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MD (Pharmacology), MBBS
Last updated:
27 Dec 2019 | 01:08 PM (IST)
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Lyphidox 10 Injection


Overview

Introduction

Lyphidox 10 Injection is used in the treatment of various types of cancers of blood, breast, lung, ovaries and soft tissues. It can be used on its own, or sometimes given together with certain other medicines as part of combination chemotherapy.

It is given as a drip or infusion vein with extreme caution by a qualified medical professional. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to. It makes contraceptive pills less effective, so it advised to both male and female to use reliable contraception during the treatment.

The most common side effects of this medicine include vomiting, allergic reaction, nausea, mouth sore, and hair loss.  If these bother you or appear serious, let your doctor know. There may be ways of reducing or preventing them. It is known to reduce the number of blood cells in your blood thereby, increasing the susceptibility to infections. Infections can sometimes be life threatening. Regular blood tests are required to monitor your blood cells along with kidney, liver and heart function during treatment with this medicine.

Before taking this medicine, tell your doctor if you have severe liver or heart related problems, or if you are pregnant, or breastfeeding.  Your doctor should also know about all other medicines you are taking as many of these may make this medicine less effective or change the way it works.

Uses of Lyphidox Injection

Side effects of Lyphidox Injection

Common
  • Vomiting
  • Allergic reaction
  • Nausea
  • Mouth sore
  • Hair loss
  • Stomach pain
  • Eye disorder
  • Increased thirst
  • Heart beat irregular
  • Nail disorder

How to use Lyphidox Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Lyphidox Injection works

Lyphidox 10 Injection is an anti-cancer medication. It works by suppressing the activity of an enzyme (topoisomerase II) involved in DNA multiplication of the cancer cells. It also forms harmful chemicals (free radicals) which cause DNA damage. This slows the growth of cancer cells and eventually kills them.

Safety Advice

Alcohol
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Lyphidox 10 Injection. Please consult your doctor.
Pregnancy
CONSULT YOUR DOCTOR
Lyphidox 10 Injection is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
Breastfeeding
UNSAFE
Lyphidox 10 Injection is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
Driving
UNSAFE
Lyphidox 10 Injection may cause side effects which could affect your ability to drive.
As there is a frequent occurrence of nausea and vomiting with Lyphidox 10 Injection so driving should be discouraged.
Kidney
SAFE IF PRESCRIBED
Lyphidox 10 Injection is safe to use in patients with kidney disease. No dose adjustment of Lyphidox 10 Injection is recommended.
However, inform your doctor if you have any kidney disease.
Liver
CAUTION
Lyphidox 10 Injection should be used with caution in patients with liver disease. Dose adjustment of Lyphidox 10 Injection may be needed. Please consult your doctor.

Alternate Brands

For informational purposes only. Consult a doctor before taking any medicines.
Lyphidox 10 Injection
₹169.83/Injection
₹82.67/ml of Injection
save 51%
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Quick Tips

  • Inform your doctor if you have a history of heart problems or low production of blood cells from the bone marrow.
  • Inform your doctor if you have received doxorubicin or any other anthracycline as anti-cancer therapy or radiation to the upper body.
  • You may need to perform blood count, heart/kidney/liver function tests before therapy.
  • Take precaution while taking doxorubicin as you may develop infection and bleeding episodes.
  • This therapy may cause damage to heart muscle or heart failure, the risk is more if radiation was used as treatment before for upper body.
  • Doxorubicin therapy causes high levels of uric acid in blood, also urine may turn red on therapy and this is not a sign of any damage. 
  • Live or attenuated vaccines (like polio, malaria) should not be taken during therapy and contact with persons who receive them must be avoided.
  • Women who are planning to become pregnant should be counselled about the toxic effect of this drug on babies. They should use two effective methods of contraception while on this therapy and 6 months after stopping it.
  • Men who are going to use this therapy should not father a child while on this therapy and 6 months post it. They should also seek guidance and counselling on sperm conservation before taking this therapy.
  • Do not drive or operate machinery as doxorubicin may cause nausea and vomiting.

Patient Concerns

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Can blood cancer patients 1st stage do sex with normal girl Sir a blood cancer patients do sex with normal girl can any problem or cause doing with girl or side effect give suggestions Thanks
Dr. Vijay Sharnangat
Medical Oncology and Hematology
Wait till blood cancer gets cured.
Blood Cancer. Is there any medicine to cure blood cancer.
Dr. Aanchal Maheshwari
Ayurveda
Case has to be seen in person
arrow
Do you have any questions related to Lyphidox 10 Injection ?

FAQs

Q. How does doxorubicin work?

Doxorubicin is anti-cancer or antineoplastic chemotherapy drug that belongs to a class of medication called anthracyclines. It slows down or stops the growth of cancer cells by interfering with DNA of the cancer cell

Q. Is doxorubicin a vesicant?

Yes doxorubicin is a vesicant (irritant).

Related Products

Disclaimer: 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover all possible side effects, drug interactions or warnings or alerts. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.
References
  1. Chabner BA, Bertino J, Cleary J, et al. Cytotoxic Agents. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 1714-15.
  2. Chu E, Sartorelli AC. Cancer Chemotherapy. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 952.
  3. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 431-33.
  4. Doxorubicin hydrochloride. Sandwich, Kent: Pfizer Limited; 2009 [revised Feb. 2016]. [Accessed 25 Jan. 2019] (online) Available from:External Link
  5. Chaves RG, Lamounier JA. Breastfeeding and maternal medications. J Pediatr (Rio J). 2004;80(5 Suppl):S189-S198. [Accessed 19 Mar. 2019] (online) Available from:External Link
  6. Central Drugs Standard Control Organisation (CDSCO). [Accessed 27 Mar. 2019] (online) Available from:External Link
Manufacturer/Marketer Address
Alkem Laboratories Limited, Devashish Building, Alkem House, Senapati Bapat Road, Lower Parel, Mumbai - 400 013.
Best Price
₹135.86
MRP169.83  Get 20% OFF
This price is valid only on the orders above ₹500
1 Injection in 1 vial
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