Isokin 300 mg/10 mg Tablet

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Pfizer Ltd

Composition for Isokin 300 mg/10 mg Tablet

iconPrescription Required
Potentiallyunsafewith
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Alcohol
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Pregnancy
33.23
₹3.32/Tablet
10 tablets in 1 strip
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Medicine Overview of Isokin 300 mg/10 mg Tablet

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Uses of Isoniazid

Isoniazid is used in the treatment of tuberculosis (TB).
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Side effects of Isoniazid

Common

Peripheral neuropathy (tingling and numbness of feet and hand), Increased liver enzymes, Hepatitis (viral infection of liver), Jaundice.

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How to use Isoniazid

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Avoid Isokin 300 mg/10 mg Tablet with tyramine-rich food such as cheese, smoked fish, meats and some types of beer.

How Isokin 300 mg/10 mg Tablet works

Isoniazid is an antibiotic. It works by killing the bacteria that causes tuberculosis.
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Uses of Vitamin B6 (Pyridoxine)

Vitamin B6 (Pyridoxine) is used in the treatment of Nutritional deficiencies.
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Side effects of Vitamin B6 (Pyridoxine)

Common

Burning sensation, Tightness sensation, Headache, Nausea, Sleepiness, Stomach upset, Pricking sensation, Tingling sensation.

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How to use Vitamin B6 (Pyridoxine)

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Avoid Isokin 300 mg/10 mg Tablet with tyramine-rich food such as cheese, smoked fish, meats and some types of beer.

How Isokin 300 mg/10 mg Tablet works

Vitamin b6 (pyridoxine) provides essential nutrients.

In Depth Information on Isokin 300 mg/10 mg Tablet

Expert advice for Isoniazid

  • Do not take isoniazid, if you have severe liver problems or if you have taken isoniazid in the past and it caused liver problems, fever, chills, joint pain, or severe allergic reaction.
  • Contact your doctor immediately, if you experience symptoms such unusual tiredness (fatigue), weakness, feeling of discomfort (malaise), loss of appetite (anorexia), urge to vomit (nausea) or vomiting while taking isoniazid. It indicates that you are progressing towards liver damage.
  • Do consult your doctor before taking isoniazid if you are aged above 35 years. The frequency of isoniazid related inflammation of liver (hepatitis) is higher in individuals older than 35 years of age. The doctor may advice measurement of blood levels of enzyme transferases before starting treatment with isoniazid.
  • Avoid drinking alcohol. It may increase your risk of liver damage while you are taking isoniazid.
  • Do consult your doctor before taking isoniazid, if you are pregnant or planning to become pregnant or are breastfeeding.
  • Isoniazid interacts with many drugs. Please inform your doctor about all the medication you are currently taking to avoid interactions that may reduce effectiveness of any treatment or aggravate side effects.
  • Do not stop taking isoniazid without consulting your doctor.
  • If you forget to take a dose of Isoniazid, take it as soon as you remember. Do not double the dose to make up for the missed dose.
Warnings
Special precautions for Isokin 300 mg/10 mg Tablet
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Alcohol
CAUTION
Isokin 300 mg/10 mg Tablet may cause symptoms such as flushi
ng, increased heartbeat, nausea, thirst, chest pain and low blood pressure with alcohol (Disulfiram reactions).
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Pregnancy
WEIGH RISKS VS BENEFITS
Isokin 300 mg/10 mg Tablet may be unsafe to use during pregnancy.

Animal studies have shown adverse effects on the foetus, however, there are limited human studies. The benefits from use in pregnant women may be acceptable despite the risk. Please consult your doctor.
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Lactation
SAFE
Isokin 300 mg/10 mg Tablet is safe to use during lactation.
Human studies have shown that either the drug does not pass into the breastmilk in significant amount or is not expected to cause toxicity to the baby.
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Driving
Isokin 300 mg/10 mg Tablet may make you feel dizzy, sleepy, tired, or decrease alertness. If this happens, do not drive.

Caution is advised when driving or operating machinery.
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Kidney
There is limited information available on the use of Isokin
300 mg/10 mg Tablet in patients with kidney disease. Please consult your doctor.
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Liver
There is no data available. Please consult doctor before consuming the drug.

Patient Concerns

Frequently asked questions for Isokin 300 mg/10 mg Tablet

Frequently asked questions for Isoniazid

Q. Is Isoniazid an antibiotic?
Isoniazid is an antibiotic used in the prevention and treatment of tuberculosis or TB (a serious infection caused by bacteria that affects the lungs and in certain cases other parts of the body)
Q. Is Isoniazid chemotherapy/chemotherapy drug?
Isoniazid is a primary antibiotic used for treatment of tuberculosis. Do not confuse it with chemotherapy or chemo drugs used for the treatment of cancer
Q. Is Isoniazid bacteriostatic or bactericidal?
Isoniazid is a bacteriostatic antibiotic. It stops or suppresses growth of tuberculosis causing bacteria by interfering with the formation of protective outer covering (cell wall) which is essential for their growth
Q. Is Isoniazid safe?
Yes. Isoniazid is safe if used at prescribed doses for the prescribed duration as advised by your doctor
Q. Is Isoniazid a MAOI?
Isoniazid has very weak inhibitory activity on enzymes monoamine oxidases (MAO); however it is not used as a monoamine oxidase inhibitor (MAOI)
Q. Is Isoniazid a sulfa drug?
No. The chemical structure and mechanism of action of Isoniazid is different from sulfa drugs
Q. Is Isoniazid an inducer or inhibitor?
Isoniazid is an inhibitor (decreases activity) of an important liver enzyme system that is responsible for the final processing and elimination of several drugs from the body
Q. Can I take isoniazid with ibuprofen/Benadryl/Nyquil/Aleve/Mucinex/amoxicillin?
There no known serious drug interactions of isoniazid with ibuprofen, paracetamol (trade name: Tylenol), naproxen (trade name: Aleve), amoxicillin or any active drug present in Nyquil or Mucinex. Please inform your doctor about all the medication you are currently taking to avoid interactions that may reduce effectiveness of any treatment or aggravate side effects
Q. Does Isoniazid cause weight loss/weight gain/hair loss/diarrhea/affect menstruation?
Changes in body weight (gain/loss), hair loss, diarrhea or changes in menstruation are not among the known side effects of Isoniazid. You may experience few of these side effects while on multi drug (including Isoniazid) treatment for tuberculosis
Q. Does Isoniazid cause acne/make you tired/cause constipation?
You may experience unusual tiredness, constipation or acne while on treatment with Isoniazid. Please inform your doctor about all the medication you are currently taking to avoid interactions that may reduce effectiveness of any treatment or aggravate side effects
Q. Does Isoniazid affect birth control?
Isoniazid has no known interaction with commonly used oral contraceptives (birth control pills). However, multidrug treatment for tuberculosis contains active drug rifampin that decreases the effectiveness of oral contraceptives and hampers birth control.
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