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PhD (Pharmacology), PGDPRA
Reviewed By
MD (Pharmacology), MBBS
Last updated on:
12 Aug 2019 | 05:27 PM (IST)
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Lenzest 25 mg Capsule


Overview

Uses of Lenzest Capsule

Lenzest Capsule side effects

Common
  • Headache
  • Weakness
  • Nausea
  • Rash
  • Breathlessness
  • Dizziness
  • Sleepiness
  • Edema (swelling)
  • Loss of appetite
  • Decreased white blood cell count
  • Decreased calcium level in blood
  • Weight gain
  • Muscle weakness
  • Fatigue
  • Fever
  • Anxiety
  • Blood clots
  • Dry skin
  • Weight loss
  • Confusion
  • Decreased white blood cell count (neutrophils)
  • Neuropathy
  • Constipation
  • Tremor

How to use Lenzest Capsule

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Lenzest 25 mg Capsule may be taken with or without food, but it is better to take it at a fixed time.

How Lenzest Capsule works

Lenzest 25 mg Capsule is an anti-cancer medication. It works by enhancing the immune system that indirectly attacks the cancer cells. It prevents the growth of new blood vessels within the tumor. It also restricts the production of chemical messengers (cytokine and growth factor) which are responsible for the growth of cancer cells. This is how it works against cancer.

Lenzest Capsule related warnings

Alcohol
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Lenzest 25 mg Capsule. Please consult your doctor.
Pregnancy
UNSAFE
Lenzest 25 mg Capsule is highly unsafe to use during pregnancy. Seek your doctor's advice as studies on pregnant women and animals have shown significant harmful effects to the developing baby.
Lactation
CONSULT YOUR DOCTOR
Lenzest 25 mg Capsule is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Driving
UNSAFE
Lenzest 25 mg Capsule may cause side effects which could affect your ability to drive.
You may feel dizzy, tired, sleepy, have vertigo or blurred vision after taking Lenzest 25 mg Capsule and this may affect your ability to drive.
Kidney
CAUTION
Lenzest 25 mg Capsule should be used with caution in patients with kidney disease. Dose adjustment of Lenzest 25 mg Capsule may be needed. Please consult your doctor.
Liver
CAUTION
Lenzest 25 mg Capsule should be used with caution in patients with liver disease. Dose adjustment of Lenzest 25 mg Capsule may be needed. Please consult your doctor.

Alternate Brands

For informational purposes only. Consult a doctor before taking any medicines.
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Expert Advice

  • You may be monitored with regular blood tests before and during the treatment as lenalidomide may cause a fall in the white blood cells and platelets, required to fight infection, Hemoglobin and blood clotting.
  • Avoid activities that may cause bruising or injury and avoid contact with people who have colds or infections.
  • It makes your skin sensitive towards sunlight. Apply sunscreen or wear protective while going out. 
  • It may cause dehydration. Drink plenty of water to stay hydrated while taking medication.
  •  It is not recommended for use in children and adolescents under 18 years.
  • You should use proper contraceptive methods at least 4 weeks before, during and until 4 weeks after stopping treatment. 
  • Woman of childbearing potential will be required to undergo pregnancy tests before and after the treatment.
  • You should inform your doctor or dentist that you are taking Lenzest 25 mg Capsule before you receive any medical or dental care, emergency care, or surgery.
  • It may cause dizziness or sleepiness. Do not drive or do anything requiring concentration until you know how it affects you.
  • You may be at risk of developing acute myelogenous leukemia, Hodgkin lymphoma tumor lysis syndrome, fatal liver problems, severe skin reactions, and fatal heart problems during treatment with Lenzest 25 mg Capsule. You should discuss in advance the benefits and risks of taking this medicine. 

Patient Concerns

Questions Related to Lenzest

arrow
Multiple myeloma can be cured or not
Dr. Rohan Khandelwal
Cancer Specialist
Yes, if diagnosed at the right stage
Please tell me the interpretation of the attach report, if possible. Also guide for further treatment process.
Dr. Sanjay Singh Rai
Cancer Specialist
U r having multiple myeloma
arrow
Do you have any questions related to Lenzest 25 mg Capsule?

User Feedback


FAQs

Q. Can I take Lenzest empty stomach?

Lenzest may be taken with or without food. Always take it exactly as prescribed by your doctor. Do not crush, cut or chew the capsules. Swallow it whole with water. You should take Lenzest at about the same time on the scheduled days.

Q. Can Lenzest be given to patients who are on dialysis?

Yes, Lenzest is given to dialysis patients after the dialysis is done. However, the doctor may adjust the dose if needed in patients undergoing.

Q. What are the side effects of Lenzest?

Lenzest may cause side effects which include diarrhea, constipation, stomach pain, loss of appetite, weight loss, weakness, dizziness, change in ability to taste, and pain or burning of the tongue, mouth, or throat. The medicine may also cause decreased sense of touch, burning or tingling in the hands or feet, difficulty falling asleep or staying asleep, depression, and joint, muscle, bone, or back pain. You may also experience sweating, dry skin, abnormal hair growth in women, uncontrollable shaking of a part of the body, decrease in sexual desire or ability or painful, frequent, or urgent urination. Tell your doctor if any of these symptoms are severe or do not go away.

Q. What are the serious side effects of Lenzest?

The serious side effects of Lenzest include difficult breathing or swallowing, hoarseness or swelling of the face, throat, tongue, lips, eyes, arms, hands, feet, ankles, or lower legs. Some of the serious side effects may also include seizures, rash, skin pain, fast, slow, pounding, or irregular heartbeat or blistering, peeling, or shedding skin. It may also cause swollen glands in the neck, muscle cramps, pain in the upper right part of the stomach, yellowing of the skin or eyes, dark colored urine, tiredness, or bloody, cloudy, or painful urination and increased or decreased urination. Call your doctor immediately if you get any of these side effects.

Q. Can Lenzest cause cancer?

People with multiple myeloma (a form of cancer that begins in plasma cells, a type of white blood cell) who receive melphalan (chemotherapy) and a blood stem cell transplant with the addition of Lenzest have a higher risk of developing new cancers. These types of cancers may include certain blood cancers (acute myelogenous leukemia or AML) and a type of lymphoma called Hodgkin lymphoma. Talk to your doctor about your risk of developing new cancers if you are taking Lenzest.

Q. Do I need to get any blood tests done while on Lenzest?

Your doctor will ask you to have a blood test before treatment and every week for the first 8 weeks of treatment. You may need to continue taking the blood tests at least every month after treatment with Lenzest ends. Frequent blood tests are important as Lenzest may decrease the blood cells that help fight infection (white blood cells) and help the blood to clot (platelets).

Q. Do I need to use birth control methods while using Lenzest?

Women who can become pregnant must use two acceptable forms of birth control for 4 weeks before they begin taking Lenzest. Continue using contraceptives during your treatment, including the times when your doctor tells you to temporarily stop taking Lenzest, and for 4 weeks after your final dose. In men, Lenzest may pass into the semen while they are on treatment. Therefore, men must always use a latex condom every time they have sexual contact, even if they have had a vasectomy (surgery that prevents a man from causing a pregnancy). Use the contraceptive while you are taking Lenzest, during any breaks in your treatment, and for 4 weeks after your final dose.

Related Products

Disclaimer: 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover all possible side effects, drug interactions or warnings or alerts. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.
References
  1. Chabner BA, Barnes J, Neal J, et al. Targeted Therapies: Tyrosine Kinase Inhibitors, Monoclonal Antibodies, and Cytokines. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. p. 1742.
  2. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 784-85.
  3. Lenalidomide. Summit, New Jersey: Celgene Corporation. [Accessed 26 Mar. 2019] (online) Available from:External Link
  4. Central Drugs Standard Control Organisation (CDSCO). [Accessed 26 Mar. 2019] (online) Available from:External Link
Manufacturer/Marketer Address
90, Delhi - Jaipur Road, Sector 32, Gurugram, Haryana 122001
4753
MRP5868.05  19% OFF
10 capsules in 1 strip
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