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IWATA 500MG TABLET

Tablet
Rs.57.37for 1 strip(s) (10 tablets each)
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Composition FOR IWATA 500mg tablet

Sulfasalazine(500mg)

food interaction for IWATA tablet

alcohol interaction for IWATA tablet

pregnancy interaction for IWATA tablet

lactation interaction for IWATA tablet

medicine interaction for IWATA tablet

food
alcohol
pregnancy
lactation
medicine
It is better to take Iwata 500mg tablet with food.
Interaction with alcohol is unknown. Please consult your doctor.
Iwata 500mg tablet is probably safe to use during pregnancy.
Animal studies have shown low or no adverse effect on the foetus, however, there are limited human studies. Please consult your doctor.
PROBABLY SAFE
Unknown. Human and animal studies are not available. Please consult your doctor.
  • SERIOUS INTERACTION
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  • SALT INFORMATION FOR IWATA 500mg tablet

    Sulfasalazine(500mg)

    Iwata tablet uses

    Iwata 500mg tablet is used in the treatment of rheumatoid arthritis, ulcerative colitis, crohn’s disease and ankylosing spondylitis.

    How iwata tablet works

    Iwata 500mg tablet blocks the action of certain chemical messengers that are responsible for inflammation, swelling, and redness associated with the certain autoimmune diseases. It dampens down the underlying disease process, rather than simply treating the disease.

    Common side effects of iwata tablet

    Nausea, Headache, Skin rash, Loss of appetite, Increased body temperature

    SUBSTITUTES FOR IWATA tablet

    4 Substitutes
    4 Substitutes
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    Expert advice FOR IWATA tablet

    • Inform your doctor if you ever had any form of drug allergy. 
    • Inform your doctor if you are pregnant or planning to conceive or breastfeeding. 
    • Inform your doctor if you have a fertility problem. Sulfasalazine may cause a fall in sperm count, so may lead to a temporary decrease in male fertility, but can be reversed if treatment is stopped.
    • Inform your doctor if you are suffering from any blood disease e.g. G6PD deficiency. 
    • Your doctor may ask to get some blood test before you start treatment and also during the course of treatment.
    • You may have to wait for 6 to 12 weeks to get the full effect.
    • You may experience loss of appetite and nausea when treatment is started.
    • Your urine may change color (to orange) but there is nothing to worry about.
    • Drink plenty of water while on treatment with Sulfasalazine. This helps to prevent kidney stone and kidney damage.
    • You should tell your doctor about all medicines you are taking or plan to take. This includes ayurvedic or herbal/naturopathic medicines.
    • Inform your doctor right away if you have any of the following problems: a sore throat or fever or any sign of infection.

    Frequently asked questions FOR IWATA 500mg tablet

    Sulfasalazine

    Q. Is Sulfasalazine a DMARDs?
    Yes, Sulfasalazine is a DMARDs (Disease-Modifying Antirheumatic Drugs). It prevents joint damage and preserves joint mobility.
    Q. Can I use Sulfasalazine 1gram BD?
    Yes, Sulfasalazine can be used as 1gm BD (twice daily) if you have severe disease.
    Q. How is Sulfasalazine metabolized?
    Sulfasalazine is metabolized in the colon by the bacterial enzyme azoreductase to sulfapyridine and 5 aminosalicylic acid (5-ASA).
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    Q. How long does Sulfasalazine take to produce the effect?
    Sulfasalazine does not work right away. It will take about 6 to 12 weeks to get the full effect.
    Q. Where is sulfasalazine absorbed?
    Sulfasalazine is absorbed in the intestine (jejunum and colon). In the colon, it breaks down to sulfapyridine and 5 aminosalicylic acid (5-ASA).
    Q. Can I use Sulfasalazine with hepatitis B?
    Yes, Sulfasalazine is relatively safe in hepatitis B infection.
    Q. Can I use Sulfasalazine in hepatitis C?
    Sulfasalazine should not be used in hepatitis C patients with bad prognosis.
    Q. Sulfasalazine for alopecia areata?
    Sulfasalazine is not approved for treatment of alopecia areata.
    Q. Sulfasalazine for gout?
    Sulfasalazine is not approved for treatment of gout.
    Q. Sulfasalazine for IBS (irritable bowel syndrome)?
    Sulfasalazine is not approved for treatment of irritable bowel syndrome (IBS).
    Q. Sulfasalazine for IBD(inflammatory bowel disease)?
    Yes, Sulfasalazine is used in the treatment of inflammatory bowel disease (IBD).
    Q. Sulfasalazine for psoriatic arthritis?
    Sulfasalazine is a DMARD that may be effective for the joint pain and skin lesions associated with psoriatic arthritis.
    Q. Sulfasalazine for psoriasis?
    Sulfasalazine is not approved for psoriasis.
    Q. Can I use Sulfasalazine with vitamin c?
    Yes, Sulfasalazine can be used with vitamin c.
    Q. Can I use Sulfasalazine with vitamin d?
    Yes, Sulfasalazine can be used with vitamin d.
    Q. Sulfasalazine vs mesalamine?
    Mesalamine and Sulfasalazine are both used in the treatment of ulcerative colitis. Sulfasalazine having fewer side effects as compared to mesalamine.
    Q. Sulfasalazine vs balsalazide?
    Balsalazide has a better tolerability than Sulfasalazine in patients with ulcerative colitis.
    Q. Sulfasalazine with folic acid?
    Sulfasalazine inhibits the absorption and metabolism of folic acid.which may cause folic acid deficiency. This can result in serious blood disorders (e.g., macrocytosis and pancytopenia). This can be normalized by administration of folic acid or folinic acid (leucovorin).
    Q. Sulfasalazine interaction with methotrexate?
    Coadministration of Sulfasalazine and methotrexate do not alter the pharmacokinetic disposition of the drugs. It may increase the incidence of gastrointestinal adverse events, especially nausea.
    Q. Sulfasalazine with meloxicam?
    Meloxicam and Sulfasalazine cause kidney problem if given together.
    Q. Sulfasalazine with antibiotics?
    People who are allergic to sulfa drugs antibiotics like cotrimoxazole, sulfisoxazole etc, may have a cross reaction to Sulfasalazine and should therefore not take it.
    Q. Sulfasalazine with prednisone?
    Sulfasalazine can be given in conjunction with steroids (prednisone) as part of an intensive management regime during the severe attack of rheumatoid arthritis.
    Q. Sulfasalazine with adalimumab?
    Adalimumab can be used with Sulfasalazine in the treatment of moderate to severe, active rheumatoid arthritis in adult patients when the response to disease-modifying antirheumatic drugs (DMARDs) is inadequate.
    Q. Sulfasalazine with the sulfa allergy?
    Patients with sulfa drug allergy should avoid Sulfasalazine.
    Q. Sulfasalazine with naproxen?
    Sulfasalazine is used in the treatment of rheumatoid arthritis who has failed to respond to non-steroidal anti-inflammatory drugs (NSAIDs) e.g naproxen.
    Q. Sulfasalazine with ibuprofen?
    Sulfasalazine is used in the treatment of rheumatoid arthritis who has failed to respond to non-steroidal anti-inflammatory drugs (NSAIDs) e.g ibuprofen.
    Q. Sulfasalazine with methotrexate side effects?
    Taking Sulfasalazine and methotrexate together may increase the incidence of gastrointestinal adverse events, especially nausea.
    Q. Sulfasalazine with hydroxychloroquine?
    Sulfasalazine and hydroxychloroquine combination have shown better and faster response in rheumatoid arthritis.
    Q. Allergic to Sulfasalazine?
    You should not take Sulfasalazine, if you are allergic to Sulfasalazine.
    Q. Is Sulfasalazine a prodrug?
    Yes, Sulfasalazine is a prodrug. It gets converted into sulfonamide (sulfapyridine) and 5 aminosalicylic acid (5-ASA) in the body.
    Q. Is Sulfasalazine a sulfa drug?
    Yes, Sulfasalazine is a sulfa drug because it contains sulfonamide (sulfapyridine) as active ingredients.
    Q. Is Sulfasalazine an antibiotic?
    Sulfasalazine is a combination of antibiotic sulfapyridine and 5 aminosalicylic acid, mainly used in inflammatory bowel disease and rheumatoid arthritis.
    Q. Is Sulfasalazine enteric coated?
    Some formulation of Sulfasalazine may be available as enteric-coated. Enteric coating is done to prevent the tablet destruction by stomach acid.
    Q. Sulfasalazine causes weight loss?
    Yes, Sulfasalazine can cause loss of appetite which may lead to loss of weight.
    Q. Can Sulfasalazine cause rash?
    Yes, Sulfasalazine can cause the rash as a side effect.
    Q. What is the Sulfasalazine drug class?
    Sulfasalazine belongs to sulfonamide drug class.
    Q. What is Sulfasalazine delayed-release tablets?
    Sulfasalazine delayed release tablets are the enteric coated tablets, which prevent the disintegration of the drug when they come in contact with stomach acid.
    Q. Sulfasalazine cause insomnia?
    Yes, Sulfasalazine can cause insomnia as a side effect.
    Q. Sulfasalazine flu-like symptoms?
    Sulfasalazine can cause flu-like symptoms like aching of joints, fever, headache, sore throat, rashes.
    Q. Sulfasalazine for ulcerative colitis?
    Ulcerative colitis is an inflammatory bowel disease. Sulfasalazine releases 5 aminosalicylic acid which decreases inflammation of the intestines and thus helpful in ulcerative colitis.
    Q. Sulfasalazine for Crohn's disease?
    Crohn's disease is an inflammatory bowel disease. Sulfasalazine releases 5 aminosalicylic acid which decreases inflammation of the intestines and thus helpful in Crohn's disease.
    Q. Sulfasalazine in cancer patients?
    Sulfasalazine is not approved for treatment of cancer.
    Q. Why does Sulfasalazine cause blood disorders?
    Sulfasalazine inhibits the absorption and metabolism of folic acid. Which may cause folic acid deficiency. This can result in serious blood disorders (e.g., macrocytosis and pancytopenia).
    Q. Why does Sulfasalazine cause a sore throat?
    Sulfasalazine suppresses the immune system which can manifest with the sign of infections like a sore throat or fever.
    Q. What does Sulfasalazine contain?
    Sulfasalazine contains sulfonamide (sulfapyridine) and 5 aminosalicylic acid (5-ASA) as active ingredients.
    Q. Side effects of stopping sulfasalazine?
    If Sulfasalazine is stopped, patient can experience withdrawal symptoms like depression, pain, stress, anxiety, back pain, and muscle spasticity.
    Q. Sulfasalazine withdrawal?
    Sulfasalazine withdrawal can cause depression, pain, stress, anxiety, back pain and muscle spasticity.

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    Content on this page was last updated on 08 March, 2017, by Dr. Varun Gupta (MD Pharmacology)