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Composition for LANCET

Metronidazole(400 mg),Tetracycline(333 mg)

food interaction for LANCET

alcohol interaction for LANCET

pregnancy interaction for LANCET

lactation interaction for LANCET

Avoid Lancet 400mg/333mg tablet with grapefruit juice.
Lancet 400mg/333mg tablet may cause symptoms such as flushing, increased heartbeat, nausea, thirst, chest pain and low blood pressure with alcohol (Disulfiram reactions).
Lancet 400mg/333mg tablet is unsafe to use during pregnancy.
There is positive evidence of human fetal risk, but the benefits from use in pregnant women may be acceptable despite the risk, for example in life-threatening situations. Please consult your doctor.
Lancet 400mg/333mg tablet is probably unsafe to use during breastfeeding. Please consult your doctor.


Metronidazole(400 mg)


Metronidazole is used to treat infections of the gum and dental cavity, pelvic area, brain, lung, bones, stomach, intestines, genital tract and blood. It is used to treat pressure sores and leg ulcers and prevent infections after surgery.

How it works

Metronidazole belongs to a class of medicines called as nitroimidazole antibiotics. It works by inhibiting energy production and killing the bacteria and parasites that cause infections in the body.

Common side effects

Allergic reaction, Itching, Skin rash, Joint pain, Bitter taste, Dark colored urine, Dry mouth, Furry tongue, Loss of appetite, Mouth irritation, Throat irritation, Nasal congestion, Stomach upset, Numbness, Tingling sensation, Weakness, Fever, Vomiting, Diarrhoea
Tetracycline(333 mg)


Tetracycline is used in the treatment of respiratory tract infection, urinary tract infection, sexually transmitted disease, eye infection, skin infection, rickettsial infection (infection caused by organism called as rickettsia) and as an alternative drug in treatment of leptospirosis (an infectious bacterial disease occurring in rodents, dogs, and other mammals, which can be transmitted to humans), brucellosis (headache, sickness, fever, swollen lymph nodes), psittacosis (headache, nose bleeds, shivering and fever), plague (painful swelling of the lymph nodes), cholera (severe sickness and diarrhoea), gas-gangrene (is a bacterial infection that produces gas in tissues in necrosed tissues) and tetanus (a serious bacterial disease that affects nervous system, leading to painful muscle contractions, particularly of jaw and neck muscles).

How it works

Tetracycline is a broad spectrum antibiotic that belongs to class of drugs called tetracyclines. It acts by inhibiting the growth and multiplication of bacteria by interfering in their protein synthesis mechanism.

Common side effects

Changes in skin color, Dark colored urine, Diarrhoea, Headache, Rectal itching, Skin redness, Sore mouth, Stomach upset, Tooth discolouration, Vaginal itching, Yellow discoloration of skin, Yellow discoloration of eye


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Expert advice for LANCET

  • Take these tablets without crushing during or just after a meal with water.
  • Consult your doctor before using metronidazole if you have liver disease, nervous disorders or if you are undergoing kidney dialysis.
  • Inform your doctor if you are taking medicines such as warfarin (and other blood-thinners), astemizole, lithium, phenytoin, phenobarbital, disulfiram and vitamins.
  • Do not take the medicine if you are allergic to metronidazole or to any other content in the medicine.
  • Do not take alcohol while taking this medicine as it may lead to headaches, upset stomach, vomiting, stomach cramps, sweating and flushing (redness of the face).
  • Do not drive or operate heavy medicine after taking the medicine as it may temporarily cause dizziness and problems in vision.
  • Avoid excessive exposure to sunlight and wear protective clothing, sunglasses or apply sunscreen before stepping out in the sun as this drug may increase the sensitivity to sunlight.

Frequently asked questions for LANCET


Q. Is metronidazole safe?
Yes, metronidazole is a relatively safe drug if used in prescribed dose and for prescribed duration as advised by your doctor.
Q. What is metronidazole?
 Metronidazole is an antibiotic.
Q. Is it antibiotic or pain killer?
Metronidazole is an antibiotic and not pain killer.

Q. What it is used for?
It is used for infections of the dental cavity, ears, sinus, throat, lungs, stomach, intestine, brain and bones.
Q. Is metronidazole same as Flagyl?
Yes. Flagyl is a branded medicine containing metronidazole.
Q. Does metronidazole cure STDs or yeast infections?
Metronidazole cures genital infections like bacterial vaginosis and gonorrhea. It does not cure chlamydia or vaginal yeast infections.
Q. Does metronidazole affect birth control?
There is no evidence of metronidazole affecting contraception. Please consult your doctor to confirm whether you require a secondary birth control measure while taking metronidazole.
Q. Is metronidazole an OTC product?
No, metronidazole is not an OTC product.
Q. Can metronidazole cause nausea, vomiting, constipation or irregular monthly periods?
Metronidazole may cause nausea, vomiting, constipation or upset stomach. However, there is no evidence of metronidazole affecting monthly periods. If you notice any such symptoms, please consult your doctor.


Content on this page was last updated on 31 May, 2014, by Dr. Varun Gupta (MD Pharmacology)