Iwata 500mg Tablet

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Cadila Pharmaceuticals Ltd

Composition for Iwata 500mg Tablet

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57.37
₹5.74/Tablet
10 tablets in 1 strip
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Medicine Overview of Iwata Tablet

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Uses of Iwata Tablet

Iwata 500mg Tablet is used in the treatment of rheumatoid arthritis, ulcerative colitis, Crohn’s disease and ankylosing spondylitis.
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Side effects of Iwata Tablet

Common

Nausea, Headache, Skin rash, Loss of appetite, Increased body temperature.

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How to use Iwata Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. It is better to take Iwata 500mg Tablet with food.

How Iwata Tablet works

Iwata 500mg tablet blocks the action of certain chemical messengers that are responsible for inflammation, swelling and redness associated with certain autoimmune diseases. It suppresses the underlying disease process, rather than simply treating the disease.

In Depth Information on Iwata Tablet

Expert advice for Iwata Tablet

  • Inform your doctor if you ever had any form of drug allergy. 
  • Inform your doctor if you are pregnant or planning to conceive or breastfeeding. 
  • Inform your doctor if you have a fertility problem. Iwata may cause a fall in sperm count, so may lead to a temporary decrease in male fertility, but can be reversed if treatment is stopped.
  • Inform your doctor if you are suffering from any blood disease e.g. G6PD deficiency. 
  • Your doctor may ask to get some blood test before you start treatment and also during the course of treatment.
  • You may have to wait for 6 to 12 weeks to get the full effect.
  • You may experience loss of appetite and nausea when treatment is started.
  • Your urine may change color (to orange) but there is nothing to worry about.
  • Drink plenty of water while on treatment with Iwata. This helps to prevent kidney stone and kidney damage.
  • You should tell your doctor about all medicines you are taking or plan to take. This includes ayurvedic or herbal/naturopathic medicines.
  • Inform your doctor right away if you have any of the following problems: a sore throat or fever or any sign of infection.
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Warnings
Special precautions for Iwata 500mg Tablet
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Alcohol
Interaction with alcohol is unknown. Please consult your doctor.
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Pregnancy
PROBABLY SAFE
Iwata 500mg Tablet is probably safe to use during pregnancy.

Animal studies have shown low or no adverse effect on the foetus, however, there are limited human studies. Please consult your doctor.
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Lactation
CAUTION
Iwata 500mg Tablet is probably usafe to use during lactation
. Limited human data suggests that the drug could represent a significant risk to the baby.
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Driving
SAFE
Iwata 500mg Tablet does not usually affect your ability to drive.
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Kidney
CAUTION
Iwata 500mg Tablet should be used with caution in patients with kidney disease. Dose adjustment of Iwata 500mg Tablet may be needed. Please consult your doctor.

Regular monitoring of kidney function tests is advisable while you are taking this medicine.
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Liver
UNSAFE
Iwata 500mg Tablet is probably unsafe to use in patients wit
h liver disease and should be avoided. Please consult your doctor.
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Severely interacts with other drugs like
Captomer 50mg Tablet, Autorin 50mg Tablet, Azoprine 50mg Tablet, Thiopress 50mg Tablet

Missed Dosageuses

If you miss a dose of Sulfasalazine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

Patient Concerns

Frequently asked questions for Iwata 500mg Tablet

Frequently asked questions for Sulfasalazine

Q. Is Iwata a DMARDs?
Yes, Iwata is a DMARDs (Disease-Modifying Antirheumatic Drugs). It prevents joint damage and preserves joint mobility.
Q. Can I use Iwata 1gram BD?
Yes, Iwata can be used as 1gm BD (twice daily) if you have severe disease.
Q. How is Iwata metabolized?
Iwata is metabolized in the colon by the bacterial enzyme azoreductase to sulfapyridine and 5 aminosalicylic acid (5-ASA).
Q. How long does Iwata take to produce the effect?
Iwata does not work right away. It will take about 6 to 12 weeks to get the full effect.
Q. Where is sulfasalazine absorbed?
Iwata is absorbed in the intestine (jejunum and colon). In the colon, it breaks down to sulfapyridine and 5 aminosalicylic acid (5-ASA).
Q. Can I use Iwata with hepatitis B?
Yes, Iwata is relatively safe in hepatitis B infection.
Q. Can I use Iwata in hepatitis C?
Iwata should not be used in hepatitis C patients with bad prognosis.
Q. Iwata for alopecia areata?
Iwata is not approved for treatment of alopecia areata.
Q. Iwata for gout?
Iwata is not approved for treatment of gout.
Q. Iwata for IBS (irritable bowel syndrome)?
Iwata is not approved for treatment of irritable bowel syndrome (IBS).
Q. Iwata for IBD(inflammatory bowel disease)?
Yes, Iwata is used in the treatment of inflammatory bowel disease (IBD).
Q. Iwata for psoriatic arthritis?
Iwata is a DMARD that may be effective for the joint pain and skin lesions associated with psoriatic arthritis.
Q. Iwata for psoriasis?
Iwata is not approved for psoriasis.
Q. Can I use Iwata with vitamin c?
Yes, Iwata can be used with vitamin c.
Q. Can I use Iwata with vitamin d?
Yes, Iwata can be used with vitamin d.
Q. Iwata vs mesalamine?
Mesalamine and Iwata are both used in the treatment of ulcerative colitis. Iwata having fewer side effects as compared to mesalamine.
Q. Iwata vs balsalazide?
Balsalazide has a better tolerability than Iwata in patients with ulcerative colitis.
Q. Iwata with folic acid?
Iwata inhibits the absorption and metabolism of folic acid.which may cause folic acid deficiency. This can result in serious blood disorders (e.g., macrocytosis and pancytopenia). This can be normalized by administration of folic acid or folinic acid (leucovorin).
Q. Iwata interaction with methotrexate?
Coadministration of Iwata and methotrexate do not alter the pharmacokinetic disposition of the drugs. It may increase the incidence of gastrointestinal adverse events, especially nausea.
Q. Iwata with meloxicam?
Meloxicam and Iwata cause kidney problem if given together.
Q. Iwata with antibiotics?
People who are allergic to sulfa drugs antibiotics like cotrimoxazole, sulfisoxazole etc, may have a cross reaction to Iwata and should therefore not take it.
Q. Iwata with prednisone?
Iwata can be given in conjunction with steroids (prednisone) as part of an intensive management regime during the severe attack of rheumatoid arthritis.
Q. Iwata with adalimumab?
Adalimumab can be used with Iwata in the treatment of moderate to severe, active rheumatoid arthritis in adult patients when the response to disease-modifying antirheumatic drugs (DMARDs) is inadequate.
Q. Iwata with the sulfa allergy?
Patients with sulfa drug allergy should avoid Iwata.
Q. Iwata with naproxen?
Iwata is used in the treatment of rheumatoid arthritis who has failed to respond to non-steroidal anti-inflammatory drugs (NSAIDs) e.g naproxen.
Q. Iwata with ibuprofen?
Iwata is used in the treatment of rheumatoid arthritis who has failed to respond to non-steroidal anti-inflammatory drugs (NSAIDs) e.g ibuprofen.
Q. Iwata with methotrexate side effects?
Taking Iwata and methotrexate together may increase the incidence of gastrointestinal adverse events, especially nausea.
Q. Iwata with hydroxychloroquine?
Iwata and hydroxychloroquine combination have shown better and faster response in rheumatoid arthritis.
Q. Allergic to Iwata?
You should not take Iwata, if you are allergic to Iwata.
Q. Is Iwata a prodrug?
Yes, Iwata is a prodrug. It gets converted into sulfonamide (sulfapyridine) and 5 aminosalicylic acid (5-ASA) in the body.
Q. Is Iwata a sulfa drug?
Yes, Iwata is a sulfa drug because it contains sulfonamide (sulfapyridine) as active ingredients.
Q. Is Iwata an antibiotic?
Iwata is a combination of antibiotic sulfapyridine and 5 aminosalicylic acid, mainly used in inflammatory bowel disease and rheumatoid arthritis.
Q. Is Iwata enteric coated?
Some formulation of Iwata may be available as enteric-coated. Enteric coating is done to prevent the tablet destruction by stomach acid.
Q. Iwata causes weight loss?
Yes, Iwata can cause loss of appetite which may lead to loss of weight.
Q. Can Iwata cause rash?
Yes, Iwata can cause the rash as a side effect.
Q. What is the Iwata drug class?
Iwata belongs to sulfonamide drug class.
Q. What is Iwata delayed-release tablets?
Iwata delayed release tablets are the enteric coated tablets, which prevent the disintegration of the drug when they come in contact with stomach acid.
Q. Iwata cause insomnia?
Yes, Iwata can cause insomnia as a side effect.
Q. Iwata flu-like symptoms?
Iwata can cause flu-like symptoms like aching of joints, fever, headache, sore throat, rashes.
Q. Iwata for ulcerative colitis?
Ulcerative colitis is an inflammatory bowel disease. Iwata releases 5 aminosalicylic acid which decreases inflammation of the intestines and thus helpful in ulcerative colitis.
Q. Iwata for Crohn's disease?
Crohn's disease is an inflammatory bowel disease. Iwata releases 5 aminosalicylic acid which decreases inflammation of the intestines and thus helpful in Crohn's disease.
Q. Iwata in cancer patients?
Iwata is not approved for treatment of cancer.
Q. Why does Iwata cause blood disorders?
Iwata inhibits the absorption and metabolism of folic acid. Which may cause folic acid deficiency. This can result in serious blood disorders (e.g., macrocytosis and pancytopenia).
Q. Why does Iwata cause a sore throat?
Iwata suppresses the immune system which can manifest with the sign of infections like a sore throat or fever.
Q. What does Iwata contain?
Iwata contains sulfonamide (sulfapyridine) and 5 aminosalicylic acid (5-ASA) as active ingredients.
Q. Side effects of stopping sulfasalazine?
If Iwata is stopped, patient can experience withdrawal symptoms like depression, pain, stress, anxiety, back pain, and muscle spasticity.
Q. Iwata withdrawal?
Iwata withdrawal can cause depression, pain, stress, anxiety, back pain and muscle spasticity.
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