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Last updated
07 Jun 2022 | 04:02 PM (IST)

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Kadcyla 100mg Injection

Prescription Required
Storage
Store in a refrigerator (2 - 8°C). Do not freeze.

Product introduction

Kadcyla 100mg Injection is used in the treatment of early as well as metastatic breast cancer. It is used to treat certain types of breast cancer (human epidermal growth factor receptor 2, HER-2) which have spread to other organs and have not responded to other cancer medicines.

Kadcyla 100mg Injection is given as an injection by a qualified medical professional. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.


The most common side effects of this medicine include tiredness, nausea, musculoskeletal (bone, muscle or joint) pain, and bleeding. This medicine may reduce the number of blood cells (decrease red blood and white blood cells) in your blood, thereby, increasing the susceptibility to infections. Regular blood tests are required to check your blood cells along with heart, liver, and blood uric acid levels.


Before taking it, tell your doctor if you have heart disease, liver, or kidney problems or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your healthcare team know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy.


"There is a Patient Support Program / Patient Assistance Program available in India for this medicine, being managed by Tata 1mg. Please contact your prescribing doctor to know more about the same. You may also call on (1800-102-1618) for more details."


Uses of Kadcyla Injection

Benefits of Kadcyla Injection

In Early Breast cancer

Kadcyla 100mg Injection helps to treat initial stages of breast cancer and it may be used alone or in combination with other medicines or treatment modalities like chemotherapy. It relieves the symptoms of breast cancer such as breast lumps, bloody discharge from nipples or changes in the shape or texture of the breast. Kadcyla 100mg Injection kills or stops the growth of cancer cells and also prevents the multiplication of cancer cells. Discuss with your doctor if any of the side effects bother you.

In Metastatic breast cancer

Kadcyla 100mg Injection helps to treat breast cancer and it may be used alone or in combination with other medicines or treatment modalities like chemotherapy. This medicine is used when other medicines have not shown significant improvement and the cancer has spread to other parts as well. It relieves the symptoms of breast cancer such as breast lumps, bloody discharge from nipples or changes in the shape or texture of the breast. Kadcyla 100mg Injection kills or stops the growth of cancer cells and also prevents the multiplication of cancer cells. Discuss with your doctor if any of the side effects bother you.

Side effects of Kadcyla Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Kadcyla

  • Tiredness
  • Nausea
  • Musculoskeletal (bone, muscle or joint) pain
  • Bleeding
  • Low blood platelets
  • Headache
  • Liver disorder
  • Constipation
  • Nosebleeds

How to use Kadcyla Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Kadcyla Injection works

Kadcyla 100mg Injection is an anti-cancer medicine. It binds to HER2 receptors on breast cancer cells and flags the cancer cells for destruction by the body's immune system. It also goes into the cancer cells to release a chemotherapy medicine (emtansine) and stop them from growing and dividing.

Safety advice

Alcohol
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Kadcyla 100mg Injection. Please consult your doctor.
Pregnancy
CONSULT YOUR DOCTOR
Kadcyla 100mg Injection is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
Breast feeding
UNSAFE
Kadcyla 100mg Injection is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
Driving
SAFE
Kadcyla 100mg Injection does not usually affect your ability to drive.
Kidney
CONSULT YOUR DOCTOR
There is limited information available on the use of Kadcyla 100mg Injection in patients with kidney disease. Please consult your doctor.
Liver
CAUTION
Kadcyla 100mg Injection should be used with caution in patients with severe liver disease. Dose adjustment of Kadcyla 100mg Injection may be needed. Please consult your doctor.

What if you forget to take Kadcyla Injection?

If you miss a dose of Kadcyla 100mg Injection, please consult your doctor.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.
No substitutes found for this medicine

Quick tips

  • Kadcyla 100mg Injection is given via a drip into a vein (intravenous infusion) under the supervision of a doctor.
  • Do not skip any dose and complete the course as suggested by your doctor.
  • Your doctor may check your liver function before starting treatment and regularly thereafter. Inform your doctor if you notice yellowing of eyes or skin, dark urine, or stomach pain.
  • Women who could get pregnant should use a reliable method of contraception to prevent pregnancy while taking this medicine.
  • Regular monitoring of heart function (tests like echocardiogram) and blood tests to monitor the level of blood cells may be advised before starting treatment and regularly during treatment with Kadcyla 100mg Injection.

Fact Box

Chemical Class
Monoclonal antibody (mAb)
Habit Forming
No
Therapeutic Class
ANTI NEOPLASTICS
Action Class
HER2/neu (ErbB2) Inhibitor- Monoclonal antibody

Patient concerns

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BREAST CANCER , PET REPORT SAYS INFECTION IN SKELETON.
Dr. Sanjay Singh Rai
Medical Oncology and Hematology
Metastatic breast cancer, send me previous treatment details
Breast cancer With lympnode and few skeletal metastatic
Dr. Vijay Sharnangat
Medical Oncology and Hematology
What a bout ER PR AND HER2
arrow

User feedback


FAQs

Q. What is the use of Kadcyla 100mg Injection?

Kadcyla 100mg Injection is used to treat HER2-positive breast cancer that has spread to other parts of the body (metastatic breast cancer) after prior treatment with trastuzumab and a taxane.

Q. How is Kadcyla 100mg Injection different?

Kadcyla 100mg Injection is a conjugate of the HER2 directed trastuzumab and a highly toxic microtubule-targeted drug (emtansine). Thus it is made up of 2 cancer-fighting agents in 1 medicine- The monoclonal antibody trastuzumab and a chemotherapy emtansine. Kadcyla 100mg Injection brings chemotherapy medicine (emtansine) into HER2-positive cells and kills them. It is designed to cause less harm to normal cells.

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Disclaimer:

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

  1. Kadcyla. Ado-trastuzumab emtansine. [Accessed 26 Mar. 2019] (online) Available from:External Link
  2. Ado-trastuzumab emtansine. South San Francisco, CA: Genentech, Inc.; [Accessed 26 Mar. 2019] (online) Available from:External Link
  3. Trastuzumab emtansine. Emil-Barell-Strasse: Roche Registration GmbH; 2013 [revised 17 Sep. 2018]. [Accessed 26 Mar. 2019] (online) Available from:External Link

Manufacturer/Marketer address

1503, 15th Floor, ‘The Capital’, Plot no. C-70, Behind ICICI Bank, BKC, Bandra (E) , Mumbai 400051
Country of origin: United states
Expires on or after: November, 2022

A licensed vendor partner from your nearest location will deliver Kadcyla 100mg Injection. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.
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1 Injection in 1 vial
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