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ISTAMET 50 MG/500 MG TABLET

Tablet
Rs.348for 1 strip(s) (15 tablets each)
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Composition FOR ISTAMET

Sitagliptin(50 mg),Metformin(500 mg)

food interaction for ISTAMET

alcohol interaction for ISTAMET

pregnancy interaction for ISTAMET

lactation interaction for ISTAMET

food
alcohol
pregnancy
lactation
It is better to take Istamet 50 mg/500 mg tablet with food.
Taking Sitagliptin with alcohol may affect blood glucose levels in patients with diabetes.
Taking metformin with alcohol may cause lactic acidosis and you may experience malaise, respiratory distress, slow or irregular heartbeat, somnolence, abdominal upset, or other unusual symptoms.
UNSAFE
Istamet 50 mg/500 mg tablet is probably safe to use during pregnancy.
Animal studies have shown low or no adverse effect on the foetus, however, there are limited human studies. Please consult your doctor.
PROBABLY SAFE
Unknown. Human and animal studies are not available. Please consult your doctor.

SALT INFORMATION FOR ISTAMET

Sitagliptin(50 mg)

Uses

Sitagliptin is used in the treatment of type 2 diabetes

How it works

Sitagliptin increase the amount of insulin released by the pancreas, which in turn lowers the blood glucose levels.

Common side effects

Headache, Upper respiratory tract infection, Hypoglycaemia (fall in blood sugar level) in combination with insulin or sulphonylurea, Nasopharyngitis
Metformin(500 mg)

Uses

Metformin is used in the treatment of type 2 diabetes and polycystic ovary syndrome (PCOS)

How it works

Metformin restores the body's ability to use insulin, lowering the blood sugar levels. Metformin also lowers the amount of glucose absorbed from food into the intestines and lowers the glucose production in the liver.

Common side effects

Nausea, Vomiting, Altered taste, Abdominal pain, Diarrhoea, Loss of appetite

COMMON DOSAGE FOR ISTAMET 50 MG/500 MG TABLET

Patients taking ISTAMET 50 MG/500 MG TABLET

  • 52%
    Twice A Day
  • 46%
    Once A Day
  • 1%
    Thrice A Day

SUBSTITUTES FOR ISTAMET

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Expert advice FOR ISTAMET

  • Type 2 diabetes can be controlled with a proper diet alone or a diet along with exercise. A planned diet and exercising are always important when you have diabetes, even when you are taking antidiabetic medicines.
  • Notify your doctor if you have or ever had:
    • A disease of the pancreas (such as pancreatitis).
    • Gallstones, alcohol dependency or very high levels of triglycerides (a form of fat found in blood) in your blood. These medical conditions can increase your chance of getting pancreatitis.
    • Type 1 diabetes.
    • Diabetic ketoacidosis (a complication of diabetes with high blood sugar, rapid weight loss, nausea or vomiting)
    • Any past or present kidney problems.
    • An allergic reaction to Sitagliptin
     

Frequently asked questions FOR ISTAMET

Sitagliptin

Q.

Is sitagliptin/ Januvia safe?
Sitagliptin/ Januvia is safe at the prescribed dose by the doctor. Patients should follow the advice of the doctor regarding its use

Q.

Is sitagliptin/ Januvia generic?
Sitagliptin is generic drug; Januvia is a brand name of sitagliptin

Q.

Is sitagliptin/ Januvia banned in India?
No. Sitagliptin is available in India

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Q.

Is sitagliptin better than vildagliptin?
Sitagliptin and vildagliptin belong to same class of drugs and are equally effective and safe in treatment of type 2 diabetes mellitus. Always consult your doctor for an alternative drug of choice that may strictly be required

Q.

Is sitagliptin FDA approved?
Yes. Sitagliptin is FDA approved

Q.

Is sitagliptin a statin/ insulin/ metformin?
No. Sitagliptin belongs to class of medications called dipeptidyl peptidase-4 (DPP-4) inhibitors and is a different drug than statin/insulin/metformin

Q.

Is sitagliptin/Januvia a blood thinner?
Sitagliptin/Januvia is specifically used for treatment of type 2 diabetes mellitus and not a blood thinner. Patients should follow the advice of the doctor regarding its use

Q.

Can I take Januvia with metformin/ insulin/ glipizide/ Victoza/ Lantus/ glyburide/ glimepiride/ Actos / Byetta/ Bydureon?
Sitagliptin can be taken in combination with other antidiabetic drugs, when prescribed by doctor. Always follow doctor’s advice regarding its use

Q.

Does sitagliptin cause weight loss/ constipation/ joint pain/ itching/ hypoglycemia/ pancreatitis/ cancer/ dry mouth?
Sitagliptin may cause weight loss, constipation, itching, hypoglycemia, joint pain and pancreatitis. It does not cause cancer or dry mouth. However, consult your doctor if you experience any of these side effects

Q.

Does Januvia make you sleepy?
No. Januvia does not make you sleepy. Patients should follow the advice of the doctor regarding its use.

Metformin

Q.

What is metformin?
Metformin is an antidiabetic drug used to control high blood sugar levels in newly-diagnosed type 2 diabetes patients, along with modifications in diet and exercise.

Q.

Is metformin safe?
Metformin is generally safe if taken at prescribed doses for the prescribed duration as advised by your doctor.

Q.

Can I take metformin forever?
Metformin should be taken at prescribed doses for the prescribed duration as advised by your doctor.

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Q.

Is metformin a sulfonylurea?
No, metformin is not a sulfonylurea.

Q.

Is metformin a steroid?
No, metformin is not a steroid.

Q.

Is metformin taken before meals?
It is preferred to take metformin with food.

Q.

Is metformin safe in pregnancy or contraindicated?
No relevant data is available for use of metformin in pregnancy. Animal studies do not indicate any harmful effect. Please consult your doctor before taking metformin during pregnancy.

Q.

Is metformin safe for weight loss?
Metformin is not indicated for weight loss.

Q.

Is metformin good for fatty liver?r
Metformin is not indicated for the treatment of fatty liver.

Q.

Can I take metformin without food?
It is better to take metformin with food.

Q.

Can I take metformin with alcohol?
Taking metformin with alcohol may cause lactic acidosis and you may experience malaise, respiratory distress, slow or irregular heartbeat, somnolence, abdominal upset, or other unusual symptom. It is better to avoid taking alcohol while you are taking metformin.

Q.

Can I take metformin with atorvastatin?
Yes, metformin can be taken with atorvastatin. There are no interactions defined between the two medicines. However, it does not mean it does not exist. Always consult your doctor before using the two medicines together.

Q.

Can I take metformin with phentermine?
Metformin can be taken with phentermine. No interactions have been reported between them. However, it may exist. Always consult your doctor before using the two medicines together.

Q.

Can I take metformin with food?
Yes, metformin can be taken with food. It is preferred to take metformin with food.

Q.

Can I take metformin with levothyroxine?
Metformin can be taken with levothyroxine. No interactions have been reported between metformin and levothyroxine. However, it may exist. Always consult your doctor before using the two medicines together.

Q.

Can I take metformin with prednisone or prednisolone?
Always consult your doctor before taking metformin with prednisone as it may decreases the effect of metformin and high blood sugar levels have been seen in some patients and it is recommended to monitor the blood glucose level regularly.

Q.

Can I take metformin with metoprolol?
Use of metformin and metoprolol should be avoided at the same time. If you are taking these two medicines together you may experience confusion, dizziness, faster heart beat, tremors (shaking) and increased sweating. Please consult your doctor before taking them together.

Q.

Does metformin clear acne?
Metformin is not indicated for clearing acne.

Q.

Does metformin affect your period?
No, metformin does not affect your periods. In case you experience abnormalities in your periods while taking metformin, please consult your doctor.

Q.

Does metformin cause hair loss?
No, hair loss has not been reported with metformin. In case you experience hair loss while taking metformin, please consult your doctor.

Q.

Does metformin cause weight gain?
No, weight gain has not been reported with metformin.

Q.

Does metformin reduce weight?
Yes, metformin may reduce weight. Please consult your doctor, if there is an unexpected weight loss along with tiredness and feeling of being sick.

Q.

Does metformin cause hypoglycemia?
Metformin alone does not cause hypoglycemia, although caution is needed when taking it along with other anti-diabetic drugs like sulfonylureas and insulin.

Q.

Does metformin cause constipation?
Constipation has not been reported with metformin. Please consult your doctor if you experience constipation while taking metformin.

Q.

Does metformin increase blood pressure?
No metformin does not cause an increase in blood pressure. But caution should be taken when taking any medicines for the treatment of high blood pressure.

Q.

Can I take metformin for polycystic ovarian syndrome (PCOS)?
Metformin is not a first line treatment of choice in the management of polycystic ovarian syndrome (PCOS). the first aim for women with PCOS who are overweight is to make lifestyle changes with a combination of diet and exercise in order to lose weight and improve ovarian function. Please consult your doctor before taking metformin for PCOS.

Q.

Can I take metformin for weight loss?
No, metformin is not indicated for weight loss although it may reduce the weight of obese patients with type 2 diabetes mellitus.

Q.

How long can I take metformin for polycystic ovarian syndrome (PCOS)?
Metformin should be taken at prescribed doses for the prescribed duration only as advised by your doctor. Also refer to the question above.

Q.

Can I take metformin for polycystic ovarian syndrome (PCOS) while pregnant?
No relevant data is available for use of metformin in pregnancy. Animal studies do not indicate any harmful effect. Please consult your doctor before taking metformin during pregnancy. Also refer to the question above.

Q.

How long can I take metformin for?
Metformin should be taken at prescribed doses for the prescribed duration only as advised by your doctor.

Q.

Is metformin an insulin?
No, metformin is not an insulin.

Q.

Is metformin a banned drug?
No, metformin is not a banned drug.

Q.

Is metformin a birth control pill?
No, metformin is not a birth control pill.

Q.

Is metformin a statin?
No, metformin is not a statin.

WHAT OUR USERS ARE SAYING ABOUT ISTAMET 50 MG/500 MG TABLET

How effective is this medicine?

Effective
72%
Moderately effective
13%
Can't say
10%
Not effective
5%

Do you find this medicine expensive?

Yes
88%
No
12%

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Content on this page was last updated on 03 February, 2017, by Dr. Varun Gupta (MD Pharmacology)