Isonex 300 mg Tablet

Prescription Required


Uses of Isonex Tablet

Isonex 300 mg Tablet is used in the treatment of tuberculosis. It is also used to treat inactive (latent) TB .

Isonex Tablet side effects

  • Peripheral neuropathy (tingling and numbness of feet and hand)
  • Increased liver enzymes
  • Hepatitis (viral infection of liver)
  • Jaundice

How to use Isonex Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Isonex 300 mg Tablet is to be taken empty stomach.
Avoid Isonex 300 mg Tablet with tyramine-rich food such as cheese, smoked fish, meats and some types of beer.

How Isonex Tablet works

Isonex 300 mg Tablet is an antibiotic. It works by killing the bacteria that causes tuberculosis.

Isonex Tablet related warnings

Isonex 300 mg Tablet may cause symptoms such as flushing, increased heartbeat, nausea, thirst, chest pain and low blood pressure with alcohol (Disulfiram reactions).
Isonex 300 mg Tablet may be unsafe to use during pregnancy.
Animal studies have shown adverse effects on the foetus, however, there are limited human studies. The benefits from use in pregnant women may be acceptable despite the risk. Please consult your doctor.
Isonex 300 mg Tablet is safe to use during lactation. Human studies have shown that either the drug does not pass into the breastmilk in significant amount or is not expected to cause toxicity to the baby.
Do not drive unless you are feeling well.
Isonex 300 mg Tablet can cause fits, mental health problems and optic neuritis (inflammation of the optic nerve that may cause loss of vision.) This may affect your driving ability.
Isonex 300 mg Tablet is safe to use in patients with kidney disease. No dose adjustment of Isonex 300 mg Tablet is recommended.
However, talk to your doctor if you have any underlying kidney disease.
Isonex 300 mg Tablet should be used with caution in patients with liver disease. Dose adjustment of Isonex 300 mg Tablet may be needed. Please consult your doctor.
Use of Isonex 300 mg Tablet is not recommended in patients with severe liver disease.

What if you miss a dose of Isonex Tablet?

If you miss a dose of Isonex 300 mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

Alternate Brands

For informational purposes only. Consult a doctor before taking any medicines.
Isonex 300 mg Tablet
Solonex Tablet
Macleods Pharmaceuticals Pvt Ltd
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Isoniazid 300mg Tablet
Cadila Pharmaceuticals Ltd
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Isonij 300mg Tablet
Sunij Pharma Pvt Ltd
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Expert Advice

  • Your doctor has prescribed Isonex 300 mg Tablet to cure your infection and improve symptoms.
  • It is best taken on an empty stomach.
  • You must also take a vitamin B6 supplement while on Isonex 300 mg Tablet.
  • Tell your doctor immediately if you experience vision changes, loss of appetite, tiredness, stomach pain, nausea or vomiting, yellow skin or eyes or dark-colored urine.

Interaction with Drugs

Taking Isonex with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Brand(s): Panik
Brand(s): Risure
Brand(s): Ketozoe, Ketazol
Brand(s): Konit
Brand(s): Carz, Antep
Brand(s): Psycopan
Brand(s): Eurolam, Alwel, Tenzo
Brand(s): Etizom
Brand(s): Equblam
Brand(s): Dizapam


Q. Is Isonex an antibiotic?
Isonex is an antibiotic used in the prevention and treatment of tuberculosis or TB (a serious infection caused by bacteria that affects the lungs and in certain cases other parts of the body)
Q. Is Isonex chemotherapy/chemotherapy drug?
Isonex is a primary antibiotic used for treatment of tuberculosis. Do not confuse it with chemotherapy or chemo drugs used for the treatment of cancer
Q. Is Isonex bacteriostatic or bactericidal?
Isonex is a bacteriostatic antibiotic. It stops or suppresses growth of tuberculosis causing bacteria by interfering with the formation of protective outer covering (cell wall) which is essential for their growth
Q. Is Isonex safe?
Yes. Isonex is safe if used at prescribed doses for the prescribed duration as advised by your doctor
Q. Is Isonex a MAOI?
Isonex has very weak inhibitory activity on enzymes monoamine oxidases (MAO); however it is not used as a monoamine oxidase inhibitor (MAOI)
Q. Is Isonex a sulfa drug?
No. The chemical structure and mechanism of action of Isonex is different from sulfa drugs
Q. Is Isonex an inducer or inhibitor?
Isonex is an inhibitor (decreases activity) of an important liver enzyme system that is responsible for the final processing and elimination of several drugs from the body
Q. Can I take isoniazid with ibuprofen/Benadryl/Nyquil/Aleve/Mucinex/amoxicillin?
There no known serious drug interactions of isoniazid with ibuprofen, paracetamol (trade name: Tylenol), naproxen (trade name: Aleve), amoxicillin or any active drug present in Nyquil or Mucinex. Please inform your doctor about all the medication you are currently taking to avoid interactions that may reduce effectiveness of any treatment or aggravate side effects
Q. Does Isonex cause weight loss/weight gain/hair loss/diarrhea/affect menstruation?
Changes in body weight (gain/loss), hair loss, diarrhea or changes in menstruation are not among the known side effects of Isonex. You may experience few of these side effects while on multi drug (including Isonex) treatment for tuberculosis
Q. Does Isonex cause acne/make you tired/cause constipation?
You may experience unusual tiredness, constipation or acne while on treatment with Isonex. Please inform your doctor about all the medication you are currently taking to avoid interactions that may reduce effectiveness of any treatment or aggravate side effects
Q. Does Isonex affect birth control?
Isonex has no known interaction with commonly used oral contraceptives (birth control pills). However, multidrug treatment for tuberculosis contains active drug rifampin that decreases the effectiveness of oral contraceptives and hampers birth control.
Information last updated by Dr. Varun Gupta, MD Pharmacology on 13th Feb 2018.
The medicine details are for information purpose only. Consult a doctor before taking any medicine.
Manufacturer/Marketer Address
The Capital, 1802, 18th Floor , Plot No. C-70, ‘G’ Block , Bandra Kurla Complex, Bandra East , Mumbai – 400051.
We do not facilitate sale of this product at present