamine along with other antibiotic sulphonamides is used to treat toxoplasmosis, an infection caused by the Toxoplasma parasite. It is also used to treat or prevent malaria infections along with other medicine.

How it works

Pyrimethamine belongs to a group of medicines called antiprotozoals. It is an antiparasitic and works by killing the parasites or preventing their growth in the blood stream.

Common side effects

Abnormal bruising, Abnormal skin pigmentation, Anemia, Change in blood test results, Dizziness, Headache, Vomiting, Weakness, Diarrhoea, Nausea


Malaria prophylaxis, Severe falciparum malaria, Toxoplasmosis.

How it works

Sulfadoxine targets Plasmodium dihydropteroate synthase and dihydrofolate reductase. Sulfa drugs or Sulfonamides are antimetabolites. They compete with para-aminobenzoic acid (PABA) for incorporation into folic acid. The action of sulfonamides exploits the difference between mammal cells and other kinds of cells in their folic acid metabolism. All cells require folic acid for growth. Folic acid (as a vitamin) diffuses or is transported into human cells. However, folic acid cannot cross bacterial (and certain protozoan) cell walls by diffusion or active transport. For this reason bacteria must synthesize folic acid from p-aminobenzoic acid.

Common side effects

Nose bleed, Abdominal pain, Difficulty in urination, Fatigue, Glossitis, Headache, Inability to empty the urinary bladder, Feeling of discomfort


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Expert advice for MALOCIDE

  • Pyrimethamine when given with sulphonamide, it should be given with folic acid (vitamin) supplement.
  • Do not use pyrimethamine if you are allergic to pyrimethamine or any other ingredient.
  • Do not take pyrimethamine if you have megaloblastic anemia due to folate deficiency.
  • Do not take pyrimethamine if you have kidney or liver problems; fits (seizures); depression; bone marrow problems; stomach or bowel problems (eg, malabsorption syndrome); phenylketonuria, or alcoholism.

Frequently asked questions for MALOCIDE


Q. What is pyrimethamine is used for?
Pyrimethamine is used to treat toxoplasmosis and treat or prevent malaria infections along with other medicines.
Q. How does pyrimethamine work?
Pyrimethamine is an antiparasitic and works by killing the parasites or preventing their growth in the blood stream.


Content on this page was last updated on 31 December, 2014, by Dr. Varun Gupta (MD Pharmacology)