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23 Aug 2019 | 04:25 PM (IST)
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Macova 2.5 mg Tablet


Overview

Macova Tablet side effects

Common
  • Hot flushes
  • Fatigue
  • Increased sweating
  • Increased cholesterol level in blood

How to use Macova Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Macova 2.5 mg Tablet may be taken with or without food, but it is better to take it at a fixed time.

How Macova Tablet works

Macova 2.5 mg Tablet is an aromatase inhibitor. It works by decreasing the amount of estrogen (natural female hormone) produced in the body. This decrease in estrogen can slow down or stop the growth of some breast cancers that need estrogen to grow. In addition, it is also useful in infertility whereby it increases the release of certain hormones to stimulate the release of eggs from the ovaries.

Macova Tablet related warnings

Alcohol
SAFE
Consuming alcohol with Macova 2.5 mg Tablet does not cause any harmful side effects.
Pregnancy
UNSAFE
Macova 2.5 mg Tablet is highly unsafe to use during pregnancy. Seek your doctor's advice as studies on pregnant women and animals have shown significant harmful effects to the developing baby.
Lactation
UNSAFE
Macova 2.5 mg Tablet is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
Driving
UNSAFE
Macova 2.5 mg Tablet may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Kidney
SAFE IF PRESCRIBED
Macova 2.5 mg Tablet is safe to use in patients with kidney disease. No dose adjustment of Macova 2.5 mg Tablet is recommended.
However, there is limited information on the use of this medicine in patients with end stage kidney disease. Please consult with your doctor.
Liver
CAUTION
Macova 2.5 mg Tablet should be used with caution in patients with liver disease. Dose adjustment of Macova 2.5 mg Tablet may be needed. Please consult your doctor.

What if you miss a dose of Macova Tablet?

If you miss a dose of Macova 2.5 mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

Alternate Brands

For informational purposes only. Consult a doctor before taking any medicines.
Macova 2.5 mg Tablet
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Expert Advice

  • You have been prescribed Macova 2.5 mg Tablet for the treatment of breast cancer or infertility due to anovulation.
  • It can be taken with or without food.
  • Do not drive or do anything requiring concentration until you know how Macova 2.5 mg Tablet affects you.
  • It may cause increased sweating and hot flushes. Try to keep cool by wearing light and airy clothes.
  • Your doctor may monitor your cholesterol level and bone mineral density (BMD) regularly as Macova 2.5 mg Tablet can alter their levels.
  • Do not take Macova 2.5 mg Tablet if you are pregnant or breastfeeding 

Interaction with Drugs

Taking Macova with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Brand(s): Conjugase
LIFE-THREATENING
Brand(s): Evaride, Estratag, Lanadiol
LIFE-THREATENING
Brand(s): Vagimoist
LIFE-THREATENING
Brand(s): E Gen, Lynoral, Veronica
LIFE-THREATENING
Brand(s): Tibomax
LIFE-THREATENING

Patient Concerns

Questions Related to Macova

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This query is for my mother. She was diagnosed with breast cancer stage 1 a couple of years back. It was thus treated with surgery followed by radiology. The doctor has since put her on anastrozole 1mg tablet daily for 5 years. She has been taking altraz 1mg by alkem laboratories since inception but now we have found a same salt medicine named elinal 1mg by emcure pharmaceuticals with same composition. Is elinal an equally effective medicine and can be taken in lieu of altraz? Reason for switching: elinal costs 80% less than altraz.
Dr. Megha Tuli
Gynaecologist
Hi PATIENT understand your concern. Emcee is a very good brand too. There is technically no difference in the two medicines. However I would suggest you verify with your treating doctor in this case because in case later something goes wrong in future, your doctor will only blame you that you checnged the medicine without consulting him and that is reason the patient has deteriorated. Cancer is known to be notorious. I have myself lost 2 very close family members to breast cancer. Do not take me wrong. I'm only asking you to verify with your doctor so that in future you face no problems in this account.
I had a 1-2 Stage breast cancer and mastectomy was done for left breast in 2011. Earlier I was taking Tamoxifen Citrate 20mg. Now, prescribed Altraz 1mg. Which is better and can I continue with Tamoxifen as Altraz is too costly.
Dr. Vijay Sharnangat
Cancer Specialist
Why this tablet is changed, has your doctor told you about that why he is changing your medicines.
arrow
Do you have any questions related to Macova 2.5 mg Tablet?

FAQs

Q. Why have I been prescribed Macova?

Macova is an aromatase inhibitor. It is generally prescribed to treat breast cancer in women who no longer have periods, either due to menopause or after surgery or chemotherapy. It is also used to treat infertility caused due to anovulation (during menstrual cycle egg cell from ovaries is not released).

Q. How does Macova work?

Macova is also known as an anti-estrogen drug. It is called so because it acts by reducing the production of estrogen in your body by blocking the enzyme aromatase, which is responsible for production of estrogen. Estrogen stimulates the production of certain types of breast cancer in your body. These cancers are called "estrogen-dependent cancers". Reducing the production of estrogen may prevent the cancer from growing.

Q. For how long should I take Macova?

If the breast tumor is in advanced stage or has spread to other parts of the body, it is recommended that you continue taking Macova till the tumor shows progression. In cases where Macova is given after tamoxifen (another anti-estrogen used for breast cancer) or surgery, it should be given for 5 years or until tumor comes back, whichever is first. It can also be given as a sequential treatment; 2 years of Macova followed by 3 years of tamoxifen.

Q. If I am taking irbesartan to control my blood pressure, can I take Macova?

Yes, you can take irbesartan and Macova together. However, be careful and keep a regular check on your blood pressure since Macova may increase your blood pressure. Consult your doctor in case you have problems controlling your blood pressure.

Q. Does Macova affect vision?

Although it is very uncommon but Macova may cause cataract. So, if you experience blurred vision or eye irritation, consult your doctor immediately.

Q. My friend who is taking Macova often sweats a lot. Is it because of Macova?

This could be a sign of hot flushes which is a very common side effect of Macova. It happens due to decreased estrogen levels. The frequency of hot flushes reduces once your body adjusts to Macova. However, in some people the flushes and sweats may continue during the treatment and stop a few months after the treatment finishes. You can consult your doctor who will provide you a remedy if it is very bothersome.

Q. What are the serious side effects of Macova?

The serious side effects do not occur in everyone and very few people experience them. The serious side effects of Macova include stroke, angina, heart attack, blood clotting, cataract, osteoporosis and severe skin reactions.

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Disclaimer: 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover all possible side effects, drug interactions or warnings or alerts. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.
References
  1. Moy B, Lee RJ, Smith M. Natural Products in Cancer Chemotherapy: Hormones and Related Agents. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. New York, New York: McGraw-Hill Medical; 2011. p. 1762.
  2. Masters SB. Hypothalmic & Pituitary Hormones. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 718.
  3. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 786-87.
  4. Drugs.com. Letrozole. [Accessed 03 Apr. 2019] (online) Available from:External Link
  5. Letrozole. Barnstaple, Devon: Accord-UK Ltd.; 2009 [revised 20 Nov. 2017]. [Accessed 25 Jan. 2019] (online) Available from:External Link
  6. Letrozole. East Hanover, New Jersey: Novartis Pharmaceuticals Corporation; 1997 [revised Jan. 2014]. [Accessed 03 Apr. 2019] (online) Available from:External Link
  7. Central Drugs Standard Control Organisation (CDSCO). [Accessed 04 Apr. 2019] (online) Available from:External Link
Manufacturer/Marketer Address
Nand Vihar Colony, Narmada Road, Rau Tehsil ,Indore,Madhya Pradesh,453331
A licensed pharmacy from your nearest location will deliver Macova 2.5mg Tablet. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your prescription and the availability of this medicine.
Best Price
₹144
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5 tablets in 1 strip
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