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03 Jun 2020 | 12:31 PM (IST)
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Macron 1000mg Injection

Prescription Required

Overview

Introduction

Macron 1000mg Injection is an antibiotic that fights bacteria. It is used to treat severe infections of the skin, lungs, stomach, urinary tract, blood and brain (eg. meningitis). It works by killing the bacteria that cause these problems. However, it will not treat a viral infection.

Macron 1000mg Injection is commonly used to treat critically ill patients admitted to the hospital. This medicine is given by drip/infusion or by direct injection into a vein, under the supervision of a healthcare professional. The dose depends on what type of infection you have, where it is in the body, and how serious it is. You should have your injections at the same time each day to get the most benefit and you should keep on taking this medicine for as long as you are prescribed it, even if your symptoms quickly improve. If you stop taking it too early the infection may return or worsen.

Some people may develop side effects like nausea, vomiting, diarrhea, rash, or local redness and swelling at the site of injection. These side effects are usually temporary and go away during treatment as your body adjusts to the medicine. Consult your doctor if these side effects bother you or do not go away.

Before starting treatment with this medicine, you should tell your doctor if you have epilepsy (seizures), liver or kidney problems or if you are allergic to any antibiotic. While using it, you may be advised blood tests to monitor your blood cell count and kidney function. This medicine is generally regarded as safe to use in pregnancy and breastfeeding if prescribed by your doctor.

Uses of Macron Injection

  • Severe bacterial infections

Benefits of Macron Injection

In Severe bacterial infections

Macron 1000mg Injection belongs to a group of medicines called carbapenem antibiotics. It works by killing bacteria which can cause serious infections. It is a versatile medicine used to treat many different types of bacterial infections such as infections of the brain (meningitis), lungs (pneumonia), abdomen, urinary tract, skin, blood, and heart. This medicine is usually given as an injection by a doctor or nurse.

Macron 1000mg Injection usually makes you feel better very quickly but you should continue taking it as prescribed even when you feel better to make sure that all bacteria are killed and do not become resistant.

Side effects of Macron Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Macron

  • Injection site reactions (pain, swelling, redness)
  • Nausea
  • Vomiting
  • Headache
  • Rash

How to cope with side effects?

The occurrence of side effects varies from person to person. The following are a few ways of dealing with some of the common side effects. However, consult your doctor if these persist.

  • Coping with Injection site reactions (pain, swelling, redness)
    Try to change the area of injection and the exact site of injection each time. Apply a cold compress to the injection site. These symptoms are usually mild and should only last a few hours. You can ask your doctor to recommend a medicine if it is bothering you.
  • Coping with Nausea
    You can help yourself by eating small, frequent meals rather than large ones and drinking plenty of fluids. Eat slowly. Avoid fatty, fried, spicy and very sweet foods. Eat cold or slightly warm food if the smell of cooked or cooking food makes you feel sick. Get plenty of fresh air. You could also try chewing ginger or drinking ginger tea. Eat bananas to replace potassium in your blood which can drop if you are sick (vomit). Use oral rehydration salts to replace vitamins and minerals lost through being sick. There are some medicines that can help you stop from feeling sick. Speak to your doctor if your condition does not improve.
  • Coping with Vomiting
    You can help yourself by eating small, frequent meals rather than large ones and drinking plenty of fluids. Eat slowly. Avoid fatty, fried, spicy and very sweet foods. Eat cold or slightly warm food if the smell of cooked or cooking food makes you feel sick. Get plenty of fresh air. You could also try chewing ginger or drinking ginger tea. Eat bananas to replace potassium in your blood which can drop if you are sick (vomit). Use oral rehydration salts to replace vitamins and minerals lost through being sick. There are some medicines that can help you stop feeling sick. Speak to your doctor if your condition does not improve.
  • Coping with Headache
    Make sure you rest and drink plenty of fluids. Rest in a quiet, dimly lit room. Do not sleep more than you normally would. Do not strain your eyes (for example by looking at a screen). Do not drink alcohol. Headaches are usually temporary and usually go away with time. But, if they last longer or get worse, ask your doctor to recommend a painkiller.
  • Coping with Rash
    There are many treatments for a wide range of skin problems. Avoid hot showers or baths because hot water can irritate the skin. Make sure to pat dry your skin after a bath or shower. Do not rub or scratch the affected area. Leave the skin exposed to the air as much as possible. Do not use perfumed soaps or deodorants. Water containing chlorine can make most skin problems worse, so avoid swimming. Avoid spicy foods, alcohol, tobacco smoke and caffeine as it may also make itching worse. Avoid excessive sun exposure. Always use sunscreen and protective clothing when outdoors. Moisturizers can be used regularly to soothe and hydrate the affected area. If it does not get better within a week, speak to a pharmacist or doctor.

How to use Macron Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Macron Injection works

Macron 1000mg Injection is an antibiotic. It kills bacteria by preventing them from forming the bacterial protective covering (cell wall) which is needed for them to survive.

Safety Advice

Alcohol
SAFE
Consuming alcohol with Macron 1000mg Injection does not cause any harmful side effects.
Pregnancy
SAFE IF PRESCRIBED
Macron 1000mg Injection is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.
Breastfeeding
SAFE IF PRESCRIBED
Macron 1000mg Injection is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
Driving
CONSULT YOUR DOCTOR
It is not known whether Macron 1000mg Injection alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react.
Kidney
CAUTION
Macron 1000mg Injection should be used with caution in patients with kidney disease. Dose adjustment of Macron 1000mg Injection may be needed. Please consult your doctor.
Liver
SAFE IF PRESCRIBED
Macron 1000mg Injection is safe to use in patients with liver disease. No dose adjustment of Macron 1000mg Injection is recommended.

What if you forget to take Macron Injection?

If you miss a dose of Macron 1000mg Injection, please consult your doctor.

Alternate Brands

For informational purposes only. Consult a doctor before taking any medicines.
Macron 1000mg Injection
₹1250.0/Injection
Carbapen M 1000mg Injection
Blue Cross Laboratories Ltd
₹44.5/ml of Injection
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Merotec 1000mg Injection
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₹767.2/Injection
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Merobax 1000mg Injection
Aristo Pharmaceuticals Pvt Ltd
₹1160/Injection
save 7%
₹2979/Injection
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₹3167.86/Injection
153% costlier

Quick Tips

  • Macron 1000mg Injection is an antibiotic that's usually only given in the hospital for serious infections.
  • Inform your doctor if you are allergic to penicillin or if you are taking any seizure medication before starting treatment with this medication.
  • Diarrhea may occur as a side effect. Inform your doctor if you develop severe stomach pain or if you find blood in your stools.
  • Your doctor may monitor your kidney function and blood count while you are having treatment with this medication.

Fact Box

Chemical Class
Carbapenem derivative
Habit Forming
No

Interaction with Drugs

Taking Macron with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Brand(s): Bencid
LIFE-THREATENING
Brand(s): Valkid, Valprosh, Cylenc SV
SERIOUS
Brand(s): Develpin, Epsoval, Divazen
SERIOUS

Patient Concerns

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Scar on face due to bacterial infections
Dr. Atul Jain
Dermatology
Pic is not clear, plz visit for proper opinion
I have a history of recurring yeast and bacterial vaginosis infections.
Dr. Sonu Balhara Ahlawat
Obstetrics and Gynaecology
Tab metrogyl 500 mg twice a day x 5 days and tab fluconazole 150 mg three doses alternate days
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Do you have any questions related to Macron 1000mg Injection ?

FAQs

Q. My friend has a history of epilepsy and she was on valproic acid while receiving treatment with Macron, still she had an episode of seizure. Why?

Any previous history with any other medication should be informed to the doctor before starting your treatment with Macron. Medicines like Macron can interfere with valproic acid which is used for the treatment of epilepsy, making it less effective. So, the reason for the recent episode of seizure could be the result of such drug interaction. Generally, in cases like these, the doctor prescribes a different medicine.

Q. Even though Macron is used for skin infections, can it cause any skin-related problems?

Serious skin reactions are rare, but some have been reported with the use of Macron. Therefore, before starting the treatment inform your doctor if you are allergic to any medicine or antibiotic. Serious skin reactions are a type of allergic reactions. But, if not properly managed then they can endanger life. So, if you notice any rash along with fever or peeling of the skin, discontinue the medication and inform your doctor.

Q. Is Macron a strong antibiotic? Which infections does it treat?

Macron is a broad-spectrum antibiotic which means it can treat a variety of bacterial infections. It is used to treat infection affecting the lungs (pneumonia) and complicated infections of the urinary tract, abdomen, and skin and soft tissue infections. Along with that, it is also helpful in treating bacterial infection of the membranes that surround the brain and spinal cord (meningitis) and infections that occur during or after delivery.

Q. Is Macron effective against bacteria only? Can it be used for any type of bacterial infection?

Yes, Macron is effective only against bacteria. It is not effective against virus or fungal infections. Macron is effective against some bacteria which include Staphylococcus aureus, Streptococcus pneumoniae, S. pyogenes, S. viridans group, etc. Therefore, its use against any other type of bacteria should be avoided.

Q. My cousin was receiving Macron for severe skin infection, but the medicine was stopped when she had a fit. Was the fit due to Macron?

There are reports which suggest the occurrence of seizures or fits with the use of Macron. However, fits are more likely to occur in patients with a history of seizures or a brain lesion (wound, ulcer, abscess or tumor) or patients having bacterial meningitis or compromised kidney function. Consult your doctor to understand the exact reason.

Q. For how long will I need to take Macron?

The length of the treatment will be decided by your doctor. The doctor will decide the dose depending on your general health, the type of infection you have and how well you respond to Macron. Consult your doctor if you are not sure.

Q. What if Macron does not suit me?

It is common to have minor side effects such as nausea, vomiting, diarrhea and headache with the use of Macron. However, these symptoms generally settle down with continued medication as the body adapts the medicine. If the side effects bother you, inform your doctor. The doctor will suggest an alternative medicine if required. Serious side effects with Macron are very rare. In case you develop serious side effects, seek immediate medical advice.

Q. Does it matter if I miss or stop Macron?

It is important that you do not stop the treatment without consulting your doctor. Stopping the treatment may bring back the infection or you may develop resistance to Macron. Similar results may be seen if you skip any dose or are forgetful in taking the suggested doses. Therefore, it is recommended that you do not miss doses. If you do, take the missed dose as soon as you can and take the next dose as planned so that you stick to the same overall daily dose.

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Disclaimer:

1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover all possible side effects, drug interactions or warnings or alerts. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

  1. Petri WA Jr. Penicillins, Cephalosporins, and Other β -Lactam Antibiotics. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. p. 1500.
  2. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 866-67.
  3. Meropenem. Wilmington, DE: AstraZeneca Pharmaceuticals; 1996 [revised Nov. 2013]. [Accessed 29 Mar. 2019] (online) Available from:External Link
  4. U.S. National Library of Medicine. Meropenem. [Accessed 29 Mar. 2019] (online) Available from:External Link
  5. Central Drugs Standard Control Organisation (CDSCO). [Accessed 28 Mar. 2019] (online) Available from:External Link

Manufacturer/Marketer Address

No 8,J-41,STREET NO-8, ANAND PARBHAT, NEW DELHI-5
Country of Origin: India
A licensed vendor partner from your nearest location will deliver Macron 1000mg Injection. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.
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