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KOMBIGLYZE 5MG/1000MG TABLET XR

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Rs.357for 1 strip(s) (7 tablet xr each)
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Composition FOR KOMBIGLYZE

Saxagliptin(5mg),Metformin(1000mg)

food interaction for KOMBIGLYZE

alcohol interaction for KOMBIGLYZE

pregnancy interaction for KOMBIGLYZE

lactation interaction for KOMBIGLYZE

food
alcohol
pregnancy
lactation
There is no data available. Please consult doctor before consuming the drug.
Taking alcohol together with saxagliptin may affect blood glucose levels in patients with diabetes.
Taking metformin with alcohol may cause lactic acidosis and you may experience malaise, respiratory distress, slow or irregular heartbeat, somnolence, abdominal upset, or other unusual symptoms.
UNSAFE
Kombiglyze 5mg/1000mg tablet xr is probably safe to use during pregnancy.
Animal studies have shown low or no adverse effect on the foetus, however, there are limited human studies. Please consult your doctor.
PROBABLY SAFE
Unknown. Human and animal studies are not available. Please consult your doctor.

SALT INFORMATION FOR KOMBIGLYZE

Saxagliptin(5mg)

Uses

Saxagliptin is used in the treatment of type 2 diabetes

How it works

Saxagliptin increases the amount of insulin released by the pancreas, which in turn lowers the blood glucose levels.

Common side effects

Headache, Upper respiratory tract infection, Hypoglycaemia (Low blood sugar level) in combination with insulin or sulphonylurea, Nasopharyngitis
Metformin(1000mg)

Uses

Metformin is used in the treatment of type 2 diabetes and polycystic ovary syndrome (pcos).

How it works

Metformin restores the body's ability to use insulin, lowering the blood sugar levels. Metformin also decreases the amount of glucose absorbed from food in the intestine and decreases glucose production in the liver.

Common side effects

Nausea, Vomiting, Altered taste, Abdominal pain, Diarrhoea, Loss of appetite

COMMON DOSAGE FOR KOMBIGLYZE 5MG/1000MG TABLET XR

Patients taking KOMBIGLYZE 5MG/1000MG TABLET XR

  • 91%
    Once A Day
  • 5%
    Twice A Day
  • 2%
    Twice A Week
  • 2%
    Thrice A week
  • 1%
    Alternate Day

SUBSTITUTES FOR KOMBIGLYZE

No substitutes found

Top Diabetologists

Expert advice FOR KOMBIGLYZE

  • Saxagliptin is a well tolerated and safe anti-diabetic drug and does not cause very low blood sugar levels and weight gain.
  • Take Saxagliptin with water at any time of the day with or without food. Do not chew or crush the tablets.
  • You would be at an increased risk of hypoglycemia (low blood sugar level) when insulin and sulfonylureas are also given along with, a dose adjustment may be needed. Do not change the dose yourself.
  • Inform your doctor if you have ever been diagnosed with kidney or liver problems.
  • Saxagliptin can cause acute pancreatitis (swelling of your pancreas) which can be life threatening. Tell your doctor if you ever had pancreatitis, gallstones, and history of alcohol intake. 
  • If you experience severe joint pain or allergic reactions (skin rash, swelling of the face, lips, tongue and throat which causes difficulty in breathing), stop taking the medicine and inform your doctor.

Frequently asked questions FOR KOMBIGLYZE

Saxagliptin

Q. Does saxagliptin/ Kombiglyze cause diarrhea?
Kombiglyze is trade name for the combination of medicines saxagliptin and metformin. Saxagliptin/ Kombiglyze may cause diarrhea
Q. Does saxagliptin/Onglyza/ Kombiglyze cause cancer?
Onglyza is a trade name for medicine saxagliptin. Kombiglyze is trade name for the combination of medicines saxagliptin and metformin. Saxagliptin/Onglyza/ Kombiglyze has neither reported to cause any cancer, nor has any potential to cause cancer.
Q. Does saxagliptin/Kombiglyze cause constipation?
Kombiglyze is trade name for the combination of medicines saxagliptin and metformin.. Saxagliptin/Kombiglyze does not cause constipation
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Q. Does Onglyza contain metformin?
No. It only contains saxagliptin as an active drug
Q. Does Kombiglyze cause weight loss (reduction)?
Kombiglyze is trade name for the combination of medicines saxagliptin and metformin. Weight loss is one of the side effect of Kombiglyze; the metformin component present in Kombiglyze may be responsible for the same. Please note, Kombiglyze is not a weight-loss drug
Q. Does Onglyza have a generic?
Onglyza is the trade name of the active drug saxagliptin. Saxagliptin is not available in a generic form
Q. Does saxagliptin/Onglyza cause weight loss/ weight gain?
Onglyza is the trade name for saxagliptin. Saxagliptin/Onglyza does not cause weight loss/reduction. Saxagliptin/ Onglyza does not cause any apparent change in body weight
Q. Does saxagliptin/Kombiglyze cause hair loss?
Kombiglyze is trade name for the combination of medicines saxagliptin and metformin. Saxagliptin/Kombiglyze does not cause hair loss

Metformin

Q. What is metformin?
Metformin is an antidiabetic drug used to control high blood sugar levels in newly-diagnosed type 2 diabetes patients, along with modifications in diet and exercise.
Q. Is metformin safe?
Metformin is generally safe if taken at prescribed doses for the prescribed duration as advised by your doctor.
Q. Can I take metformin forever?
Metformin should be taken at prescribed doses for the prescribed duration as advised by your doctor.
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Q. Is metformin a sulfonylurea?
No, metformin is not a sulfonylurea.
Q. Is metformin a steroid?
No, metformin is not a steroid.
Q. Is metformin taken before meals?
It is preferred to take metformin with food.
Q. Is metformin safe in pregnancy or contraindicated?
No relevant data is available for use of metformin in pregnancy. Animal studies do not indicate any harmful effect. Please consult your doctor before taking metformin during pregnancy.
Q. Is metformin safe for weight loss?
Metformin is not indicated for weight loss.
Q. Is metformin good for fatty liver?
Metformin is not indicated for the treatment of fatty liver.
Q. Can I take metformin without food?
It is better to take metformin with food.
Q. Can I take metformin with alcohol?
Taking metformin with alcohol may cause lactic acidosis and you may experience malaise, respiratory distress, slow or irregular heartbeat, somnolence, abdominal upset, or other unusual symptoms. It is better to avoid taking alcohol while you are taking metformin.
Q. Can I take metformin with atorvastatin?
Yes, metformin can be taken with atorvastatin. No drug-drug interactions have been reported between the two. However, interactions can occur. Please consult your doctor before taking the two medicines together.<br> Always consult your doctor before using the two medicines together.
Q. Can I take metformin with phentermine?
Metformin can be taken with phentermine. No interactions have been reported between them. However, it may exist. Always consult your doctor before using the two medicines together.
Q. Can I take metformin with food?
Yes, metformin can be taken with food. It is preferred to take metformin with food.
Q. Can I take metformin with levothyroxine?
Metformin can be taken with levothyroxine. No interactions have been reported between metformin and levothyroxine. However, it may exist. Always consult your doctor before using the two medicines together.
Q. Can I take metformin with prednisone or prednisolone?
Always consult your doctor before taking metformin with prednisone as it may decreases the effect of metformin and high blood sugar levels have been seen in some patients and it is recommended to monitor the blood glucose level regularly.
Q. Can I take metformin with metoprolol?
Use of metformin and metoprolol should be avoided at the same time. If you are taking these two medicines together you may experience confusion, dizziness, faster heart beat, tremors (shaking) and increased sweating. Please consult your doctor before taking them together.
Q. Does metformin clear acne?
Metformin is not indicated for clearing acne.
Q. Does metformin affect your period?
No, metformin does not affect your periods. In case you experience abnormalities in your periods while taking metformin, please consult your doctor.
Q. Does metformin cause hair loss?
No, hair loss has not been reported with metformin. In case you experience hair loss while taking metformin, please consult your doctor.
Q. Does metformin cause weight gain?
No, weight gain has not been reported with metformin.
Q. Does metformin reduce weight?
Yes, metformin may reduce weight. Please consult your doctor, if there is an unexpected weight loss along with tiredness and feeling of being sick.
Q. Does metformin cause hypoglycemia?
Metformin alone does not cause hypoglycemia, although caution is needed when taking it along with other anti-diabetic drugs like sulfonylureas and insulin.
Q. Does metformin cause constipation?
Constipation has not been reported with metformin. Please consult your doctor if you experience constipation while taking metformin.
Q. Does metformin increase blood pressure?
No metformin does not cause an increase in blood pressure. But caution should be taken when taking any medicines for the treatment of high blood pressure.
Q. Can I take metformin for polycystic ovarian syndrome (PCOS)?
Metformin is not a first line treatment of choice in the management of polycystic ovarian syndrome (PCOS). the first aim for women with PCOS who are overweight is to make lifestyle changes with a combination of diet and exercise in order to lose weight and improve ovarian function. Please consult your doctor before taking metformin for PCOS.
Q. Can I take metformin for weight loss?
No, metformin is not indicated for weight loss although it may reduce the weight of obese patients with type 2 diabetes mellitus.
Q. How long can I take metformin for polycystic ovarian syndrome (PCOS)?
Metformin should be taken at prescribed doses for the prescribed duration only as advised by your doctor. Also refer the question above.
Q. Can I take metformin for polycystic ovarian syndrome (PCOS) while pregnant?
No relevant data is available for use of metformin in pregnancy. Animal studies do not indicate any harmful effect. Please consult your doctor before taking metformin during pregnancy. Also refer the question above.
Q. How long can I take metformin for?
Metformin should be taken at prescribed doses for the prescribed duration only as advised by your doctor.
Q. Is metformin an insulin?
No, metformin is not an insulin.
Q. Is metformin a banned drug?
No, metformin is not a banned drug.
Q. Is metformin a birth control pill?
No, metformin is not a birth control pill.
Q. Is metformin a statin?
No, metformin is not a statin.

TOP MEDICINES PRESCRIBED WITH KOMBIGLYZE 5MG/1000MG TABLET XR

WHAT OUR USERS ARE SAYING ABOUT KOMBIGLYZE 5MG/1000MG TABLET XR

How effective is this medicine?

Effective
60%
Can't say
30%
Moderately effective
10%

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Yes
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Content on this page was last updated on 20 April, 2017, by Dr. Varun Gupta (MD Pharmacology)