Medicine Overview of Iwata Tablet
Nausea, Headache, Skin rash, Loss of appetite, Increased body temperature.
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Iwata 500mg Tablet is to be taken with food.
Iwata 500mg Tablet blocks the action of certain chemical messengers that are responsible for inflammation, swelling and redness associated with certain autoimmune diseases.
It suppresses the underlying disease process, rather than simply treating the disease.
In Depth Information on Iwata Tablet
You have been prescribed Iwata to control the symptoms and slow down the progression of inflammatory bowel disease or rheumatoid arthritis.
You may have to wait for 6 to 12 weeks to get the full effect.
Drink plenty of water while on Iwata. This will prevent kidney stone and kidney damage.
You may experience loss of appetite and nausea on starting Iwata.
Your urine may change color (to orange). Do not worry if that happens.
Avoid contact with people who have cold, flu or other contagious illness. Notify your doctor if you have any signs of infection such as a fever or sore throat.
Inform your doctor if you ever had any form of drug allergy.
- Inform your doctor if you are pregnant or planning to conceive or breastfeeding.
- Inform your doctor if you are suffering from any blood disease e.g. G6PD deficiency.
Iwata Tablet related warnings
Interaction with alcohol is unknown. Please consult your doctor.
Iwata 500mg Tablet is probably safe to use during pregnancy.
Animal studies have shown low or no adverse effect on the foetus, however, there are limited human studies. Please consult your doctor.
Iwata 500mg Tablet is probably unsafe to use during lactation.
Limited human data suggest that the drug could represent a significant risk to the baby.
Iwata 500mg Tablet does not usually affect your ability to drive.
Iwata 500mg Tablet should be used with caution in patients with kidney disease. Dose adjustment of Iwata 500mg Tablet may be needed. Please consult your doctor.
Regular monitoring of kidney function tests is advisable while you are taking this medicine.
Iwata 500mg Tablet is probably unsafe to use in patients with liver disease and should be avoided. Please consult your doctor.
If you miss a dose of Iwata 500mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Frequently asked questions about Iwata Tablet
Yes, Iwata is a DMARDs (Disease-Modifying Antirheumatic Drugs). It prevents joint damage and preserves joint mobility.
Q. Can I use Iwata 1gram BD?
Yes, Iwata can be used as 1gm BD (twice daily) if you have severe disease.
Q. How is Iwata metabolized?
Iwata is metabolized in the colon by the bacterial enzyme azoreductase to sulfapyridine and 5 aminosalicylic acid (5-ASA).
Q. How long does Iwata take to produce the effect?
Iwata does not work right away. It will take about 6 to 12 weeks to get the full effect.
Q. Where is sulfasalazine absorbed?
Iwata is absorbed in the intestine (jejunum and colon). In the colon, it breaks down to sulfapyridine and 5 aminosalicylic acid (5-ASA).
Q. Can I use Iwata with hepatitis B?
Yes, Iwata is relatively safe in hepatitis B infection.
Q. Can I use Iwata in hepatitis C?
Iwata should not be used in hepatitis C patients with bad prognosis.
Q. Iwata for alopecia areata?
Iwata is not approved for treatment of alopecia areata.
Iwata is not approved for treatment of gout.
Q. Iwata for IBS (irritable bowel syndrome)?
Iwata is not approved for treatment of irritable bowel syndrome (IBS).
Q. Iwata for IBD(inflammatory bowel disease)?
Yes, Iwata is used in the treatment of inflammatory bowel disease (IBD).
Q. Iwata for psoriatic arthritis?
Iwata is a DMARD that may be effective for the joint pain and skin lesions associated with psoriatic arthritis.
Iwata is not approved for psoriasis.
Q. Can I use Iwata with vitamin c?
Yes, Iwata can be used with vitamin c.
Q. Can I use Iwata with vitamin d?
Yes, Iwata can be used with vitamin d.
Mesalamine and Iwata are both used in the treatment of ulcerative colitis. Iwata having fewer side effects as compared to mesalamine.
Balsalazide has a better tolerability than Iwata in patients with ulcerative colitis.
Q. Iwata with folic acid?
Iwata inhibits the absorption and metabolism of folic acid.which may cause folic acid deficiency. This can result in serious blood disorders (e.g., macrocytosis and pancytopenia). This can be normalized by administration of folic acid or folinic acid (leucovorin).
Q. Iwata interaction with methotrexate?
Coadministration of Iwata and methotrexate do not alter the pharmacokinetic disposition of the drugs. It may increase the incidence of gastrointestinal adverse events, especially nausea.
Meloxicam and Iwata cause kidney problem if given together.
Q. Iwata with antibiotics?
People who are allergic to sulfa drugs antibiotics like cotrimoxazole, sulfisoxazole etc, may have a cross reaction to Iwata and should therefore not take it.
Q. Iwata with prednisone?
Iwata can be given in conjunction with steroids (prednisone) as part of an intensive management regime during the severe attack of rheumatoid arthritis.
Q. Iwata with adalimumab?
Adalimumab can be used with Iwata in the treatment of moderate to severe, active rheumatoid arthritis in adult patients when the response to disease-modifying antirheumatic drugs (DMARDs) is inadequate.
Q. Iwata with the sulfa allergy?
Patients with sulfa drug allergy should avoid Iwata.
Iwata is used in the treatment of rheumatoid arthritis who has failed to respond to non-steroidal anti-inflammatory drugs (NSAIDs) e.g naproxen.
Iwata is used in the treatment of rheumatoid arthritis who has failed to respond to non-steroidal anti-inflammatory drugs (NSAIDs) e.g ibuprofen.
Q. Iwata with methotrexate side effects?
Taking Iwata and methotrexate together may increase the incidence of gastrointestinal adverse events, especially nausea.
Q. Iwata with hydroxychloroquine?
Iwata and hydroxychloroquine combination have shown better and faster response in rheumatoid arthritis.
You should not take Iwata, if you are allergic to Iwata.
Yes, Iwata is a prodrug. It gets converted into sulfonamide (sulfapyridine) and 5 aminosalicylic acid (5-ASA) in the body.
Q. Is Iwata a sulfa drug?
Yes, Iwata is a sulfa drug because it contains sulfonamide (sulfapyridine) as active ingredients.
Q. Is Iwata an antibiotic?
Iwata is a combination of antibiotic sulfapyridine and 5 aminosalicylic acid, mainly used in inflammatory bowel disease and rheumatoid arthritis.
Q. Is Iwata enteric coated?
Some formulation of Iwata may be available as enteric-coated. Enteric coating is done to prevent the tablet destruction by stomach acid.
Q. Iwata causes weight loss?
Yes, Iwata can cause loss of appetite which may lead to loss of weight.
Yes, Iwata can cause the rash as a side effect.
Q. What is the Iwata drug class?
Iwata belongs to sulfonamide drug class.
Q. What is Iwata delayed-release tablets?
Iwata delayed release tablets are the enteric coated tablets, which prevent the disintegration of the drug when they come in contact with stomach acid.
Yes, Iwata can cause insomnia as a side effect.
Q. Iwata flu-like symptoms?
Iwata can cause flu-like symptoms like aching of joints, fever, headache, sore throat, rashes.
Q. Iwata for ulcerative colitis?
Ulcerative colitis is an inflammatory bowel disease. Iwata releases 5 aminosalicylic acid which decreases inflammation of the intestines and thus helpful in ulcerative colitis.
Q. Iwata for Crohn's disease?
Crohn's disease is an inflammatory bowel disease. Iwata releases 5 aminosalicylic acid which decreases inflammation of the intestines and thus helpful in Crohn's disease.
Q. Iwata in cancer patients?
Iwata is not approved for treatment of cancer.
Q. Why does Iwata cause blood disorders?
Iwata inhibits the absorption and metabolism of folic acid. Which may cause folic acid deficiency. This can result in serious blood disorders (e.g., macrocytosis and pancytopenia).
Q. Why does Iwata cause a sore throat?
Iwata suppresses the immune system which can manifest with the sign of infections like a sore throat or fever.
Q. What does Iwata contain?
Iwata contains sulfonamide (sulfapyridine) and 5 aminosalicylic acid (5-ASA) as active ingredients.
Q. Side effects of stopping sulfasalazine?
If Iwata is stopped, patient can experience withdrawal symptoms like depression, pain, stress, anxiety, back pain, and muscle spasticity.
Iwata withdrawal can cause depression, pain, stress, anxiety, back pain and muscle spasticity.
Severely interacts with other drugs like
Taking Iwata with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
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