Medicine Overview of Lethyrox Tablet
Uses of Lethyrox Tablet
Lethyrox 12.5mcg Tablet is used in the treatment of hypothyroidism.
Side effects of Lethyrox Tablet
Anxiety, Vomiting, Diarrhoea, Palpitations, Nervousness, Weight loss, Tremor.
How to use Lethyrox Tablet
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. It is better to take Lethyrox 12.5mcg Tablet empty stomach.
How Lethyrox Tablet works
Lethyrox 12.5mcg tablet is a synthetic version of a hormone produced by the thyroid gland. It works by replacing the thyroid hormones that your thyroid gland cannot produce and relieves the symptoms of hypothyroidism ( tiredness, weight gain, and depression).
In Depth Information on Lethyrox Tablet
Expert advice for Lethyrox Tablet
- Lethyrox must be taken on an empty stomach. No food, milk, or tea should be taken 1 hour before and 2 hours after taking this medicine.
- Though it starts working within 1 to 2 weeks, you may have to wait for 6 to 8 weeks to get the full effect.
- Inform your doctor if you have diarrhoea, nervousness, irritability, feeling of a heartbeat, sleep disturbances, shaking hands, or chest pain. Your doctor may adjust your dose.
- Leave a gap of at least 4 hours before taking any antacids, calcium or iron supplements, and multivitamins, as these may interfere with the effect of the medicine.
- Regular blood tests are necessary as advised by your doctor.
- Inform your doctor before changing the brand of Lethyrox as all brands may not have the same effect.
Special precautions for Lethyrox 12.5mcg Tablet
Interaction with alcohol is unknown. Please consult your doctor.
Lethyrox 12.5mcg Tablet is safe to use during pregnancy.+more
Adequate and well-controlled human studies have shown low or no risk....
Adequate and well-controlled human studies have shown low or no risk.
Lethyrox 12.5mcg Tablet is safe to use during lactation. Hu+more
man studies have shown that either the drug does not pass into the breastmilk in significant amount or is not expected to cause toxicity to the baby....
Lethyrox 12.5mcg Tablet does not usually affect your ability to drive.
There is limited information available on the use of Lethyro+more
x 12.5mcg Tablet in patients with kidney disease. Please consult your doctor....
There is limited information available on the use of Lethyro+more
x 12.5mcg Tablet in patients with liver disease. Please consult your doctor....
If you miss a dose of Thyroxine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Frequently asked questions for Lethyrox 12.5mcg Tablet
Frequently asked questions for Thyroxine
No. Lethyrox is not a beta-blocker. It is a hormone synthesised by the thyroid gland present in the neck region. It maintains normal growth & development, body temperature & energy levels.
No. Lethyrox is not a blood thinner. It is a hormone used for the treatment of hypothyroidism (decreased thyroid hormone). Blood thinners are medicines which prevent abnormal clot formation.
The dose is individualised on the basis of clinical response and biochemical tests. Regular monitoring of thyroid stimulating hormone (TSH) and Lethyrox is recommended when starting therapy or changing the dose. Do not change the dose or stop the medicine without consulting your doctor.
No, Lethyrox is not a growth hormone. It is a hormone synthesized by the thyroid gland present in the neck region. Growth Hormone, on the other hand, is secreted by the pituitary gland present in the brain. Lethyrox is required for the proper functioning of growth hormone.
No, Lethyrox is not a neurotransmitter. Lethyrox is a hormone secreted directly into the blood by the thyroid gland. The blood then takes it to the target organs in the body. A neurotransmitter, on the other hand, transmits impulses from one nerve cell to the other in the brain.
Tropic hormones are hormones that have other endocrine glands as their target. Most tropic hormones are produced and secreted by the pituitary gland in the brain. The thyroid gland secretes Lethyrox, which targets the hypothalamus and therefore can be considered a tropic hormone.
No. Lethyrox is not a protein. The normal thyroid gland secretes two thyroid hormones - triiodothyronine (T3) and tetraiodothyronine (T4 or Lethyrox). More than 99% of these hormone circulating in the blood as bound to carrier proteins, Lethyrox-binding globulin, synthesised in the liver.
Lethyrox is neither a peptide nor a steroid. Lethyrox is an amino acid (tyrosine) derived hormone. (Amino acids are tiny building blocks of proteins, but they cannot be called proteins by themselves unless a number of them are connected in a sequence).
Yes. Lethyrox can produce side effect as weight loss. It is usually due to excessive dose. However, it should not be used for treat obesity.
Yes. Lethyrox can be used as a hormone replacement therapy to compensate the deficiency of thyroid hormone in the body.
Yes. Lethyrox is a hormone secreted from the thyroid gland. It causes increased oxygen consumption by most tissues of the body, increases the basal metabolic rate and the metabolism of carbohydrates, lipids and proteins.
Yes. Lethyrox is a slow-acting drug. It acts through receptors situated in the nucleus of a cell and results in the formation of various protein to target its action hence Lethyrox takes some time to act.
No. Lethyrox is not a diuretic. It is a hormone secreted by the thyroid gland.
If Lethyrox is taken with food or even just before food the absorption of the Lethyrox from the intestine decreases from the intestine and hence the desired effects are not seen. Similarly, if the dose of the Lethyrox given is lesser than what is required by the body then it might not work.
Lethyrox poisoning occur if an excessive dose is taken. It present as a headache, hyperactivity, nervousness, anxiety, irritability, heat intolerance, fever, excessive sweating, palpitations, tachycardia, arrhythmias, increased pulse and blood pressure. Inform your doctor as soon as possible.
Lethyrox is required for the normal functioning of the body. Research has shown that thyroid hormone significantly affects the erythropoiesis and increases red blood cell synthesis. Lethyrox is not approved to treat anemia (decreased red cell count).
Q. In which condition does Lethyrox is used along with carbimazole?
Lethyrox is used with carbimazole in the treatment of Graves disease or hyperthyroidism. Studies have shown it is used as block–replace regimen which means the option of maintaining the high dose of antithyroid drugs along with adding levothyroxine to maintain normal thyroid state.
Q. Can I take an antidepressant along with Lethyrox?
No. There are noted interactions between Lethyrox and few antidepressants which lead to increased adverse effects of both the drugs so consult your doctor and do inform him before prescribing any of the medication.
Q. What is the effect of grapefruit juice on the absorption of Lethyrox?
Grapefruit juice slightly decreases the absorption of levothyroxine when taken together otherwise there is no major interaction between these two.
Q. Can I take Lethyrox with tea?
No. Lethyrox cannot be taken with tea. Though major interactions are not noted when taken with together the absorption of the Lethyrox from the intestine decreases and hence the desired effects are not achieved.
Q. Can I take vitamins with Lethyrox and what would be its effects?
Yes. Vitamins can be added to your diet and can be taken with Lethyrox, but you should not take vitamin supplement within four hours of taking your thyroid medication.
Q. Can I take omeprazole along with Lethyrox?
No. Omeprazole should not be taken with Lethyrox. Omeprazole increases the gastric pH and interferes with the absorption of the Lethyrox.
Q. What is the effect of iodine while I take Lethyrox?
Iodine, when given with Lethyrox, may increase thyroid hormone secretion, which may result in hyperthyroidism. Hyperthyroidism may develop over several weeks and may persist for several months after therapy discontinuation.
Q. Can I take Lethyrox with iron tablets?
No. Lethyrox should not be taken with the iron tablet. The absorption of Lethyrox is decreased when taken together. You should take them with a gap of 4 hours between them.
If Lethyrox is taken with food or even just before food the absorption of the Lethyrox from the intestine decreases and hence the desired effects are not seen. So Lethyrox should always be taken in empty stomach preferably one-half to one-hour before breakfast.
No. Lethyrox should not be taken with milk. The absorption of Lethyrox is decreased when taken with milk. It should be taken 1 hour before and 2 hours after taking milk.
No. Lethyrox should not be taken with calcium. The absorption of Lethyrox is decreased when taken with calcium. You should take them with a gap of 4 hours between them.
Q. Can I take Lethyrox with coffee?
No. Lethyrox should not be taken with coffee. The absorption of Lethyrox is decreased when taken with coffee. It should be taken 1 hour before and 2 hours after taking coffee.
No. Lethyrox should not be used to treat obesity. It can cause weight loss as a side effect but it should not be used for the treatment of obesity as it can cause serious life-threatening side effects if given with other weight reducing medications.
No. Lethyrox is not approved for use in depression. But some of the research studies have shown that adding Lethyrox to the antidepressant medication therapy has increased the effectiveness of antidepressant therapy in the patients.
Lethyrox treats hypothyroidism (decreased thyroid hormone) and associated complications leading to increases chances of conceiving. Consult your doctor before starting Lethyrox as failure to conceive is not merely due to decreased thyroid hormone but due to several other factors. Always start the medicine consulting with the doctor.
It is preferred to take Lethyrox in morning on empty stomach. Research has shown that even if it is given in the evening, it shows the same effects as compared to morning. It is not practised because of ensuring an empty stomach by the patient.
Yes. Lethyrox can be used but at a lower dose or given on an alternate day. There are high chances of side effects in a person with the cardiac disease like an increase in heart rate, cardiac wall thickness, and cardiac contractility and it may precipitate angina or irregular heart rhythms. Inform your doctor if you have heart disease. You may adjust the dose.
The serious side effects of Lethyrox are usually due to excessive doses, so symptoms are similar to hyperthyroidism. It may cause diarrhoea, vomiting, weight loss with increased appetite, palpitations, angina, insomnia and restlessness. Inform your doctor if you have these symptoms.
No. Lethyrox should not be taken with an antacid. The absorption of Lethyrox is decreased when taken together. You should take them with a gap of 4 hours between them.
Thyroid function test should be measured three months after starting treatment or change in dose.
Yes. Lethyrox can be taken with MAO inhibitors. Consult your doctor before starting these medications.
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